Page last updated: 2024-10-06

Ubiquinol biosynthesis

Proteins (8)

ProteinSynonymsTaxonomy
5-demethoxyubiquinone hydroxylase, mitochondrialDMQ hydroxylase; EC 1.14.99.60; Timing protein clk-1 homolog; Ubiquinone biosynthesis monooxygenase COQ7Homo sapiens (human)
Ubiquinone biosynthesis protein COQ9, mitochondrialHomo sapiens (human)
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrialEC 2.1.1.201; Ubiquinone biosynthesis methyltransferase COQ5Homo sapiens (human)
All trans-polyprenyl-diphosphate synthase PDSS1All-trans-decaprenyl-diphosphate synthase subunit 1; 2.5.1.91; Decaprenyl pyrophosphate synthase subunit 1; Decaprenyl-diphosphate synthase subunit 1; Solanesyl-diphosphate synthase subunit 1; Trans-prenyltransferase 1; TPT 1Homo sapiens (human)
All trans-polyprenyl-diphosphate synthase PDSS2All-trans-decaprenyl-diphosphate synthase subunit 2; 2.5.1.91; Candidate tumor suppressor protein; Decaprenyl pyrophosphate synthase subunit 2; Decaprenyl-diphosphate synthase subunit 2; Solanesyl-diphosphate synthase subunit 2Homo sapiens (human)
4-hydroxybenzoate polyprenyltransferase, mitochondrial 4-HB polyprenyltransferase; EC 2.5.1.39; 4-hydroxybenzoate decaprenyltransferase; COQ2 homolog; hCOQ2; Para-hydroxybenzoate--polyprenyltransferase; PHB:PPT; PHB:polyprenyltransferaseHomo sapiens (human)
Ubiquinone biosynthesis O-methyltransferase, mitochondrial3-demethylubiquinol 3-O-methyltransferase; 2.1.1.64; Polyprenyldihydroxybenzoate methyltransferase; 2.1.1.114Homo sapiens (human)
Ubiquinone biosynthesis monooxygenase COQ6, mitochondrialEC 1.14.13.-; Coenzyme Q10 monooxygenase 6Homo sapiens (human)

Compounds (14)

CompoundDescription
hydronium ion
ironA metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN.
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
MagnesiumA metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
OxygenAn element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
ubiquinolreduced forms of ubiquinone; see also record for ubiquinol 10
isopentenyl pyrophosphatesubstrate for isopentenyl pyrophosphate isomerase; RN given refers to unlabeled cpd; a nonpeptide mycobacterial antigen that stimulates gamma delta T cells
4-hydroxybenzoic acid
farnesyl pyrophosphatea sesquiterpene that dimerizes to SQUALENE; RN given refers to cpd without isomeric designation
3-decaprenyl-4-hydroxybenzoateintermediate in biosynthesis of ubiquinone
s-adenosylhomocysteine5'-S-(3-Amino-3-carboxypropyl)-5'-thioadenosine. Formed from S-adenosylmethionine after transmethylation reactions.
Flavin-Adenine DinucleotideA condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase. (Lehninger, Principles of Biochemistry, 1982, p972)
creolinfrom refined coal tar oils