Page last updated: 2024-10-06

Transcriptional regulation by RUNX1

Proteins (120)

ProteinSynonymsTaxonomy
Histone-lysine N-methyltransferase 2DLysine N-methyltransferase 2D; EC 2.1.1.354; ALL1-related protein; Myeloid/lymphoid or mixed-lineage leukemia protein 2Homo sapiens (human)
Thrombospondin-1Glycoprotein GHomo sapiens (human)
Interleukin-3IL-3; Hematopoietic growth factor; Mast cell growth factor; MCGF; Multipotential colony-stimulating factor; P-cell-stimulating factorHomo sapiens (human)
Transcriptional activator MybProto-oncogene c-MybHomo sapiens (human)
Polycomb complex protein BMI-1Polycomb group RING finger protein 4; RING finger protein 51Homo sapiens (human)
Runt-related transcription factor 1Acute myeloid leukemia 1 protein; Core-binding factor subunit alpha-2; CBF-alpha-2; Oncogene AML-1; Polyomavirus enhancer-binding protein 2 alpha B subunit; PEA2-alpha B; PEBP2-alpha B; SL3-3 enhancer factor 1 alpha B subunit; SL3/AKV core-binding factor Homo sapiens (human)
Core-binding factor subunit betaCBF-beta; Polyomavirus enhancer-binding protein 2 beta subunit; PEA2-beta; PEBP2-beta; SL3-3 enhancer factor 1 subunit beta; SL3/AKV core-binding factor beta subunitHomo sapiens (human)
Histone-lysine N-methyltransferase SETD1BEC 2.1.1.354; Lysine N-methyltransferase 2G; SET domain-containing protein 1B; hSET1BHomo sapiens (human)
Leukemia inhibitory factor receptorLIF receptor; LIF-RHomo sapiens (human)
Transcriptional coactivator YAP1Yes-associated protein 1; Protein yorkie homolog; Yes-associated protein YAP65 homologHomo sapiens (human)
Tyrosine-protein kinase ABL1EC 2.7.10.2; Abelson murine leukemia viral oncogene homolog 1; Abelson tyrosine-protein kinase 1; Proto-oncogene c-Abl; p150Homo sapiens (human)
Estrogen receptorER; ER-alpha; Estradiol receptor; Nuclear receptor subfamily 3 group A member 1Homo sapiens (human)
Protein kinase C beta typePKC-B; PKC-beta; EC 2.7.11.13Homo sapiens (human)
Integrin alpha-IIbGPalpha IIb; GPIIb; Platelet membrane glycoprotein IIbHomo sapiens (human)
Proto-oncogene tyrosine-protein kinase SrcEC 2.7.10.2; Proto-oncogene c-Src; pp60c-src; p60-SrcHomo sapiens (human)
Galectin-3Gal-3; 35 kDa lectin; Carbohydrate-binding protein 35; CBP 35; Galactose-specific lectin 3; Galactoside-binding protein; GALBP; IgE-binding protein; L-31; Laminin-binding protein; Lectin L-29; Mac-2 antigenHomo sapiens (human)
Proteasome subunit beta type-9EC 3.4.25.1; Low molecular mass protein 2; Macropain chain 7; Multicatalytic endopeptidase complex chain 7; Proteasome chain 7; Proteasome subunit beta-1i; Really interesting new gene 12 proteinHomo sapiens (human)
Cyclin-dependent kinase 7EC 2.7.11.22; EC 2.7.11.23; 39 kDa protein kinase; p39 Mo15; CDK-activating kinase 1; Cell division protein kinase 7; Serine/threonine-protein kinase 1; TFIIH basal transcription factor complex kinase subunitHomo sapiens (human)
Tyrosine-protein kinase BlkEC 2.7.10.2; B lymphocyte kinase; p55-BlkHomo sapiens (human)
Cyclin-HMO15-associated protein; p34; p37Homo sapiens (human)
Protein kinase C theta typeEC 2.7.11.13; nPKC-thetaHomo sapiens (human)
Tyrosine-protein phosphatase non-receptor type 11EC 3.1.3.48; Protein-tyrosine phosphatase 1D; PTP-1D; Protein-tyrosine phosphatase 2C; PTP-2C; SH-PTP2; SHP-2; Shp2; SH-PTP3Homo sapiens (human)
