Page last updated: 2024-10-06

Validated targets of C-MYC transcriptional activation

Proteins (78)

ProteinSynonymsTaxonomy
NibrinCell cycle regulatory protein p95; Nijmegen breakage syndrome protein 1Homo sapiens (human)
Thioredoxin-dependent peroxide reductase, mitochondrialEC 1.11.1.24; Antioxidant protein 1; AOP-1; HBC189; Peroxiredoxin III; Prx-III; Peroxiredoxin-3; Protein MER5 homolog; Thioredoxin-dependent peroxiredoxin 3Homo sapiens (human)
Heat shock 70 kDa protein 4HSP70RY; Heat shock 70-related protein APG-2Homo sapiens (human)
Polycomb complex protein BMI-1Polycomb group RING finger protein 4; RING finger protein 51Homo sapiens (human)
Phorbol-12-myristate-13-acetate-induced protein 1PMA-induced protein 1; Immediate-early-response protein APR; Protein NoxaHomo sapiens (human)
Ribosomal oxygenase 260S ribosomal protein L27a histidine hydroxylase; Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA; 1.14.11.-; Histone lysine demethylase MINA; MYC-induced nuclear antigen; Mineral dust-induced gene protein; Nucleolar protein 52; RibHomo sapiens (human)
Glyceraldehyde-3-phosphate dehydrogenaseGAPDH; EC 1.2.1.12; Peptidyl-cysteine S-nitrosylase GAPDH; 2.6.99.-Homo sapiens (human)
Cellular tumor antigen p53Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53Homo sapiens (human)
Eukaryotic translation initiation factor 4EeIF-4E; eIF4E; eIF-4F 25 kDa subunit; mRNA cap-binding proteinHomo sapiens (human)
Heat shock protein HSP 90-alphaEC 3.6.4.10; Heat shock 86 kDa; HSP 86; HSP86; Lipopolysaccharide-associated protein 2; LAP-2; LPS-associated protein 2; Renal carcinoma antigen NY-REN-38Homo sapiens (human)
Serine/threonine-protein kinase pim-1EC 2.7.11.1Homo sapiens (human)
G2/mitotic-specific cyclin-B1Homo sapiens (human)
60 kDa heat shock protein, mitochondrialEC 5.6.1.7; 60 kDa chaperonin; Chaperonin 60; CPN60; Heat shock protein 60; HSP-60; Hsp60; HuCHA60; Mitochondrial matrix protein P1; P60 lymphocyte proteinHomo sapiens (human)
Eukaryotic translation initiation factor 4 gamma 1eIF-4-gamma 1; eIF-4G 1; eIF-4G1; p220Homo sapiens (human)
Serine hydroxymethyltransferase, cytosolicSHMT; EC 2.1.2.1; Glycine hydroxymethyltransferase; Serine methylaseHomo sapiens (human)
Telomerase reverse transcriptaseEC 2.7.7.49; HEST2; Telomerase catalytic subunit; Telomerase-associated protein 2; TP2Homo sapiens (human)
L-lactate dehydrogenase A chainLDH-A; EC 1.1.1.27; Cell proliferation-inducing gene 19 protein; LDH muscle subunit; LDH-M; Renal carcinoma antigen NY-REN-59Homo sapiens (human)
Solute carrier family 2, facilitated glucose transporter member 1Glucose transporter type 1, erythrocyte/brain; GLUT-1; HepG2 glucose transporterHomo sapiens (human)
Cyclin-dependent kinase 4EC 2.7.11.22; Cell division protein kinase 4; PSK-J3Homo sapiens (human)
Matrix metalloproteinase-9MMP-9; EC 3.4.24.35; 92 kDa gelatinase; 92 kDa type IV collagenase; Gelatinase B; GELBHomo sapiens (human)
Apoptosis regulator BAX Bcl-2-like protein 4; Bcl2-L-4Homo sapiens (human)
E3 ubiquitin-protein ligase HUWE1EC 2.3.2.26; ARF-binding protein 1; ARF-BP1; HECT, UBA and WWE domain-containing protein 1; HECT-type E3 ubiquitin transferase HUWE1; Homologous to E6AP carboxyl terminus homologous protein 9; HectH9; Large structure of UREB1; LASU1; Mcl-1 ubiquitin ligasHomo sapiens (human)
Eukaryotic translation initiation factor 2 subunit 1Eukaryotic translation initiation factor 2 subunit alpha; eIF-2-alpha; eIF-2A; eIF-2alphaHomo sapiens (human)
ATP-dependent 6-phosphofructokinase, muscle typeATP-PFK; PFK-M; EC 2.7.1.11; 6-phosphofructokinase type A; Phosphofructo-1-kinase isozyme A; PFK-A; PhosphohexokinaseHomo sapiens (human)
Ornithine decarboxylaseODC; EC 4.1.1.17Homo sapiens (human)
