Page last updated: 2024-10-06

UDP-N-acetylmuramoyl-pentapeptide biosynthesis II (lysine-containing)

Proteins (9)

ProteinSynonymsTaxonomy
UDP-N-acetylmuramate--L-alanine ligaseEC 6.3.2.8; UDP-N-acetylmuramoyl-L-alanine synthetaseStaphylococcus aureus
UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1EC 2.5.1.7; Enoylpyruvate transferase 1; UDP-N-acetylglucosamine enolpyruvyl transferase 1; EPT 1Staphylococcus aureus subsp. aureus N315
Glutamate racemaseEC 5.1.1.3Staphylococcus haemolyticus
UDP-N-acetylmuramoylalanine--D-glutamate ligaseEC 6.3.2.9; D-glutamic acid-adding enzyme; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetaseStaphylococcus aureus
UDP-N-acetylenolpyruvoylglucosamine reductaseEC 1.3.1.98; UDP-N-acetylmuramate dehydrogenaseStaphylococcus aureus
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase Staphylococcus aureus subsp. aureus NCTC 8325
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligaseEC 6.3.2.7; L-lysine-adding enzyme; UDP-MurNAc-L-Ala-D-Glu:L-Lys ligase; UDP-MurNAc-tripeptide synthetase; UDP-N-acetylmuramyl-tripeptide synthetaseStaphylococcus aureus subsp. aureus COL
UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2EC 2.5.1.7; Enoylpyruvate transferase 2; UDP-N-acetylglucosamine enolpyruvyl transferase 2; EPT 2Staphylococcus aureus subsp. aureus N315
D-alanine--D-alanine ligaseEC 6.3.2.4; D-Ala-D-Ala ligase; D-alanylalanine synthetaseStaphylococcus aureus subsp. aureus COL

Compounds (14)

CompoundDescription
hydronium ion
CobaltA trace element that is a component of vitamin B12. It has the atomic symbol Co, atomic number 27, and atomic weight 58.93. It is used in nuclear weapons, alloys, and pigments. Deficiency in animals leads to anemia; its excess in humans can lead to erythrocytosis.
ManganeseA trace element with atomic symbol Mn, atomic number 25, and atomic weight 54.94. It is concentrated in cell mitochondria, mostly in the pituitary gland, liver, pancreas, kidney, and bone, influences the synthesis of mucopolysaccharides, stimulates hepatic synthesis of cholesterol and fatty acids, and is a cofactor in many enzymes, including arginase and alkaline phosphatase in the liver. (From AMA Drug Evaluations Annual 1992, p2035)
Orthophosphate
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
MagnesiumA metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION.
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
D-Glutamate
glutamate
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
CycloserineAntibiotic substance produced by Streptomyces garyphalus.
uridine diphosphate n-acetylmuramic acidA nucleoside diphosphate sugar which is formed from UDP-N-acetylglucosamine and phosphoenolpyruvate. It serves as the building block upon which peptidoglycan is formed.
Flavin-Adenine DinucleotideA condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase. (Lehninger, Principles of Biochemistry, 1982, p972)