Page last updated: 2024-10-06

Transcriptional regulation of granulopoiesis

Proteins (27)

ProteinSynonymsTaxonomy
Transcriptional activator MybProto-oncogene c-MybHomo sapiens (human)
Runt-related transcription factor 1Acute myeloid leukemia 1 protein; Core-binding factor subunit alpha-2; CBF-alpha-2; Oncogene AML-1; Polyomavirus enhancer-binding protein 2 alpha B subunit; PEA2-alpha B; PEBP2-alpha B; SL3-3 enhancer factor 1 alpha B subunit; SL3/AKV core-binding factor Homo sapiens (human)
Cyclin-dependent kinase 2EC 2.7.11.22; Cell division protein kinase 2; p33 protein kinaseHomo sapiens (human)
Krueppel-like factor 5Basic transcription element-binding protein 2; BTE-binding protein 2; Colon krueppel-like factor; GC-box-binding protein 2; Intestinal-enriched krueppel-like factor; Transcription factor BTEB2Homo sapiens (human)
Granulocyte colony-stimulating factor receptorG-CSF receptor; G-CSF-RHomo sapiens (human)
Cyclin-dependent kinase 4EC 2.7.11.22; Cell division protein kinase 4; PSK-J3Homo sapiens (human)
Retinoic acid receptor RXR-alphaNuclear receptor subfamily 2 group B member 1; Retinoid X receptor alphaHomo sapiens (human)
Signal transducer and activator of transcription 3Acute-phase response factorHomo sapiens (human)
Histone acetyltransferase p300p300 HAT; EC 2.3.1.48; E1A-associated protein p300; Histone butyryltransferase p300; 2.3.1.-; Histone crotonyltransferase p300; 2.3.1.-; Protein 2-hydroxyisobutyryltransferase p300; 2.3.1.-; Protein propionyltransferase p300; 2.3.1.-Homo sapiens (human)
Cyclic AMP-responsive element-binding protein 1CREB-1; cAMP-responsive element-binding protein 1Homo sapiens (human)
Endothelial transcription factor GATA-2GATA-binding protein 2Homo sapiens (human)
Myc proto-oncogene proteinClass E basic helix-loop-helix protein 39; bHLHe39; Proto-oncogene c-Myc; Transcription factor p64Homo sapiens (human)
Retinoic acid receptor alphaRAR-alpha; Nuclear receptor subfamily 1 group B member 1Homo sapiens (human)
Cyclin-dependent kinase inhibitor 1CDK-interacting protein 1; Melanoma differentiation-associated protein 6; MDA-6; p21Homo sapiens (human)
Histone H4Homo sapiens (human)
Transcription factor E2F1E2F-1; PBR3; Retinoblastoma-associated protein 1; RBAP-1; Retinoblastoma-binding protein 3; RBBP-3; pRB-binding protein E2F-1Homo sapiens (human)
Histone-lysine N-methyltransferase 2ALysine N-methyltransferase 2A; EC 2.1.1.354; ALL-1; CXXC-type zinc finger protein 7; Myeloid/lymphoid or mixed-lineage leukemia; Myeloid/lymphoid or mixed-lineage leukemia protein 1; Trithorax-like protein; Zinc finger protein HRXHomo sapiens (human)
Friend leukemia integration 1 transcription factorProto-oncogene Fli-1; Transcription factor ERGBHomo sapiens (human)
Lymphoid enhancer-binding factor 1LEF-1; T cell-specific transcription factor 1-alpha; TCF1-alphaHomo sapiens (human)
CCAAT/enhancer-binding protein betaC/EBP beta; Liver activator protein; LAP; Liver-enriched inhibitory protein; LIP; Nuclear factor NF-IL6; Transcription factor 5; TCF-5Homo sapiens (human)
Interleukin-6 receptor subunit alphaIL-6 receptor subunit alpha; IL-6R subunit alpha; IL-6R-alpha; IL-6RA; IL-6R 1; Membrane glycoprotein 80; gp80Homo sapiens (human)
T-cell acute lymphocytic leukemia protein 1TAL-1; Class A basic helix-loop-helix protein 17; bHLHa17; Stem cell protein; T-cell leukemia/lymphoma protein 5Homo sapiens (human)
CCAAT/enhancer-binding protein alphaC/EBP alphaHomo sapiens (human)
Protein DEKHomo sapiens (human)
Transcription factor PU.131 kDa-transforming proteinHomo sapiens (human)
CCAAT/enhancer-binding protein epsilonC/EBP epsilonHomo sapiens (human)
Zinc finger protein Gfi-1Growth factor independent protein 1; Zinc finger protein 163Homo sapiens (human)

Compounds (1)

CompoundDescription
tretinoinAn important regulator of GENE EXPRESSION during growth and development, and in NEOPLASMS. Tretinoin, also known as retinoic acid and derived from maternal VITAMIN A, is essential for normal GROWTH; and EMBRYONIC DEVELOPMENT. An excess of tretinoin can be teratogenic. It is used in the treatment of PSORIASIS; ACNE VULGARIS; and several other SKIN DISEASES. It has also been approved for use in promyelocytic leukemia (LEUKEMIA, PROMYELOCYTIC, ACUTE).