Page last updated: 2024-10-06

UMP biosynthesis I

Proteins (12)

ProteinSynonymsTaxonomy
DihydroorotaseDHOase; EC 3.5.2.3Escherichia coli K-12
Uridine 5'-monophosphate synthaseUMP synthaseArabidopsis thaliana (thale cress)
Carbamoyl-phosphate synthase small chainEC 6.3.5.5; Carbamoyl-phosphate synthetase glutamine chainEscherichia coli K-12
CAD proteinHomo sapiens (human)
Orotidine 5'-phosphate decarboxylaseEC 4.1.1.23; OMP decarboxylase; OMPDCase; OMPdecaseEscherichia coli K-12
Dihydroorotate dehydrogenase (quinone)EC 1.3.5.2; DHOdehase; DHOD; DHODase; Dihydroorotate oxidaseEscherichia coli K-12
Dihydroorotate dehydrogenase (quinone), mitochondrialDHOdehase; EC 1.3.5.2; Dihydroorotate oxidaseArabidopsis thaliana (thale cress)
Carbamoyl-phosphate synthase large chainEC 6.3.5.5; Carbamoyl-phosphate synthetase ammonia chainEscherichia coli K-12
Aspartate carbamoyltransferase catalytic subunitEC 2.1.3.2; Aspartate transcarbamylase; ATCaseEscherichia coli K-12
Orotate phosphoribosyltransferaseOPRT; OPRTase; EC 2.4.2.10Escherichia coli K-12
Aspartate carbamoyltransferase regulatory chainEscherichia coli K-12
Aspartate carbamoyltransferase, chloroplasticEC 2.1.3.2; Aspartate transcarbamylase; ATCaseArabidopsis thaliana (thale cress)

Compounds (23)

CompoundDescription
diphosphoric acid
hydronium ion
Succinate
Ammonium
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
ZincA metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn.
Orthophosphate
Flavin MononucleotideA coenzyme for a number of oxidative enzymes including NADH DEHYDROGENASE. It is the principal form in which RIBOFLAVIN is found in cells and tissues.
Aspartate
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
hydrogen carbonate
potassiumAn element in the alkali group of metals with an atomic symbol K, atomic number 19, and atomic weight 39.10. It is the chief cation in the intracellular fluid of muscle and other cells. Potassium ion is a strong electrolyte that plays a significant role in the regulation of fluid volume and maintenance of the WATER-ELECTROLYTE BALANCE.
MagnesiumA metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
cyanatesOrganic salts of cyanic acid containing the -OCN radical.
Carbamyl PhosphateThe monoanhydride of carbamic acid with PHOSPHORIC ACID. It is an important intermediate metabolite and is synthesized enzymatically by CARBAMYL-PHOSPHATE SYNTHASE (AMMONIA) and CARBAMOYL-PHOSPHATE SYNTHASE (GLUTAMINE-HYDROLYZING).
glutamate
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
polyglutamineRN given for (D)-isomer
Cytidine TriphosphateCytidine 5'-(tetrahydrogen triphosphate). A cytosine nucleotide containing three phosphate groups esterified to the sugar moiety.
Uridine Monophosphate5'-Uridylic acid. A uracil nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' position.
orotidylic acidstructure
2-amino-4-oxo-5-chloropentanoateinhibitor of asparagine synthetase; structure