Page last updated: 2024-10-06

Transfer of Acetyl Groups into Mitochondria

Proteins (9)

ProteinSynonymsTaxonomy
ATP-citrate synthaseEC 2.3.3.8; ATP-citrate (pro-S-)-lyase; ACL; Citrate cleavage enzymeHomo sapiens (human)
Pyruvate dehydrogenase E1 component subunit beta, mitochondrialPDHE1-B; EC 1.2.4.1Homo sapiens (human)
NADP-dependent malic enzymeNADP-ME; EC 1.1.1.40; Malic enzyme 1Homo sapiens (human)
Malate dehydrogenase, cytoplasmicEC 1.1.1.37; Cytosolic malate dehydrogenase; Diiodophenylpyruvate reductase; 1.1.1.96Homo sapiens (human)
Pyruvate carboxylase, mitochondrialEC 6.4.1.1; Pyruvic carboxylase; PCBHomo sapiens (human)
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrialEC 1.2.4.1; PDHE1-A type IHomo sapiens (human)
Mitochondrial 2-oxoglutarate/malate carrier proteinOGCP; Solute carrier family 25 member 11Homo sapiens (human)
Mitochondrial pyruvate carrier 1Brain protein 44-like proteinHomo sapiens (human)
Mitochondrial citrate transport protein Homo sapiens (human)

Compounds (16)

CompoundDescription
hydronium ion
pyruvic acidAn intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
Orthophosphate
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
NADH
GlucoseA primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient replacement.
Adenosine TriphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
hydrogen carbonate
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Coenzyme A
NADA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
oxaloacetic acidA dicarboxylic acid ketone that is an important metabolic intermediate of the CITRIC ACID CYCLE. It can be converted to ASPARTIC ACID by ASPARTATE TRANSAMINASE.
malic acid
acetyl coenzyme aAcetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.
creolinfrom refined coal tar oils