| Protein | Synonyms | Taxonomy |
|---|
| Catalase | EC 1.11.1.6 | Homo sapiens (human) |
| Cytochrome P450 4B1 | EC 1.14.14.1; CYPIVB1; Cytochrome P450-HP | Homo sapiens (human) |
| Cytochrome P450 2F1 | EC 1.14.14.1; CYPIIF1 | Homo sapiens (human) |
| Trifunctional enzyme subunit alpha, mitochondrial | 78 kDa gastrin-binding protein; Monolysocardiolipin acyltransferase; 2.3.1.-; TP-alpha | Homo sapiens (human) |
| 4-trimethylaminobutyraldehyde dehydrogenase | TMABA-DH; TMABALDH; EC 1.2.1.47; Aldehyde dehydrogenase E3 isozyme; Aldehyde dehydrogenase family 9 member A1; 1.2.1.3; Gamma-aminobutyraldehyde dehydrogenase; 1.2.1.19; R-aminobutyraldehyde dehydrogenase | Homo sapiens (human) |
| Aldehyde dehydrogenase family 3 member A2 | EC 1.2.1.3; EC 1.2.1.94; Aldehyde dehydrogenase 10; Fatty aldehyde dehydrogenase; Microsomal aldehyde dehydrogenase | Homo sapiens (human) |
| Cytochrome P450 4F8 | EC 1.14.14.1; CYPIVF8 | Homo sapiens (human) |
| 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase | EC 4.1.1.45; Picolinate carboxylase | Homo sapiens (human) |
| Glutaryl-CoA dehydrogenase, mitochondrial | GCD; EC 1.3.8.6 | Homo sapiens (human) |
| 3-hydroxyacyl-CoA dehydrogenase type-2 | EC 1.1.1.35; 17-beta-estradiol 17-dehydrogenase; 1.1.1.62; 2-methyl-3-hydroxybutyryl-CoA dehydrogenase; MHBD; 3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+)); 1.1.1.239; 3-hydroxy-2-methylbutyryl-CoA dehydrogenase; 1.1.1.178; 3-hydroxyacyl-CoA deh | Homo sapiens (human) |
| Cytochrome P450 1A2 | EC 1.14.14.1; CYPIA2; Cholesterol 25-hydroxylase; Cytochrome P(3)450; Cytochrome P450 4; Cytochrome P450-P3; Hydroperoxy icosatetraenoate dehydratase; 4.2.1.152 | Homo sapiens (human) |
| Cytochrome P450 3A4 | EC 1.14.14.1; 1,4-cineole 2-exo-monooxygenase; 1,8-cineole 2-exo-monooxygenase; 1.14.14.56; Albendazole monooxygenase (sulfoxide-forming); 1.14.14.73; Albendazole sulfoxidase; CYPIIIA3; CYPIIIA4; Cholesterol 25-hydroxylase; Cytochrome P450 3A3; Cytochrome | Homo sapiens (human) |
| Cytochrome P450 2C8 | EC 1.14.14.1; CYPIIC8; Cytochrome P450 IIC2; Cytochrome P450 MP-12; Cytochrome P450 MP-20; Cytochrome P450 form 1; S-mephenytoin 4-hydroxylase | Homo sapiens (human) |
| Cytochrome P450 2D6 | EC 1.14.14.-; CYPIID6; Cholesterol 25-hydroxylase; Cytochrome P450-DB1; Debrisoquine 4-hydroxylase | Homo sapiens (human) |
| Cytochrome P450 2C9 | EC 1.14.14.1; (R)-limonene 6-monooxygenase; 1.14.14.53; (S)-limonene 6-monooxygenase; 1.14.14.51; (S)-limonene 7-monooxygenase; 1.14.14.52; CYPIIC9; Cholesterol 25-hydroxylase; Cytochrome P-450MP; Cytochrome P450 MP-4; Cytochrome P450 MP-8; Cytochrome P45 | Homo sapiens (human) |
| Cytochrome P450 2B6 | EC 1.14.13.-; 1,4-cineole 2-exo-monooxygenase; CYPIIB6; Cytochrome P450 IIB1 | Homo sapiens (human) |
| Cytochrome P450 3A5 | EC 1.14.14.1; CYPIIIA5; Cytochrome P450-PCN3 | Homo sapiens (human) |
| Amine oxidase [flavin-containing] A | EC 1.4.3.4; Monoamine oxidase type A; MAO-A | Homo sapiens (human) |
| Cytochrome P450 2C19 | EC 1.14.14.1; (R)-limonene 6-monooxygenase; 1.14.14.53; (S)-limonene 6-monooxygenase; 1.14.14.51; (S)-limonene 7-monooxygenase; 1.14.14.52; CYPIIC17; CYPIIC19; Cytochrome P450-11A; Cytochrome P450-254C; Fenbendazole monooxygenase (4'-hydroxylating); 1.14. | Homo sapiens (human) |
| Enoyl-CoA hydratase, mitochondrial | EC 4.2.1.17; Enoyl-CoA hydratase 1; Short-chain enoyl-CoA hydratase; SCEH | Homo sapiens (human) |
| Cytochrome P450 2A13 | EC 1.14.14.1; CYPIIA13 | Homo sapiens (human) |
| Cytochrome P450 1A1 | CYPIA1; EC 1.14.14.1; Cytochrome P450 form 6; Cytochrome P450-C; Cytochrome P450-P1; Hydroperoxy icosatetraenoate dehydratase; 4.2.1.152 | Homo sapiens (human) |
