Page last updated: 2024-10-06

Validated targets of C-MYC transcriptional repression

Proteins (62)

ProteinSynonymsTaxonomy
4-trimethylaminobutyraldehyde dehydrogenaseTMABA-DH; TMABALDH; EC 1.2.1.47; Aldehyde dehydrogenase E3 isozyme; Aldehyde dehydrogenase family 9 member A1; 1.2.1.3; Gamma-aminobutyraldehyde dehydrogenase; 1.2.1.19; R-aminobutyraldehyde dehydrogenaseHomo sapiens (human)
Histone deacetylase 3HD3; EC 3.5.1.98; RPD3-2; SMAP45Homo sapiens (human)
Receptor tyrosine-protein kinase erbB-2EC 2.7.10.1; Metastatic lymph node gene 19 protein; MLN 19; Proto-oncogene Neu; Proto-oncogene c-ErbB-2; Tyrosine kinase-type cell surface receptor HER2; p185erbB2Homo sapiens (human)
Integrin beta-1Fibronectin receptor subunit beta; Glycoprotein IIa; GPIIA; VLA-4 subunit betaHomo sapiens (human)
Platelet-derived growth factor receptor betaPDGF-R-beta; PDGFR-beta; EC 2.7.10.1; Beta platelet-derived growth factor receptor; Beta-type platelet-derived growth factor receptor; CD140 antigen-like family member B; Platelet-derived growth factor receptor 1; PDGFR-1Homo sapiens (human)
G1/S-specific cyclin-D1B-cell lymphoma 1 protein; BCL-1; BCL-1 oncogene; PRAD1 oncogeneHomo sapiens (human)
Histone deacetylase 1HD1; EC 3.5.1.98Homo sapiens (human)
Serine/threonine-protein phosphatase 2A activatorEC 5.2.1.8; PP2A, subunit B', PR53 isoform; Phosphotyrosyl phosphatase activator; PTPA; Serine/threonine-protein phosphatase 2A regulatory subunit 4; Serine/threonine-protein phosphatase 2A regulatory subunit B'Homo sapiens (human)
Integrin alpha-6CD49 antigen-like family member F; VLA-6Homo sapiens (human)
Apoptosis regulator Bcl-2Homo sapiens (human)
Histone acetyltransferase p300p300 HAT; EC 2.3.1.48; E1A-associated protein p300; Histone butyryltransferase p300; 2.3.1.-; Histone crotonyltransferase p300; 2.3.1.-; Protein 2-hydroxyisobutyryltransferase p300; 2.3.1.-; Protein propionyltransferase p300; 2.3.1.-Homo sapiens (human)
Zinc finger and BTB domain-containing protein 17Myc-interacting zinc finger protein 1; Miz-1; Zinc finger protein 151; Zinc finger protein 60Homo sapiens (human)
Cyclin-dependent kinase inhibitor 1BCyclin-dependent kinase inhibitor p27; p27Kip1Homo sapiens (human)
Collagen alpha-2(I) chainAlpha-2 type I collagenHomo sapiens (human)
Forkhead box protein O3AF6q21 protein; Forkhead in rhabdomyosarcoma-like 1Homo sapiens (human)
Dickkopf-related protein 1Dickkopf-1; Dkk-1; hDkk-1; SKHomo sapiens (human)
C-C motif chemokine 5EoCP; Eosinophil chemotactic cytokine; SIS-delta; Small-inducible cytokine A5; T cell-specific protein P228; TCP228; T-cell-specific protein RANTESHomo sapiens (human)
Cyclic AMP-responsive element-binding protein 1CREB-1; cAMP-responsive element-binding protein 1Homo sapiens (human)
Protein maxClass D basic helix-loop-helix protein 4; bHLHd4; Myc-associated factor XHomo sapiens (human)
Secreted frizzled-related protein 1FRP-1; sFRP-1; Secreted apoptosis-related protein 2; SARP-2Homo sapiens (human)
Cold shock domain-containing protein E1N-ras upstream gene protein; Protein UNRHomo sapiens (human)
CASP8 and FADD-like apoptosis regulatorCaspase homolog; CASH; Caspase-eight-related protein; Casper; Caspase-like apoptosis regulatory protein; CLARP; Cellular FLICE-like inhibitory protein; c-FLIP; FADD-like antiapoptotic molecule 1; FLAME-1; Inhibitor of FLICE; I-FLICE; MACH-related inducer Homo sapiens (human)
Myc proto-oncogene proteinClass E basic helix-loop-helix protein 39; bHLHe39; Proto-oncogene c-Myc; Transcription factor p64Homo sapiens (human)
DNA nucleotidylexotransferaseEC 2.7.7.31; Terminal addition enzyme; Terminal deoxynucleotidyltransferase; Terminal transferaseHomo sapiens (human)
Galectin-1Gal-1; 14 kDa laminin-binding protein; HLBP14; 14 kDa lectin; Beta-galactoside-binding lectin L-14-I; Galaptin; HBL; HPL; Lactose-binding lectin 1; Lectin galactoside-binding soluble 1; Putative MAPK-activating protein PM12; S-Lac lectin 1Homo sapiens (human)
Breast cancer type 1 susceptibility proteinEC 2.3.2.27; RING finger protein 53; RING-type E3 ubiquitin transferase BRCA1Homo sapiens (human)
Cyclin-dependent kinase inhibitor 1CDK-interacting protein 1; Melanoma differentiation-associated protein 6; MDA-6; p21Homo sapiens (human)
Natural resistance-associated macrophage protein 1NRAMP 1; Solute carrier family 11 member 1Homo sapiens (human)