Histone deacetylase 1HD1; EC 3.5.1.98Homo sapiens (human)
Granulocyte-macrophage colony-stimulating factorGM-CSF; Colony-stimulating factor; CSF; Molgramostin; SargramostimHomo sapiens (human)
Transcription factor NF-E2 45 kDa subunitLeucine zipper protein NF-E2; Nuclear factor, erythroid-derived 2 45 kDa subunit; p45 NF-E2Homo sapiens (human)
Axin-1Axis inhibition protein 1; hAxinHomo sapiens (human)
Proteasome subunit beta type-1Macropain subunit C5; Multicatalytic endopeptidase complex subunit C5; Proteasome component C5; Proteasome gamma chainHomo sapiens (human)
Cathepsin KEC 3.4.22.38; Cathepsin O; Cathepsin O2; Cathepsin XHomo sapiens (human)
Cyclin-dependent kinase 6EC 2.7.11.22; Cell division protein kinase 6; Serine/threonine-protein kinase PLSTIREHomo sapiens (human)
Histone acetyltransferase p300p300 HAT; EC 2.3.1.48; E1A-associated protein p300; Histone butyryltransferase p300; 2.3.1.-; Histone crotonyltransferase p300; 2.3.1.-; Protein 2-hydroxyisobutyryltransferase p300; 2.3.1.-; Protein propionyltransferase p300; 2.3.1.-Homo sapiens (human)
Histone acetyltransferase KAT2BEC 2.3.1.48; Histone acetyltransferase PCAF; Histone acetylase PCAF; Lysine acetyltransferase 2B; P300/CBP-associated factor; P/CAF; Spermidine acetyltransferase KAT2B; 2.3.1.57Homo sapiens (human)
Protein arginine N-methyltransferase 6EC 2.1.1.319; Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6; Histone-arginine N-methyltransferase PRMT6Homo sapiens (human)
Homeodomain-interacting protein kinase 2hHIPk2; EC 2.7.11.1Homo sapiens (human)
Proteasome activator complex subunit 311S regulator complex subunit gamma; REG-gamma; Activator of multicatalytic protease subunit 3; Ki nuclear autoantigen; Proteasome activator 28 subunit gamma; PA28g; PA28gammaHomo sapiens (human)
E3 ubiquitin-protein ligase Itchy homologItch; EC 2.3.2.26; Atrophin-1-interacting protein 4; AIP4; HECT-type E3 ubiquitin transferase Itchy homolog; NFE2-associated polypeptide 1; NAPP1Homo sapiens (human)
Proteasome subunit beta type-3Proteasome chain 13; Proteasome component C10-II; Proteasome theta chainHomo sapiens (human)
26S proteasome non-ATPase regulatory subunit 1026S proteasome regulatory subunit p28; Gankyrin; p28(GANK)Homo sapiens (human)
Histone-lysine N-methyltransferase 2CLysine N-methyltransferase 2C; EC 2.1.1.354; Homologous to ALR protein; Myeloid/lymphoid or mixed-lineage leukemia protein 3Homo sapiens (human)
Nuclear factor of activated T-cells, cytoplasmic 2 NF-ATc2; NFATc2; NFAT pre-existing subunit; NF-ATp; T-cell transcription factor NFAT1Homo sapiens (human)
Proteasome subunit beta type-8EC 3.4.25.1; Low molecular mass protein 7; Macropain subunit C13; Multicatalytic endopeptidase complex subunit C13; Proteasome component C13; Proteasome subunit beta-5i; Really interesting new gene 10 proteinHomo sapiens (human)
Proteasome subunit beta type-5EC 3.4.25.1; Macropain epsilon chain; Multicatalytic endopeptidase complex epsilon chain; Proteasome chain 6; Proteasome epsilon chain; Proteasome subunit MB1; Proteasome subunit XHomo sapiens (human)
Proteasome subunit beta type-2Macropain subunit C7-I; Multicatalytic endopeptidase complex subunit C7-I; Proteasome component C7-IHomo sapiens (human)
Histone H4Homo sapiens (human)