| Cytochrome P450 2E1 | EC 1.14.14.1; 4-nitrophenol 2-hydroxylase; 1.14.13.n7; CYPIIE1; Cytochrome P450-J | Homo sapiens (human) |
| Cytochrome P450 2A6 | EC 1.14.13.-; 1,4-cineole 2-exo-monooxygenase; CYPIIA6; Coumarin 7-hydroxylase; Cytochrome P450 IIA3; Cytochrome P450(I) | Homo sapiens (human) |
| Aromatase | EC 1.14.14.14; CYPXIX; Cytochrome P-450AROM; Cytochrome P450 19A1; Estrogen synthase | Homo sapiens (human) |
| Indoleamine 2,3-dioxygenase 1 | IDO-1; EC 1.13.11.52; Indoleamine-pyrrole 2,3-dioxygenase | Homo sapiens (human) |
| Cytochrome P450 3A7 | EC 1.14.14.1; CYPIIIA7; Cytochrome P450-HFLA; P450HLp2 | Homo sapiens (human) |
| Amine oxidase [flavin-containing] B | EC 1.4.3.4; Monoamine oxidase type B; MAO-B | Homo sapiens (human) |
| E3 ubiquitin-protein ligase Mdm2 | EC 2.3.2.27; Double minute 2 protein; Hdm2; Oncoprotein Mdm2; RING-type E3 ubiquitin transferase Mdm2; p53-binding protein Mdm2 | Homo sapiens (human) |
| Cytochrome P450 1B1 | EC 1.14.14.1; CYPIB1; Hydroperoxy icosatetraenoate dehydratase; 4.2.1.152 | Homo sapiens (human) |
| Cytochrome P450 2A7 | EC 1.14.14.1; CYPIIA7; Cytochrome P450 IIA4 | Homo sapiens (human) |
| Cytochrome P450 4F12 | EC 1.14.14.1; CYPIVF12 | Homo sapiens (human) |
| Retinal dehydrogenase 1 | RALDH 1; RalDH1; EC 1.2.1.-; EC 1.2.1.36; ALDH-E1; ALHDII; Aldehyde dehydrogenase family 1 member A1; Aldehyde dehydrogenase, cytosolic | Homo sapiens (human) |
| Aldehyde dehydrogenase, mitochondrial | EC 1.2.1.3; ALDH class 2; ALDH-E2; ALDHI | Homo sapiens (human) |
| Tryptophan 5-hydroxylase 1 | EC 1.14.16.4; Tryptophan 5-monooxygenase 1 | Homo sapiens (human) |
| Kynureninase | EC 3.7.1.3; L-kynurenine hydrolase | Homo sapiens (human) |
| Cytochrome P450 3A43 | EC 1.14.14.1 | Homo sapiens (human) |
| Serotonin N-acetyltransferase | Serotonin acetylase; EC 2.3.1.87; Aralkylamine N-acetyltransferase; AA-NAT | Homo sapiens (human) |
| Retina-specific copper amine oxidase | RAO; EC 1.4.3.21; Amine oxidase [copper-containing]; Semicarbazide-sensitive amine oxidase; SSAO | Homo sapiens (human) |
| Tryptophan 2,3-dioxygenase | TDO; EC 1.13.11.11; Tryptamin 2,3-dioxygenase; Tryptophan oxygenase; TO; TRPO; Tryptophan pyrrolase; Tryptophanase | Homo sapiens (human) |
| Cytochrome P450 2J2 | EC 1.14.14.-; Albendazole monooxygenase (hydroxylating); 1.14.14.74; Albendazole monooxygenase (sulfoxide-forming); 1.14.14.73; Arachidonic acid epoxygenase; CYPIIJ2; Hydroperoxy icosatetraenoate isomerase; 5.4.4.7 | Homo sapiens (human) |
| Aldehyde oxidase | EC 1.2.3.1; Aldehyde oxidase 1; Azaheterocycle hydroxylase; 1.17.3.- | Homo sapiens (human) |
| Membrane primary amine oxidase | EC 1.4.3.21; Copper amine oxidase; HPAO; Semicarbazide-sensitive amine oxidase; SSAO; Vascular adhesion protein 1; VAP-1 | Homo sapiens (human) |
| Cytochrome P450 2C18 | EC 1.14.14.1; CYPIIC18; Cytochrome P450-6b/29c | Homo sapiens (human) |
| Cytochrome P450 4F11 | CYPIVF11; EC 1.14.14.1; 3-hydroxy fatty acids omega-hydroxylase CYP4F11; Docosahexaenoic acid omega-hydroxylase; 1.14.14.79; Long-chain fatty acid omega-monooxygenase; 1.14.14.80; Phylloquinone omega-hydroxylase CYP4F11; 1.14.14.78 | Homo sapiens (human) |
| Kynurenine formamidase | KFA; KFase; EC 3.5.1.9; Arylformamidase; N-formylkynurenine formamidase; FKF | Homo sapiens (human) |
| Peroxisomal bifunctional enzyme | PBE; PBFE; L-bifunctional protein; LBP; Multifunctional enzyme 1; MFE1 | Homo sapiens (human) |
| Kynurenine 3-monooxygenase | EC 1.14.13.9; Kynurenine 3-hydroxylase | Homo sapiens (human) |
