Page last updated: 2024-10-06

Transport of bile salts and organic acids, metal ions and amine compounds

Proteins (49)

ProteinSynonymsTaxonomy
Basigin5F7; Collagenase stimulatory factor; Extracellular matrix metalloproteinase inducer; EMMPRIN; Hepatoma-associated antigen; HAb18G; Leukocyte activation antigen M6; OK blood group antigen; Tumor cell-derived collagenase stimulatory factor; TCSFHomo sapiens (human)
Runt-related transcription factor 1Acute myeloid leukemia 1 protein; Core-binding factor subunit alpha-2; CBF-alpha-2; Oncogene AML-1; Polyomavirus enhancer-binding protein 2 alpha B subunit; PEA2-alpha B; PEBP2-alpha B; SL3-3 enhancer factor 1 alpha B subunit; SL3/AKV core-binding factor Homo sapiens (human)
Solute carrier family 13 member 5Na(+)/citrate cotransporter; NaCT; Sodium-coupled citrate transporter; Sodium-dependent citrate transporterHomo sapiens (human)
Solute carrier family 13 member 3Na(+)/dicarboxylate cotransporter 3; NaDC-3; hNaDC3; Sodium-dependent high-affinity dicarboxylate transporter 2Homo sapiens (human)
Solute carrier family 22 member 4Ergothioneine transporter; ET transporter; Organic cation/carnitine transporter 1Homo sapiens (human)
Sodium- and chloride-dependent taurine transporterSolute carrier family 6 member 6Homo sapiens (human)
Sodium/myo-inositol cotransporter 2Na(+)/myo-inositol cotransporter 2; Sodium-dependent glucose cotransporter; Sodium/glucose cotransporter KST1; Sodium/myo-inositol transporter 2; SMIT2; Solute carrier family 5 member 11Homo sapiens (human)
Sodium-dependent noradrenaline transporter Norepinephrine transporter; NET; Solute carrier family 6 member 2Homo sapiens (human)
Sodium- and chloride-dependent betaine transporterBGT-1; Na(+)/Cl(-) betaine/GABA transporter; Solute carrier family 6 member 12Homo sapiens (human)
Sodium-dependent dopamine transporter DA transporter; DAT; Solute carrier family 6 member 3Homo sapiens (human)
Sodium/myo-inositol cotransporterNa(+)/myo-inositol cotransporter; Sodium/myo-inositol transporter 1; SMIT1; Solute carrier family 5 member 3Homo sapiens (human)
Monocarboxylate transporter 1MCT 1; Solute carrier family 16 member 1Homo sapiens (human)
Solute carrier family 22 member 12Organic anion transporter 4-like protein; Renal-specific transporter; RST; Urate anion exchanger 1Homo sapiens (human)
High affinity choline transporter 1Hemicholinium-3-sensitive choline transporter; CHT; Solute carrier family 5 member 7Homo sapiens (human)
Natural resistance-associated macrophage protein 2NRAMP 2; Divalent cation transporter 1; Divalent metal transporter 1; DMT-1; Solute carrier family 11 member 2Homo sapiens (human)
Monocarboxylate transporter 2MCT 2; Solute carrier family 16 member 7Homo sapiens (human)
Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+)Amino acid transporter ATB0+; Solute carrier family 6 member 14Homo sapiens (human)
Monocarboxylate transporter 4MCT 4; Solute carrier family 16 member 3Homo sapiens (human)
Solute carrier family 22 member 3Extraneuronal monoamine transporter; EMT; Organic cation transporter 3Homo sapiens (human)
Natural resistance-associated macrophage protein 1NRAMP 1; Solute carrier family 11 member 1Homo sapiens (human)
Zinc transporter 8ZnT-8; Solute carrier family 30 member 8Homo sapiens (human)
Sodium-dependent proline transporterSolute carrier family 6 member 7Homo sapiens (human)
Sodium-dependent neutral amino acid transporter B(0)AT2Sodium- and chloride-dependent neurotransmitter transporter NTT73; Sodium-coupled branched-chain amino-acid transporter 1; Solute carrier family 6 member 15; Transporter v7-3Homo sapiens (human)
Solute carrier family 40 member 1Ferroportin-1; Iron-regulated transporter 1Homo sapiens (human)
Solute carrier family 13 member 2Na(+)/dicarboxylate cotransporter 1; NaDC-1; Renal sodium/dicarboxylate cotransporterHomo sapiens (human)
High affinity copper uptake protein 1Copper transporter 1; hCTR1; Solute carrier family 31 member 1Homo sapiens (human)
Monocarboxylate transporter 3MCT 3; Solute carrier family 16 member 8Homo sapiens (human)
Zinc transporter SLC39A7Histidine-rich membrane protein Ke4; Really interesting new gene 5 protein; Solute carrier family 39 member 7; Zrt-, Irt-like protein 7; ZIP7Homo sapiens (human)
CeruloplasminEC 1.16.3.1; FerroxidaseHomo sapiens (human)
Zinc transporter ZIP5Solute carrier family 39 member 5; Zrt- and Irt-like protein 5; ZIP-5Homo sapiens (human)
Regulatory solute carrier protein family 1 member 1Transporter regulator RS1; hRS1Homo sapiens (human)
Ammonium transporter Rh type BRhesus blood group family type B glycoprotein; Rh family type B glycoprotein; Rh type B glycoproteinHomo sapiens (human)
Ammonium transporter Rh type AErythrocyte membrane glycoprotein Rh50; Erythrocyte plasma membrane 50 kDa glycoprotein; Rh50A; Rhesus blood group family type A glycoprotein; Rh family type A glycoprotein; Rh type A glycoprotein; Rhesus blood group-associated ammonia channel; Rhesus bloHomo sapiens (human)
Solute carrier family 10 member 6Sodium-dependent organic anion transporterHomo sapiens (human)
Sodium-dependent neutral amino acid transporter B(0)AT1Solute carrier family 6 member 19; System B(0) neutral amino acid transporter AT1Homo sapiens (human)
EmbiginHomo sapiens (human)
Zinc transporter 10ZnT-10; Manganese transporter SLC30A10; Solute carrier family 30 member 10Homo sapiens (human)
Zinc transporter 5ZnT-5; Solute carrier family 30 member 5; ZnT-like transporter 1; hZTL1Homo sapiens (human)
Solute carrier family 22 member 18Beckwith-Wiedemann syndrome chromosomal region 1 candidate gene A protein; Efflux transporter-like protein; Imprinted multi-membrane-spanning polyspecific transporter-related protein 1; Organic cation transporter-like protein 2; ORCTL-2; Solute carrier faHomo sapiens (human)
Inactive sodium-dependent neutral amino acid transporter B(0)AT3Sodium- and chloride-dependent transporter XTRP2; Solute carrier family 6 member 18; System B(0) neutral amino acid transporter AT3Homo sapiens (human)
Proton myo-inositol cotransporterH(+)-myo-inositol cotransporter; Hmit; H(+)-myo-inositol symporter; Solute carrier family 2 member 13Homo sapiens (human)
HephaestinEC 1.-.-.-Homo sapiens (human)
Zinc transporter 2ZnT-2; Solute carrier family 30 member 2Homo sapiens (human)
Solute carrier family 13 member 1Renal sodium/sulfate cotransporter; Na(+)/sulfate cotransporter; hNaSi-1Homo sapiens (human)
Sodium- and chloride-dependent transporter XTRP3Sodium/imino-acid transporter 1; Solute carrier family 6 member 20; Transporter rB21A homologHomo sapiens (human)
Ammonium transporter Rh type CRh glycoprotein kidney; Rhesus blood group family type C glycoprotein; Rh family type C glycoprotein; Rh type C glycoprotein; Tumor-related protein DRC2Homo sapiens (human)
Solute carrier family 13 member 4Na(+)/sulfate cotransporter SUT-1; NaS2Homo sapiens (human)
Zinc transporter ZIP10Solute carrier family 39 member 10; Zrt- and Irt-like protein 10; ZIP-10Homo sapiens (human)
Zinc transporter 1ZnT-1; Solute carrier family 30 member 1Homo sapiens (human)