Nucleoside diphosphate kinase ANDK A; NDP kinase A; EC 2.7.4.6; Granzyme A-activated DNase; GAAD; Metastasis inhibition factor nm23; NM23-H1; Tumor metastatic process-associated proteinHomo sapiens (human)
Nucleoside diphosphate kinase BNDK B; NDP kinase B; EC 2.7.4.6; C-myc purine-binding transcription factor PUF; Histidine protein kinase NDKB; 2.7.13.3; nm23-H2Homo sapiens (human)
Protein maxClass D basic helix-loop-helix protein 4; bHLHd4; Myc-associated factor XHomo sapiens (human)
Histone acetyltransferase KAT2AEC 2.3.1.48; General control of amino acid synthesis protein 5-like 2; Histone acetyltransferase GCN5; hGCN5; Histone glutaryltransferase KAT2A; 2.3.1.-; Histone succinyltransferase KAT2A; 2.3.1.-; Lysine acetyltransferase 2A; STAF97Homo sapiens (human)
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2B17.2-like; B17.2L; Mimitin; Myc-induced mitochondrial protein; MMTN; NDUFA12-like proteinHomo sapiens (human)
ATP-dependent RNA helicase DDX18EC 3.6.4.13; DEAD box protein 18; Myc-regulated DEAD box protein; MrDbHomo sapiens (human)
Branched-chain-amino-acid aminotransferase, cytosolicBCAT(c); EC 2.6.1.42; Protein ECA39Homo sapiens (human)
RuvB-like 2EC 3.6.4.12; 48 kDa TATA box-binding protein-interacting protein; 48 kDa TBP-interacting protein; 51 kDa erythrocyte cytosolic protein; ECP-51; INO80 complex subunit J; Repressing pontin 52; Reptin 52; TIP49b; TIP60-associated protein 54-beta; TAP54-betaHomo sapiens (human)
Alpha-enolaseEC 4.2.1.11; 2-phospho-D-glycerate hydro-lyase; C-myc promoter-binding protein; Enolase 1; MBP-1; MPB-1; Non-neural enolase; NNE; Phosphopyruvate hydratase; Plasminogen-binding proteinHomo sapiens (human)
Baculoviral IAP repeat-containing protein 5Apoptosis inhibitor 4; Apoptosis inhibitor survivinHomo sapiens (human)
Myc proto-oncogene proteinClass E basic helix-loop-helix protein 39; bHLHe39; Proto-oncogene c-Myc; Transcription factor p64Homo sapiens (human)
Thymidine kinase, cytosolicEC 2.7.1.21Homo sapiens (human)
NucleophosminNPM; Nucleolar phosphoprotein B23; Nucleolar protein NO38; NumatrinHomo sapiens (human)
M-phase inducer phosphatase 1EC 3.1.3.48; Dual specificity phosphatase Cdc25AHomo sapiens (human)
Eukaryotic initiation factor 4A-IeIF-4A-I; eIF4A-I; EC 3.6.4.13; ATP-dependent RNA helicase eIF4A-1Homo sapiens (human)
60S ribosomal protein L11CLL-associated antigen KW-12; Large ribosomal subunit protein uL5Homo sapiens (human)
Mothers against decapentaplegic homolog 3MAD homolog 3; Mad3; Mothers against DPP homolog 3; hMAD-3; JV15-2; SMAD family member 3; SMAD 3; Smad3; hSMAD3Homo sapiens (human)
Histone acetyltransferase KAT5EC 2.3.1.48; 60 kDa Tat-interactive protein; Tip60; Histone acetyltransferase HTATIP; HIV-1 Tat interactive protein; Lysine acetyltransferase 5; cPLA(2)-interacting proteinHomo sapiens (human)
RuvB-like 1EC 3.6.4.12; 49 kDa TATA box-binding protein-interacting protein; 49 kDa TBP-interacting protein; 54 kDa erythrocyte cytosolic protein; ECP-54; INO80 complex subunit H; Nuclear matrix protein 238; NMP 238; Pontin 52; TIP49a; TIP60-associated protein 54-alHomo sapiens (human)
CAD proteinHomo sapiens (human)
NucleolinProtein C23Homo sapiens (human)
Transferrin receptor protein 1TR; TfR; TfR1; Trfr; T9; p90Homo sapiens (human)
Fos-related antigen 1FRA-1Homo sapiens (human)
Mothers against decapentaplegic homolog 4MAD homolog 4; Mothers against DPP homolog 4; Deletion target in pancreatic carcinoma 4; SMAD family member 4; SMAD 4; Smad4; hSMAD4Homo sapiens (human)
Iron-responsive element-binding protein 2IRE-BP 2; Iron regulatory protein 2; IRP2Homo sapiens (human)
G1/S-specific cyclin-D2Homo sapiens (human)
Protein lin-28 homolog BLin-28BHomo sapiens (human)