Histone-lysine N-methyltransferase 2ALysine N-methyltransferase 2A; EC 2.1.1.354; ALL-1; CXXC-type zinc finger protein 7; Myeloid/lymphoid or mixed-lineage leukemia; Myeloid/lymphoid or mixed-lineage leukemia protein 1; Trithorax-like protein; Zinc finger protein HRXHomo sapiens (human)
Nuclear receptor subfamily 4 group A member 3Mitogen-induced nuclear orphan receptor; Neuron-derived orphan receptor 1; Nuclear hormone receptor NOR-1Homo sapiens (human)
CREB-binding proteinHistone lysine acetyltransferase CREBBP; 2.3.1.48; Protein-lysine acetyltransferase CREBBP; 2.3.1.-Homo sapiens (human)
Protein arginine N-methyltransferase 1EC 2.1.1.319; Histone-arginine N-methyltransferase PRMT1; Interferon receptor 1-bound protein 4Homo sapiens (human)
Interferon gammaIFN-gamma; Immune interferonHomo sapiens (human)
Interleukin-2 receptor subunit alphaIL-2 receptor subunit alpha; IL-2-RA; IL-2R subunit alpha; IL2-RA; TAC antigen; p55Homo sapiens (human)
OccludinHomo sapiens (human)
Proteasome subunit beta type-11EC 3.4.25.1; Proteasome subunit beta-5tHomo sapiens (human)
26S proteasome non-ATPase regulatory subunit 1126S proteasome regulatory subunit RPN6; 26S proteasome regulatory subunit S9; 26S proteasome regulatory subunit p44.5Homo sapiens (human)
26S proteasome non-ATPase regulatory subunit 1226S proteasome regulatory subunit RPN5; 26S proteasome regulatory subunit p55Homo sapiens (human)
26S proteasome non-ATPase regulatory subunit 14EC 3.4.19.-; 26S proteasome regulatory subunit RPN11; 26S proteasome-associated PAD1 homolog 1Homo sapiens (human)
Proteasome subunit alpha type-7Proteasome subunit RC6-1; Proteasome subunit XAPC7Homo sapiens (human)
26S proteasome non-ATPase regulatory subunit 326S proteasome regulatory subunit RPN3; 26S proteasome regulatory subunit S3; Proteasome subunit p58Homo sapiens (human)
26S proteasome regulatory subunit 6A26S proteasome AAA-ATPase subunit RPT5; Proteasome 26S subunit ATPase 3; Proteasome subunit P50; Tat-binding protein 1; TBP-1Homo sapiens (human)
Proteasome subunit alpha type-130 kDa prosomal protein; PROS-30; Macropain subunit C2; Multicatalytic endopeptidase complex subunit C2; Proteasome component C2; Proteasome nu chainHomo sapiens (human)
Proteasome subunit alpha type-2Macropain subunit C3; Multicatalytic endopeptidase complex subunit C3; Proteasome component C3Homo sapiens (human)
Proteasome subunit alpha type-3Macropain subunit C8; Multicatalytic endopeptidase complex subunit C8; Proteasome component C8Homo sapiens (human)
Proteasome subunit alpha type-4Macropain subunit C9; Multicatalytic endopeptidase complex subunit C9; Proteasome component C9; Proteasome subunit LHomo sapiens (human)
Proteasome subunit alpha type-5Macropain zeta chain; Multicatalytic endopeptidase complex zeta chain; Proteasome zeta chainHomo sapiens (human)
Proteasome subunit beta type-426 kDa prosomal protein; HsBPROS26; PROS-26; Macropain beta chain; Multicatalytic endopeptidase complex beta chain; Proteasome beta chain; Proteasome chain 3; HsN3Homo sapiens (human)
Proteasome subunit beta type-6EC 3.4.25.1; Macropain delta chain; Multicatalytic endopeptidase complex delta chain; Proteasome delta chain; Proteasome subunit YHomo sapiens (human)
26S proteasome regulatory subunit 726S proteasome AAA-ATPase subunit RPT1; Proteasome 26S subunit ATPase 2; Protein MSS1Homo sapiens (human)
