Page last updated: 2024-10-06

Triosephosphate Isomerase Deficiency

Proteins (22)

ProteinSynonymsTaxonomy
Bisphosphoglycerate mutaseBPGM; EC 5.4.2.4; 2,3-bisphosphoglycerate mutase, erythrocyte; 2,3-bisphosphoglycerate synthase; 5.4.2.11; 2,3-diphosphoglycerate mutase; DPGM; BPG-dependent PGAMHomo sapiens (human)
Fructose-bisphosphate aldolase AEC 4.1.2.13; Lung cancer antigen NY-LU-1; Muscle-type aldolaseHomo sapiens (human)
Glyceraldehyde-3-phosphate dehydrogenaseGAPDH; EC 1.2.1.12; Peptidyl-cysteine S-nitrosylase GAPDH; 2.6.99.-Homo sapiens (human)
L-lactate dehydrogenase A chainLDH-A; EC 1.1.1.27; Cell proliferation-inducing gene 19 protein; LDH muscle subunit; LDH-M; Renal carcinoma antigen NY-REN-59Homo sapiens (human)
Solute carrier family 2, facilitated glucose transporter member 2Glucose transporter type 2, liver; GLUT-2Homo sapiens (human)
Glucose-6-phosphate isomeraseGPI; EC 5.3.1.9; Autocrine motility factor; AMF; Neuroleukin; NLK; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI; Sperm antigen 36; SA-36Homo sapiens (human)
Fructose-1,6-bisphosphatase 1FBPase 1; EC 3.1.3.11; D-fructose-1,6-bisphosphate 1-phosphohydrolase 1; Liver FBPaseHomo sapiens (human)
Glucose-6-phosphataseG-6-Pase; G6Pase; EC 3.1.3.9; Glucose-6-phosphatase alpha; G6Pase-alphaHomo sapiens (human)
Triosephosphate isomeraseTIM; EC 5.3.1.1; Methylglyoxal synthase; 4.2.3.3; Triose-phosphate isomeraseHomo sapiens (human)
Alpha-enolaseEC 4.2.1.11; 2-phospho-D-glycerate hydro-lyase; C-myc promoter-binding protein; Enolase 1; MBP-1; MPB-1; Non-neural enolase; NNE; Phosphopyruvate hydratase; Plasminogen-binding proteinHomo sapiens (human)
Malate dehydrogenase, mitochondrialEC 1.1.1.37Homo sapiens (human)
Hexokinase-2EC 2.7.1.1; Hexokinase type II; HK II; Hexokinase-B; Muscle form hexokinaseHomo sapiens (human)
Phosphoglycerate mutase 1EC 5.4.2.11; EC 5.4.2.4; BPG-dependent PGAM 1; Phosphoglycerate mutase isozyme B; PGAM-BHomo sapiens (human)
Phosphoenolpyruvate carboxykinase, cytosolic [GTP]PEPCK-C; EC 4.1.1.32; Serine-protein kinase PCK1; 2.7.11.-Homo sapiens (human)
Galactose mutarotaseEC 5.1.3.3; Aldose 1-epimeraseHomo sapiens (human)
Glucose-6-phosphate exchanger SLC37A4Glucose-5-phosphate transporter; Glucose-6-phosphate translocase; Solute carrier family 37 member 4; Transformation-related gene 19 protein; TRG-19Homo sapiens (human)
Pantothenate kinase 1hPanK; hPanK1; EC 2.7.1.33; Pantothenic acid kinase 1Homo sapiens (human)
Pyruvate carboxylase, mitochondrialEC 6.4.1.1; Pyruvic carboxylase; PCBHomo sapiens (human)
Phosphoglucomutase-1PGM 1; EC 5.4.2.2; Glucose phosphomutase 1Homo sapiens (human)
Phosphoglycerate mutase 2EC 5.4.2.11; EC 5.4.2.4; BPG-dependent PGAM 2; Muscle-specific phosphoglycerate mutase; Phosphoglycerate mutase isozyme M; PGAM-MHomo sapiens (human)
Mitochondrial 2-oxoglutarate/malate carrier proteinOGCP; Solute carrier family 25 member 11Homo sapiens (human)
Mitochondrial pyruvate carrier 1Brain protein 44-like proteinHomo sapiens (human)

Compounds (28)

CompoundDescription
phosphoric acidconcise etchant is 37% H3PO4
hydronium ion
pyruvic acidAn intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
Orthophosphate
l-lactic acid
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
NADH
malic acid
GlucoseA primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient replacement.
Adenosine TriphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
glucose, (beta-d)-isomer
hydrogen carbonate
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
phosphoenolpyruvateA monocarboxylic acid anion derived from selective deprotonation of the carboxy group of phosphoenolpyruvic acid. It is a metabolic intermediate in GLYCOLYSIS; GLUCONEOGENESIS; and other pathways.
glucose-1-phosphateRN given refers to (alpha-D-Glc)-isomer
2-phosphoglycerate, (R)-isomer
alpha-ketoglutaric acid
NADA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
Glucose-6-PhosphateAn ester of glucose with phosphoric acid, made in the course of glucose metabolism by mammalian and other cells. It is a normal constituent of resting muscle and probably is in constant equilibrium with fructose-6-phosphate. (Stedman, 26th ed)
dihydroxyacetone phosphateAn important intermediate in lipid biosynthesis and in glycolysis.
glycerate 1,3-biphosphate
fructose-6-phosphateRN given refers to parent cpd with unspecified isomeric designation
3-phosphoglycerate
Glyceraldehyde 3-PhosphateAn aldotriose which is an important intermediate in glycolysis and in tryptophan biosynthesis.
oxaloacetic acidA dicarboxylic acid ketone that is an important metabolic intermediate of the CITRIC ACID CYCLE. It can be converted to ASPARTIC ACID by ASPARTATE TRANSAMINASE.
2,3-Diphosphoglycerate, (D)-Isomer
glucoseA primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient replacement.