VEGF signaling pathway ( VEGF signaling pathway )

Proteins (17)

Protein	Synonyms	Taxonomy
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	PI3-kinase subunit beta; PI3K-beta; PI3Kbeta; PtdIns-3-kinase subunit beta; EC 2.7.1.153; Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta; PtdIns-3-kinase subunit p110-beta; p110beta	Rattus norvegicus (Norway rat)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2	EC 3.1.4.11; Phosphoinositide phospholipase C-gamma-2; Phospholipase C-IV; PLC-IV; Phospholipase C-gamma-2; PLC-gamma-2	Rattus norvegicus (Norway rat)
MAP kinase-activated protein kinase 2	MAPK-activated protein kinase 2; MAPKAP kinase 2; MAPKAP-K2; MAPKAPK-2; MK-2; MK2; EC 2.7.11.1	Mus musculus (house mouse)
Serine/threonine-protein kinase PAK 6	EC 2.7.11.1; PAK-5; p21-activated kinase 6; PAK-6	Homo sapiens (human)
Inositol 1,4,5-trisphosphate receptor type 3	IP3 receptor isoform 3; IP3R 3; InsP3R3; Type 3 inositol 1,4,5-trisphosphate receptor; Type 3 InsP3 receptor	Rattus norvegicus (Norway rat)
Protein kinase C delta type	EC 2.7.11.13; nPKC-delta	Rattus norvegicus (Norway rat)
Vascular endothelial growth factor receptor 2	VEGFR-2; EC 2.7.10.1; Fetal liver kinase 1; FLK-1; Protein-tyrosine kinase receptor flk-1	Rattus norvegicus (Norway rat)
Vascular endothelial growth factor D	VEGF-D; c-Fos-induced growth factor; FIGF	Rattus norvegicus (Norway rat)
RAF proto-oncogene serine/threonine-protein kinase	EC 2.7.11.1; Proto-oncogene c-RAF; cRaf; Raf-1	Mus musculus (house mouse)
SH2 domain-containing protein 2A	Lck-associated adapter protein; Lad; Rlk/Itk-binding protein; Ribp	Mus musculus (house mouse)
Mitogen-activated protein kinase 12	MAP kinase 12; MAPK 12; EC 2.7.11.24; Extracellular signal-regulated kinase 6; ERK-6; Mitogen-activated protein kinase p38 gamma; MAP kinase p38 gamma; Stress-activated protein kinase 3	Rattus norvegicus (Norway rat)
Bcl2-associated agonist of cell death	BAD; Bcl-2-binding component 6; Bcl-xL/Bcl-2-associated death promoter; Bcl2 antagonist of cell death	Rattus norvegicus (Norway rat)
Mitogen-activated protein kinase ERK-A	EC 2.7.11.24; Extracellular-regulated kinase A; Protein rolled	Drosophila melanogaster (fruit fly)
ETS domain-containing protein Elk-1		Mus musculus (house mouse)
Dual specificity mitogen-activated protein kinase kinase mek-2	MAP kinase kinase mek-2; EC 2.7.12.2	Caenorhabditis elegans
Phosphatidylinositol 3-kinase regulatory subunit alpha	PI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; PI3-kinase subunit p85-alpha; PtdIns-3-kinase regulatory subunit p85-alpha	Rattus norvegicus (Norway rat)
Serine/threonine-protein kinase akt-2	EC 2.7.11.1; Protein kinase B akt-2; PKB akt-2	Caenorhabditis elegans

Compounds (2)

Compound	Description
Calcium	A basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
inositol 1,4,5-trisphosphate	Intracellular messenger formed by the action of phospholipase C on phosphatidylinositol 4,5-bisphosphate, which is one of the phospholipids that make up the cell membrane. Inositol 1,4,5-trisphosphate is released into the cytoplasm where it releases calcium ions from internal stores within the cell's endoplasmic reticulum. These calcium ions stimulate the activity of B kinase or calmodulin.

Compound

Description

Calcium

A basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.

inositol 1,4,5-trisphosphate

Intracellular messenger formed by the action of phospholipase C on phosphatidylinositol 4,5-bisphosphate, which is one of the phospholipids that make up the cell membrane. Inositol 1,4,5-trisphosphate is released into the cytoplasm where it releases calcium ions from internal stores within the cell's endoplasmic reticulum. These calcium ions stimulate the activity of B kinase or calmodulin.