Proteasome subunit beta type-10EC 3.4.25.1; Low molecular mass protein 10; Macropain subunit MECl-1; Multicatalytic endopeptidase complex subunit MECl-1; Proteasome MECl-1; Proteasome subunit beta-2iHomo sapiens (human)
26S proteasome regulatory subunit 6B26S proteasome AAA-ATPase subunit RPT3; MB67-interacting protein; MIP224; Proteasome 26S subunit ATPase 4; Tat-binding protein 7; TBP-7Homo sapiens (human)
26S proteasome non-ATPase regulatory subunit 826S proteasome regulatory subunit RPN12; 26S proteasome regulatory subunit S14; p31Homo sapiens (human)
26S proteasome non-ATPase regulatory subunit 726S proteasome regulatory subunit RPN8; 26S proteasome regulatory subunit S12; Mov34 protein homolog; Proteasome subunit p40Homo sapiens (human)
CDK-activating kinase assembly factor MAT1CDK7/cyclin-H assembly factor; Cyclin-G1-interacting protein; Menage a trois; RING finger protein 66; RING finger protein MAT1; p35; p36Homo sapiens (human)
26S proteasome non-ATPase regulatory subunit 426S proteasome regulatory subunit RPN10; 26S proteasome regulatory subunit S5A; Antisecretory factor 1; AF; ASF; Multiubiquitin chain-binding proteinHomo sapiens (human)
Interleukin-2IL-2; T-cell growth factor; TCGFHomo sapiens (human)
26S proteasome complex subunit SEM126S proteasome complex subunit DSS1; Deleted in split hand/split foot protein 1; Split hand/foot deleted protein 1; Split hand/foot malformation type 1 proteinHomo sapiens (human)
Proteasome subunit alpha type-627 kDa prosomal protein; PROS-27; p27K; Macropain iota chain; Multicatalytic endopeptidase complex iota chain; Proteasome iota chainHomo sapiens (human)
26S proteasome regulatory subunit 4P26s4; 26S proteasome AAA-ATPase subunit RPT2; Proteasome 26S subunit ATPase 1Homo sapiens (human)
26S proteasome regulatory subunit 826S proteasome AAA-ATPase subunit RPT6; Proteasome 26S subunit ATPase 5; Proteasome subunit p45; Thyroid hormone receptor-interacting protein 1; TRIP1; p45/SUGHomo sapiens (human)
26S proteasome regulatory subunit 10B26S proteasome AAA-ATPase subunit RPT4; Proteasome 26S subunit ATPase 6; Proteasome subunit p42Homo sapiens (human)
26S proteasome non-ATPase regulatory subunit 226S proteasome regulatory subunit RPN1; 26S proteasome regulatory subunit S2; 26S proteasome subunit p97; Protein 55.11; Tumor necrosis factor type 1 receptor-associated protein 2Homo sapiens (human)
26S proteasome non-ATPase regulatory subunit 626S proteasome regulatory subunit RPN7; 26S proteasome regulatory subunit S10; Breast cancer-associated protein SGA-113M; Phosphonoformate immuno-associated protein 4; Proteasome regulatory particle subunit p44S10; p42AHomo sapiens (human)
Proteasome subunit alpha-type 8Proteasome alpha 4 subunit; Alpha4s; Proteasome subunit alpha-type 7-likeHomo sapiens (human)
Proteasome subunit beta type-7EC 3.4.25.1; Macropain chain Z; Multicatalytic endopeptidase complex chain Z; Proteasome subunit ZHomo sapiens (human)
26S proteasome non-ATPase regulatory subunit 126S proteasome regulatory subunit RPN2; 26S proteasome regulatory subunit S1; 26S proteasome subunit p112Homo sapiens (human)
26S proteasome non-ATPase regulatory subunit 1326S proteasome regulatory subunit RPN9; 26S proteasome regulatory subunit S11; 26S proteasome regulatory subunit p40.5Homo sapiens (human)