| Retinal dehydrogenase 2 | RALDH 2; RalDH2; EC 1.2.1.36; Aldehyde dehydrogenase family 1 member A2; Retinaldehyde-specific dehydrogenase type 2; RALDH(II) | Homo sapiens (human) |
| Indolethylamine N-methyltransferase | Indolamine N-methyltransferase; EC 2.1.1.49; EC 2.1.1.96; Aromatic alkylamine N-methyltransferase; Amine N-methyltransferase; Arylamine N-methyltransferase; Thioether S-methyltransferase; TEMT | Homo sapiens (human) |
| Amiloride-sensitive amine oxidase [copper-containing] | DAO; Diamine oxidase; EC 1.4.3.22; Amiloride-binding protein 1; Amine oxidase copper domain-containing protein 1; Histaminase; Kidney amine oxidase; KAO | Homo sapiens (human) |
| Aromatic-L-amino-acid decarboxylase | AADC; EC 4.1.1.28; DOPA decarboxylase; DDC | Homo sapiens (human) |
| Acetyl-CoA acetyltransferase, mitochondrial | EC 2.3.1.9; Acetoacetyl-CoA thiolase; T2 | Homo sapiens (human) |
| Aldehyde dehydrogenase X, mitochondrial | EC 1.2.1.3; Aldehyde dehydrogenase 5; Aldehyde dehydrogenase family 1 member B1 | Homo sapiens (human) |
| 3-hydroxyanthranilate 3,4-dioxygenase | EC 1.13.11.6; 3-hydroxyanthranilate oxygenase; 3-HAO; h3HAO; 3-hydroxyanthranilic acid dioxygenase; HAD | Homo sapiens (human) |
| Ubiquitin-protein ligase E3A | EC 2.3.2.26; E6AP ubiquitin-protein ligase; HECT-type ubiquitin transferase E3A; Human papillomavirus E6-associated protein; Oncogenic protein-associated protein E6-AP; Renal carcinoma antigen NY-REN-54 | Homo sapiens (human) |
| Acetylserotonin O-methyltransferase | EC 2.1.1.4; Hydroxyindole O-methyltransferase; HIOMT | Homo sapiens (human) |
| Acetyl-CoA acetyltransferase, cytosolic | EC 2.3.1.9; Acetyl-CoA transferase-like protein; Cytosolic acetoacetyl-CoA thiolase | Homo sapiens (human) |
| Tryptophan--tRNA ligase, cytoplasmic | EC 6.1.1.2; Interferon-induced protein 53; IFP53; Tryptophanyl-tRNA synthetase; TrpRS; hWRS | Homo sapiens (human) |
| Alpha-aminoadipic semialdehyde dehydrogenase | Alpha-AASA dehydrogenase; EC 1.2.1.31; Aldehyde dehydrogenase family 7 member A1; 1.2.1.3; Antiquitin-1; Betaine aldehyde dehydrogenase; 1.2.1.8; Delta1-piperideine-6-carboxylate dehydrogenase; P6c dehydrogenase | Homo sapiens (human) |
| Transcriptional repressor NF-X1 | EC 2.3.2.-; Nuclear transcription factor, X box-binding protein 1 | Homo sapiens (human) |
| Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | HCDH; EC 1.1.1.35; Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase; Short-chain 3-hydroxyacyl-CoA dehydrogenase | Homo sapiens (human) |
| E3 ubiquitin-protein ligase RNF25 | EC 2.3.2.27; RING finger protein 25; RING-type E3 ubiquitin transferase RNF25 | Homo sapiens (human) |
| Tryptophan--tRNA ligase, mitochondrial | EC 6.1.1.2; (Mt)TrpRS; Tryptophanyl-tRNA synthetase; TrpRS | Homo sapiens (human) |
| Compound | Description |
|---|
| phosphoric acid | concise etchant is 37% H3PO4 |
| diphosphoric acid | |
| sapropterin | RN given refers to parent cpd; co-factor required for catalytic activity of nitric oxide synthases |
| ammonium hydroxide | The hydroxy salt of ammonium ion. It is formed when AMMONIA reacts with water molecules in solution. |
| Carbon Dioxide | A colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals. |
| s-adenosylmethionine | Physiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed) |
| NADH | |
| 5-hydroxytryptophan | The immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant. |
| Adenosine Triphosphate | An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter. |
| adenosine diphosphate | Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position. |
| adenosine monophosphate | Adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position. |
