Page last updated: 2024-10-06

Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors

Proteins (32)

ProteinSynonymsTaxonomy
Glycoprotein hormones alpha chainAnterior pituitary glycoprotein hormones common subunit alpha; Choriogonadotropin alpha chain; Chorionic gonadotrophin subunit alpha; CG-alpha; Follicle-stimulating hormone alpha chain; FSH-alpha; Follitropin alpha chain; Luteinizing hormone alpha chain; Homo sapiens (human)
Small ubiquitin-related modifier 1SUMO-1; GAP-modifying protein 1; GMP1; SMT3 homolog 3; Sentrin; Ubiquitin-homology domain protein PIC1; Ubiquitin-like protein SMT3C; Smt3C; Ubiquitin-like protein UBL1Homo sapiens (human)
Lysine-specific demethylase 5BEC 1.14.11.67; Cancer/testis antigen 31; CT31; Histone demethylase JARID1B; Jumonji/ARID domain-containing protein 1B; PLU-1; Retinoblastoma-binding protein 2 homolog 1; RBP2-H1; [histone H3]-trimethyl-L-lysine(4) demethylase 5BHomo sapiens (human)
Epidermal growth factor receptorEC 2.7.10.1; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1Homo sapiens (human)
Estrogen receptorER; ER-alpha; Estradiol receptor; Nuclear receptor subfamily 3 group A member 1Homo sapiens (human)
Receptor tyrosine-protein kinase erbB-2EC 2.7.10.1; Metastatic lymph node gene 19 protein; MLN 19; Proto-oncogene Neu; Proto-oncogene c-ErbB-2; Tyrosine kinase-type cell surface receptor HER2; p185erbB2Homo sapiens (human)
Mast/stem cell growth factor receptor KitSCFR; EC 2.7.10.1; Piebald trait protein; PBT; Proto-oncogene c-Kit; Tyrosine-protein kinase Kit; p145 c-kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homologHomo sapiens (human)
60 kDa heat shock protein, mitochondrialEC 5.6.1.7; 60 kDa chaperonin; Chaperonin 60; CPN60; Heat shock protein 60; HSP-60; Hsp60; HuCHA60; Mitochondrial matrix protein P1; P60 lymphocyte proteinHomo sapiens (human)
Histone acetyltransferase p300p300 HAT; EC 2.3.1.48; E1A-associated protein p300; Histone butyryltransferase p300; 2.3.1.-; Histone crotonyltransferase p300; 2.3.1.-; Protein 2-hydroxyisobutyryltransferase p300; 2.3.1.-; Protein propionyltransferase p300; 2.3.1.-Homo sapiens (human)
YEATS domain-containing protein 4Glioma-amplified sequence 41; Gas41; NuMA-binding protein 1; NuBI-1; NuBI1Homo sapiens (human)
Vascular endothelial growth factor AVEGF-A; Vascular permeability factor; VPFHomo sapiens (human)
ATPase family AAA domain-containing protein 2EC 3.6.1.-; AAA nuclear coregulator cancer-associated protein; ANCCAHomo sapiens (human)
Protransforming growth factor alphaHomo sapiens (human)
Myc proto-oncogene proteinClass E basic helix-loop-helix protein 39; bHLHe39; Proto-oncogene c-Myc; Transcription factor p64Homo sapiens (human)
NucleophosminNPM; Nucleolar phosphoprotein B23; Nucleolar protein NO38; NumatrinHomo sapiens (human)
Cyclin-dependent kinase inhibitor 1CDK-interacting protein 1; Melanoma differentiation-associated protein 6; MDA-6; p21Homo sapiens (human)
CREB-binding proteinHistone lysine acetyltransferase CREBBP; 2.3.1.48; Protein-lysine acetyltransferase CREBBP; 2.3.1.-Homo sapiens (human)
SUMO-conjugating enzyme UBC9EC 2.3.2.-; RING-type E3 SUMO transferase UBC9; SUMO-protein ligase; Ubiquitin carrier protein 9; Ubiquitin carrier protein I; Ubiquitin-conjugating enzyme E2 I; Ubiquitin-protein ligase I; p18Homo sapiens (human)
WW domain-containing oxidoreductaseEC 1.1.1.-; Fragile site FRA16D oxidoreductase; Short chain dehydrogenase/reductase family 41C member 1Homo sapiens (human)
Transcription factor AP-2 gammaAP2-gamma; Activating enhancer-binding protein 2 gamma; Transcription factor ERF-1Homo sapiens (human)
Pituitary homeobox 2ALL1-responsive protein ARP1; Homeobox protein PITX2; Paired-like homeodomain transcription factor 2; RIEG bicoid-related homeobox transcription factor; SolurshinHomo sapiens (human)
Transcriptional repressor protein YY1Delta transcription factor; INO80 complex subunit S; NF-E1; Yin and yang 1; YY-1Homo sapiens (human)
Protein DEKHomo sapiens (human)
Apolipoprotein EApo-EHomo sapiens (human)
Transcription factor AP-2-alphaAP2-alpha; AP-2 transcription factor; Activating enhancer-binding protein 2-alpha; Activator protein 2; AP-2Homo sapiens (human)
Choriogonadotropin subunit beta 3Choriogonadotropin subunit beta; CG-beta; Chorionic gonadotropin chain betaHomo sapiens (human)
Myb-related protein BB-Myb; Myb-like protein 2Homo sapiens (human)
Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferaseEC 2.1.1.-; Nucleolar protein 1; Nucleolar protein 2 homolog; Proliferating-cell nucleolar antigen p120; Proliferation-associated nucleolar protein p120Homo sapiens (human)
BTB/POZ domain-containing protein KCTD1Potassium channel tetramerization domain-containing protein 1Homo sapiens (human)
Transcription factor AP-2-betaAP2-beta; Activating enhancer-binding protein 2-betaHomo sapiens (human)
BTB/POZ domain-containing protein KCTD15Potassium channel tetramerization domain-containing protein 15Homo sapiens (human)
Cbp/p300-interacting transactivator 2MSG-related protein 1; MRG-1; P35srjHomo sapiens (human)

Compounds (1)

CompoundDescription
tretinoinAn important regulator of GENE EXPRESSION during growth and development, and in NEOPLASMS. Tretinoin, also known as retinoic acid and derived from maternal VITAMIN A, is essential for normal GROWTH; and EMBRYONIC DEVELOPMENT. An excess of tretinoin can be teratogenic. It is used in the treatment of PSORIASIS; ACNE VULGARIS; and several other SKIN DISEASES. It has also been approved for use in promyelocytic leukemia (LEUKEMIA, PROMYELOCYTIC, ACUTE).