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UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-diaminopimelate containing)

Proteins (17)

ProteinSynonymsTaxonomy
UDP-N-acetylglucosamine 1-carboxyvinyltransferaseEC 2.5.1.7; Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPTEscherichia coli K-12
Glutamate racemaseEC 5.1.1.3Mycobacterium tuberculosis H37Rv
D-alanine--D-alanine ligase BEC 6.3.2.4; D-Ala-D-Ala ligase B; D-alanylalanine synthetase BEscherichia coli K-12
Glutamate racemaseEC 5.1.1.3Escherichia coli K-12
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligaseEC 6.3.2.10; D-alanyl-D-alanine-adding enzyme; UDP-MurNAc-pentapeptide synthetaseEscherichia coli K-12
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligaseEC 6.3.2.13; Meso-A2pm-adding enzyme; Meso-diaminopimelate-adding enzyme; UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase; UDP-MurNAc-tripeptide synthetase; UDP-N-acetylmuramyl-tripeptide synthetaseEscherichia coli K-12
UDP-N-acetylenolpyruvoylglucosamine reductaseEC 1.3.1.98; UDP-N-acetylmuramate dehydrogenaseEscherichia coli K-12
UDP-N-acetylmuramoylalanine--D-glutamate ligaseEC 6.3.2.9; D-glutamic acid-adding enzyme; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetaseEscherichia coli K-12
UDP-N-acetylmuramate--L-alanine ligaseEC 6.3.2.8; UDP-N-acetylmuramoyl-L-alanine synthetaseEscherichia coli K-12
D-alanine--D-alanine ligaseEC 6.3.2.4; D-Ala-D-Ala ligase; D-alanine:D-alanine ligase; D-alanylalanine synthetaseMycobacterium tuberculosis H37Rv
UDP-N-acetylglucosamine 1-carboxyvinyltransferaseEC 2.5.1.7; Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPTMycobacterium tuberculosis H37Rv
UDP-N-acetylmuramate--L-alanine ligaseEC 6.3.2.8; UDP-N-acetylmuramoyl-L-alanine synthetaseMycobacterium tuberculosis H37Rv
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligaseEC 6.3.2.10; D-alanyl-D-alanine-adding enzyme; UDP-MurNAc-pentapeptide synthetaseMycobacterium tuberculosis H37Rv
UDP-N-acetylmuramoylalanine--D-glutamate ligaseEC 6.3.2.9; D-glutamic acid-adding enzyme; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetaseMycobacterium tuberculosis H37Rv
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligaseEC 6.3.2.13; Meso-A2pm-adding enzyme; Meso-diaminopimelate-adding enzyme; UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase; UDP-MurNAc-tripeptide synthetase; UDP-N-acetylmuramyl-tripeptide synthetaseMycobacterium tuberculosis H37Rv
D-alanine--D-alanine ligase AEC 6.3.2.4; D-Ala-D-Ala ligase A; D-alanylalanine synthetase AEscherichia coli K-12
UDP-N-acetylenolpyruvoylglucosamine reductase Mycobacterium tuberculosis H37Rv

Compounds (18)

CompoundDescription
hydronium ion
uridine diphosphateA uracil nucleotide containing a pyrophosphate group esterified to C5 of the sugar moiety.
Ammonium
ManganeseA trace element with atomic symbol Mn, atomic number 25, and atomic weight 54.94. It is concentrated in cell mitochondria, mostly in the pituitary gland, liver, pancreas, kidney, and bone, influences the synthesis of mucopolysaccharides, stimulates hepatic synthesis of cholesterol and fatty acids, and is a cofactor in many enzymes, including arginase and alkaline phosphatase in the liver. (From AMA Drug Evaluations Annual 1992, p2035)
Orthophosphate
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
potassiumAn element in the alkali group of metals with an atomic symbol K, atomic number 19, and atomic weight 39.10. It is the chief cation in the intracellular fluid of muscle and other cells. Potassium ion is a strong electrolyte that plays a significant role in the regulation of fluid volume and maintenance of the WATER-ELECTROLYTE BALANCE.
MagnesiumA metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION.
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
D-Glutamate
glutamate
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
beta-chloro-D-alanine
CycloserineAntibiotic substance produced by Streptomyces garyphalus.
uridine diphosphate n-acetylmuramic acidA nucleoside diphosphate sugar which is formed from UDP-N-acetylglucosamine and phosphoenolpyruvate. It serves as the building block upon which peptidoglycan is formed.
Flavin-Adenine DinucleotideA condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase. (Lehninger, Principles of Biochemistry, 1982, p972)
bromoacetate