| tryptophan | An essential amino acid that is necessary for normal growth in infants and for NITROGEN balance in adults. It is a precursor of INDOLE ALKALOIDS in plants. It is a precursor of SEROTONIN (hence its use as an antidepressant and sleep aid). It can be a precursor to NIACIN, albeit inefficiently, in mammals. |
| glycine | A non-essential amino acid. It is found primarily in gelatin and silk fibroin and used therapeutically as a nutrient. It is also a fast inhibitory neurotransmitter. |
| Hydrogen Peroxide | A strong oxidizing agent used in aqueous solution as a ripening agent, bleach, and topical anti-infective. It is relatively unstable and solutions deteriorate over time unless stabilized by the addition of acetanilide or similar organic materials. |
| melatonin | A biogenic amine that is found in animals and plants. In mammals, melatonin is produced by the PINEAL GLAND. Its secretion increases in darkness and decreases during exposure to light. Melatonin is implicated in the regulation of SLEEP, mood, and REPRODUCTION. Melatonin is also an effective antioxidant. |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| Oxygen | An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration. |
| 4a-carbinolamine tetrahydrobiopterin | structure given in first source |
| quinolinic acid | A metabolite of tryptophan with a possible role in neurodegenerative disorders. Elevated CSF levels of quinolinic acid are correlated with the severity of neuropsychological deficits in patients who have AIDS. |
| tryptamine | RN given refers to parent cpd |
| 3-hydroxykynurenine, (L)-isomer | |
| kynurenine | A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway. |
| hydroxyindoleacetic acid | |
| 6-hydroxymelatonin | |
| anthranilic acid | RN given refers to parent cpd; structure in Negwer, 5th ed, #565 |
| formic acid | RN given refers to parent cpd |
| glutaryl-coenzyme a | |
| n'-formylkynurenine | a photochemical breakdown product of tryptophan in proteins; RN given refers to parent cpd without isomeric designation |
| Serotonin | A biochemical messenger and regulator, synthesized from the essential amino acid L-TRYPTOPHAN. In humans it is found primarily in the central nervous system, gastrointestinal tract, and blood platelets. Serotonin mediates several important physiological functions including neurotransmission, gastrointestinal motility, hemostasis, and cardiovascular integrity. Multiple receptor families (RECEPTORS, SEROTONIN) explain the broad physiological actions and distribution of this biochemical mediator. |
| crotonyl-coenzyme a | |
| NAD | A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed) |
| alanine | A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM. |
| n-methyltryptamine | RN given refers to parent cpd |
| indole-3-acetaldehyde | |
| indoleacetic acid | RN given refers to unlabeled parent cpd; structure in Merck Index, 9th ed, #4841 |
| 3-hydroxyanthranilic acid | An oxidation product of tryptophan metabolism. It may be a free radical scavenger and a carcinogen. |
| 3-hydroxybutyryl-coenzyme A, (S)-isomer | |
| cinnabarinic acid | structure |
| n-methylserotonin | RN given refers to parent cpd |
| 5-hydroxykynuramine | RN given refers to parent cpd; structure |
| 5-methoxyindoleacetic acid | serotonin metabolite |
| s-adenosylhomocysteine | 5'-S-(3-Amino-3-carboxypropyl)-5'-thioadenosine. Formed from S-adenosylmethionine after transmethylation reactions. |
| acetyl coenzyme a | Acetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent. |
| creolin | from refined coal tar oils |
| hydroxyindoleacetaldehyde | |
| coenzyme a | |
| n-acetylserotonin | |
| acetoacetyl coa | |