Glycerol-3-phosphate acyltransferase 1, mitochondrialGPAT-1; EC 2.3.1.15Homo sapiens (human)
Prothymosin alphaHomo sapiens (human)
NeuroserpinPeptidase inhibitor 12; PI-12; Serpin I1Homo sapiens (human)
Protein LYRIC3D3/LYRIC; Astrocyte elevated gene-1 protein; AEG-1; Lysine-rich CEACAM1 co-isolated protein; Metadherin; Metastasis adhesion proteinHomo sapiens (human)
Cell division cycle-associated protein 7Protein JPO1Homo sapiens (human)
Myc target protein 1Myc target in myeloid cells protein 1Homo sapiens (human)
Transcription factor E2F3E2F-3Homo sapiens (human)
H/ACA ribonucleoprotein complex subunit DKC1EC 5.4.99.-; CBF5 homolog; Dyskerin; Nopp140-associated protein of 57 kDa; Nucleolar protein NAP57; Nucleolar protein family A member 4; snoRNP protein DKC1Homo sapiens (human)
Transcription initiation protein SPT3 homologSPT3-like proteinHomo sapiens (human)
STAGA complex 65 subunit gammaAdenocarcinoma antigen ART1; SPTF-associated factor 65 gamma; STAF65gamma; Suppressor of Ty 7-likeHomo sapiens (human)
Zinc finger protein SNAI1Protein snail homolog 1; Protein snaHomo sapiens (human)
Actin-like protein 6A53 kDa BRG1-associated factor A; Actin-related protein Baf53a; ArpNbeta; BRG1-associated factor 53A; BAF53A; INO80 complex subunit KHomo sapiens (human)
DNA-directed RNA polymerase III subunit RPC4RNA polymerase III subunit C4; DNA-directed RNA polymerase III subunit D; Protein BN51; RNA polymerase III 47 kDa subunit; RPC53 homologHomo sapiens (human)
High mobility group protein HMG-I/HMG-YHMG-I(Y); High mobility group AT-hook protein 1; High mobility group protein A1; High mobility group protein RHomo sapiens (human)
Nucleolar transcription factor 1Autoantigen NOR-90; Upstream-binding factor 1; UBF-1Homo sapiens (human)
Regulator of chromosome condensationCell cycle regulatory protein; Chromosome condensation protein 1Homo sapiens (human)
Killer cell immunoglobulin-like receptor 3DL1CD158 antigen-like family member E; HLA-BW4-specific inhibitory NK cell receptor; MHC class I NK cell receptor; Natural killer-associated transcript 3; NKAT-3; p70 natural killer cell receptor clones CL-2/CL-11; p70 NK receptor CL-2/CL-11Homo sapiens (human)
DNA-binding protein inhibitor ID-2Class B basic helix-loop-helix protein 26; bHLHb26; Inhibitor of DNA binding 2; Inhibitor of differentiation 2Homo sapiens (human)
Transcription initiation factor TFIID subunit 10STAF28; Transcription initiation factor TFIID 30 kDa subunit; TAF(II)30; TAFII-30; TAFII30Homo sapiens (human)
Metastasis-associated protein MTA1Homo sapiens (human)
Transcription initiation factor TFIID subunit 12Transcription initiation factor TFIID 20/15 kDa subunits; TAFII-20/TAFII-15; TAFII20/TAFII15Homo sapiens (human)
Transcription initiation factor TFIID subunit 9RNA polymerase II TBP-associated factor subunit G; STAF31/32; Transcription initiation factor TFIID 31 kDa subunit; TAFII-31; TAFII31; Transcription initiation factor TFIID 32 kDa subunit; TAFII-32; TAFII32Homo sapiens (human)
Retrotransposon-derived protein PEG10Embryonal carcinoma differentiation-regulated protein; Mammalian retrotransposon-derived protein 2; Myelin expression factor 3-like protein 1; MEF3-like protein 1; Paternally expressed gene 10 protein; Retrotransposon gag domain-containing protein 3; RetrHomo sapiens (human)
Transcription initiation factor TFIID subunit 4BTranscription initiation factor TFIID 105 kDa subunit; TAF(II)105; TAFII-105; TAFII105Homo sapiens (human)
Programmed cell death protein 10Cerebral cavernous malformations 3 protein; TF-1 cell apoptosis-related protein 15Homo sapiens (human)
Transformation/transcription domain-associated protein350/400 kDa PCAF-associated factor; PAF350/400; STAF40; Tra1 homologHomo sapiens (human)

Compounds (0)

CompoundDescription