Compounds (23)

CompoundDescription
hydronium ion
l-lactic acid
ureaA compound formed in the liver from ammonia produced by the deamination of amino acids. It is the principal end product of protein catabolism and constitutes about one half of the total urinary solids.
Succinate
Ammonium
CopperA heavy metal trace element with the atomic symbol Cu, atomic number 29, and atomic weight 63.55.
CopperA heavy metal trace element with the atomic symbol Cu, atomic number 29, and atomic weight 63.55.
ironA metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN.
ManganeseA trace element with atomic symbol Mn, atomic number 25, and atomic weight 54.94. It is concentrated in cell mitochondria, mostly in the pituitary gland, liver, pancreas, kidney, and bone, influences the synthesis of mucopolysaccharides, stimulates hepatic synthesis of cholesterol and fatty acids, and is a cofactor in many enzymes, including arginase and alkaline phosphatase in the liver. (From AMA Drug Evaluations Annual 1992, p2035)
cholineA basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism.
citric acid, anhydrous
chlorineAn element with atomic symbol Cl, atomic number 17, and atomic weight 35, and member of the halogen family.
ZincA metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn.
Dopamine Hydrochloride
MagnesiumA metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION.
inositolAn isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
SodiumA member of the alkali group of metals. It has the atomic symbol Na, atomic number 11, and atomic weight 23.
uric acidAn oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
alpha-Ketoglutarate
carnitineA constituent of STRIATED MUSCLE and LIVER. It is an amino acid derivative and an essential cofactor for fatty acid metabolism.
SerotoninA biochemical messenger and regulator, synthesized from the essential amino acid L-TRYPTOPHAN. In humans it is found primarily in the central nervous system, gastrointestinal tract, and blood platelets. Serotonin mediates several important physiological functions including neurotransmission, gastrointestinal motility, hemostasis, and cardiovascular integrity. Multiple receptor families (RECEPTORS, SEROTONIN) explain the broad physiological actions and distribution of this biochemical mediator.
taurolithocholic acid 3-sulfate
ergothioneineA naturally occurring metabolite of HISTIDINE that has antioxidant properties.