Mothers against decapentaplegic homolog 2MAD homolog 2; Mothers against DPP homolog 2; JV18-1; Mad-related protein 2; hMAD-2; SMAD family member 2; SMAD 2; Smad2; hSMAD2Homo sapiens (human)
DNA (cytosine-5)-methyltransferase 3ADnmt3a; EC 2.1.1.37; DNA methyltransferase HsaIIIA; DNA MTase HsaIIIA; M.HsaIIIAHomo sapiens (human)
Transcription factor Sp1Homo sapiens (human)
DNA damage-inducible transcript 3 proteinDDIT-3; C/EBP zeta; C/EBP-homologous protein; CHOP; C/EBP-homologous protein 10; CHOP-10; CCAAT/enhancer-binding protein homologous protein; Growth arrest and DNA damage-inducible protein GADD153Homo sapiens (human)
Retinoblastoma-like protein 1107 kDa retinoblastoma-associated protein; p107; pRb1Homo sapiens (human)
Hydroxymethylglutaryl-CoA synthase, mitochondrialHMG-CoA synthase; EC 2.3.3.10; 3-hydroxy-3-methylglutaryl coenzyme A synthaseHomo sapiens (human)
Mothers against decapentaplegic homolog 4MAD homolog 4; Mothers against DPP homolog 4; Deletion target in pancreatic carcinoma 4; SMAD family member 4; SMAD 4; Smad4; hSMAD4Homo sapiens (human)
Ferritin heavy chainFerritin H subunit; EC 1.16.3.1; Cell proliferation-inducing gene 15 proteinHomo sapiens (human)
Cyclin-dependent kinase 4 inhibitor BMultiple tumor suppressor 2; MTS-2; p14-INK4b; p15-INK4b; p15INK4BHomo sapiens (human)
Protein NDRG1Differentiation-related gene 1 protein; DRG-1; N-myc downstream-regulated gene 1 protein; Nickel-specific induction protein Cap43; Reducing agents and tunicamycin-responsive protein; RTP; Rit42Homo sapiens (human)
ClusterinAging-associated gene 4 protein; Apolipoprotein J; Apo-J; Complement cytolysis inhibitor; CLI; Complement-associated protein SP-40,40; Ku70-binding protein 1; NA1/NA2; Sulfated glycoprotein 2; SGP-2; Testosterone-repressed prostate message 2; TRPM-2Homo sapiens (human)
mRNA decay activator protein ZFP36L1Butyrate response factor 1; EGF-response factor 1; ERF-1; TPA-induced sequence 11b; Zinc finger protein 36, C3H1 type-like 1; ZFP36-like 1Homo sapiens (human)
Protein Wnt-5aHomo sapiens (human)
Tight junction protein ZO-2Tight junction protein 2; Zona occludens protein 2; Zonula occludens protein 2Homo sapiens (human)
CCAAT/enhancer-binding protein alphaC/EBP alphaHomo sapiens (human)
CCAAT/enhancer-binding protein deltaC/EBP delta; Nuclear factor NF-IL6-beta; NF-IL6-betaHomo sapiens (human)
Protein NDRG2N-myc downstream-regulated gene 2 protein; Protein Syld709613Homo sapiens (human)
Integrin beta-4GP150Homo sapiens (human)
Transcription factor PU.131 kDa-transforming proteinHomo sapiens (human)
TATA-box-binding proteinTATA sequence-binding protein; TATA-binding factor; TATA-box factor; Transcription initiation factor TFIID TBP subunitHomo sapiens (human)
Nuclear transcription factor Y subunit alphaCAAT box DNA-binding protein subunit A; Nuclear transcription factor Y subunit A; NF-YAHomo sapiens (human)
Growth arrest and DNA damage-inducible protein GADD45 alphaDNA damage-inducible transcript 1 protein; DDIT-1Homo sapiens (human)
Nuclear transcription factor Y subunit betaCAAT box DNA-binding protein subunit B; Nuclear transcription factor Y subunit B; NF-YBHomo sapiens (human)
Protein S100-A7Psoriasin; S100 calcium-binding protein A7Homo sapiens (human)
TuberinTuberous sclerosis 2 proteinHomo sapiens (human)
DNA-binding protein inhibitor ID-2Class B basic helix-loop-helix protein 26; bHLHb26; Inhibitor of DNA binding 2; Inhibitor of differentiation 2Homo sapiens (human)
Interferon regulatory factor 8IRF-8; Interferon consensus sequence-binding protein; H-ICSBP; ICSBPHomo sapiens (human)
General transcription factor IIH subunit 2Basic transcription factor 2 44 kDa subunit; BTF2 p44; General transcription factor IIH polypeptide 2; TFIIH basal transcription factor complex p44 subunitHomo sapiens (human)
Nuclear transcription factor Y subunit gammaCAAT box DNA-binding protein subunit C; Nuclear transcription factor Y subunit C; NF-YC; Transactivator HSM-1/2Homo sapiens (human)
Max dimerization protein 4Max dimerizer 4; Class C basic helix-loop-helix protein 12; bHLHc12; Max-associated protein 4; Max-interacting transcriptional repressor MAD4Homo sapiens (human)
Zinc finger protein Gfi-1Growth factor independent protein 1; Zinc finger protein 163Homo sapiens (human)
Sideroflexin-3Homo sapiens (human)
Transmembrane protein 126AHomo sapiens (human)
Tomoregulin-2TR-2; Hyperplastic polyposis protein 1; Transmembrane protein with EGF-like and two follistatin-like domainsHomo sapiens (human)

Compounds (0)

CompoundDescription