Page last updated: 2024-10-06
Ubiquinol biosynthesis
Proteins (8)
| Protein | Synonyms | Taxonomy |
|---|
| 5-demethoxyubiquinone hydroxylase, mitochondrial | DMQ hydroxylase; EC 1.14.99.60; Timing protein clk-1 homolog; Ubiquinone biosynthesis monooxygenase COQ7 | Homo sapiens (human) |
| Ubiquinone biosynthesis protein COQ9, mitochondrial | | Homo sapiens (human) |
| 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial | EC 2.1.1.201; Ubiquinone biosynthesis methyltransferase COQ5 | Homo sapiens (human) |
| All trans-polyprenyl-diphosphate synthase PDSS1 | All-trans-decaprenyl-diphosphate synthase subunit 1; 2.5.1.91; Decaprenyl pyrophosphate synthase subunit 1; Decaprenyl-diphosphate synthase subunit 1; Solanesyl-diphosphate synthase subunit 1; Trans-prenyltransferase 1; TPT 1 | Homo sapiens (human) |
| All trans-polyprenyl-diphosphate synthase PDSS2 | All-trans-decaprenyl-diphosphate synthase subunit 2; 2.5.1.91; Candidate tumor suppressor protein; Decaprenyl pyrophosphate synthase subunit 2; Decaprenyl-diphosphate synthase subunit 2; Solanesyl-diphosphate synthase subunit 2 | Homo sapiens (human) |
| 4-hydroxybenzoate polyprenyltransferase, mitochondrial | 4-HB polyprenyltransferase; EC 2.5.1.39; 4-hydroxybenzoate decaprenyltransferase; COQ2 homolog; hCOQ2; Para-hydroxybenzoate--polyprenyltransferase; PHB:PPT; PHB:polyprenyltransferase | Homo sapiens (human) |
| Ubiquinone biosynthesis O-methyltransferase, mitochondrial | 3-demethylubiquinol 3-O-methyltransferase; 2.1.1.64; Polyprenyldihydroxybenzoate methyltransferase; 2.1.1.114 | Homo sapiens (human) |
| Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial | EC 1.14.13.-; Coenzyme Q10 monooxygenase 6 | Homo sapiens (human) |
Compounds (14)
| Compound | Description |
|---|
| hydronium ion | |
| iron | A metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN. |
| Carbon Dioxide | A colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals. |
| Magnesium | A metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION. |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| Oxygen | An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration. |
| ubiquinol | reduced forms of ubiquinone; see also record for ubiquinol 10 |
| isopentenyl pyrophosphate | substrate for isopentenyl pyrophosphate isomerase; RN given refers to unlabeled cpd; a nonpeptide mycobacterial antigen that stimulates gamma delta T cells |
| 4-hydroxybenzoic acid | |
| farnesyl pyrophosphate | a sesquiterpene that dimerizes to SQUALENE; RN given refers to cpd without isomeric designation |
| 3-decaprenyl-4-hydroxybenzoate | intermediate in biosynthesis of ubiquinone |
| s-adenosylhomocysteine | 5'-S-(3-Amino-3-carboxypropyl)-5'-thioadenosine. Formed from S-adenosylmethionine after transmethylation reactions. |
| Flavin-Adenine Dinucleotide | A condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase. (Lehninger, Principles of Biochemistry, 1982, p972) |
| creolin | from refined coal tar oils |