Proteasome activator complex subunit 111S regulator complex subunit alpha; REG-alpha; Activator of multicatalytic protease subunit 1; Interferon gamma up-regulated I-5111 protein; IGUP I-5111; Proteasome activator 28 subunit alpha; PA28a; PA28alphaHomo sapiens (human)
Glycerol-3-phosphate acyltransferase 1, mitochondrialGPAT-1; EC 2.3.1.15Homo sapiens (human)
Proteasome activator complex subunit 211S regulator complex subunit beta; REG-beta; Activator of multicatalytic protease subunit 2; Proteasome activator 28 subunit beta; PA28b; PA28betaHomo sapiens (human)
Protein PMLPromyelocytic leukemia protein; RING finger protein 71; Tripartite motif-containing protein 19Homo sapiens (human)
Cytotoxic T-lymphocyte protein 4Cytotoxic T-lymphocyte-associated antigen 4; CTLA-4Homo sapiens (human)
Histone-lysine N-methyltransferase SETD1AEC 2.1.1.354; Lysine N-methyltransferase 2F; SET domain-containing protein 1A; hSET1A; Set1/Ash2 histone methyltransferase complex subunit SET1Homo sapiens (human)
Tight junction protein ZO-1Tight junction protein 1; Zona occludens protein 1; Zonula occludens protein 1Homo sapiens (human)
Tumor protein p73p53-like transcription factor; p53-related proteinHomo sapiens (human)
Tumor necrosis factor receptor superfamily member 18Activation-inducible TNFR family receptor; Glucocorticoid-induced TNFR-related proteinHomo sapiens (human)
Claudin-5Transmembrane protein deleted in VCFS; TMDVCFHomo sapiens (human)
Suppressor of cytokine signaling 4SOCS-4; Suppressor of cytokine signaling 7; SOCS-7Homo sapiens (human)
26S proteasome non-ATPase regulatory subunit 926S proteasome regulatory subunit p27Homo sapiens (human)
T-cell acute lymphocytic leukemia protein 1TAL-1; Class A basic helix-loop-helix protein 17; bHLHa17; Stem cell protein; T-cell leukemia/lymphoma protein 5Homo sapiens (human)
LIM domain-binding protein 1LDB-1; Carboxyl-terminal LIM domain-binding protein 2; CLIM-2; LIM domain-binding factor CLIM2; hLdb1; Nuclear LIM interactorHomo sapiens (human)
Forkhead box protein P3ScurfinHomo sapiens (human)
Suppressor of cytokine signaling 3SOCS-3; Cytokine-inducible SH2 protein 3; CIS-3; STAT-induced STAT inhibitor 3; SSI-3Homo sapiens (human)
Platelet glycoprotein Ib alpha chainGP-Ib alpha; GPIb-alpha; GPIbA; Glycoprotein Ibalpha; Antigen CD42b-alphaHomo sapiens (human)
Erythroid transcription factorEryf1; GATA-binding factor 1; GATA-1; GF-1; NF-E1 DNA-binding proteinHomo sapiens (human)
Complement receptor type 1C3b/C4b receptorHomo sapiens (human)
Transcription factor PU.131 kDa-transforming proteinHomo sapiens (human)
Myosin regulatory light polypeptide 920 kDa myosin light chain; LC20; MLC-2C; Myosin RLC; Myosin regulatory light chain 2, smooth muscle isoform; Myosin regulatory light chain 9; Myosin regulatory light chain MRLC1Homo sapiens (human)
ETS-related transcription factor Elf-1E74-like factor 1Homo sapiens (human)
Paired box protein Pax-5B-cell-specific transcription factor; BSAPHomo sapiens (human)
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1BRG1-associated factor 47; BAF47; Integrase interactor 1 protein; SNF5 homolog; hSNF5Homo sapiens (human)
Proteasome activator complex subunit 4Proteasome activator PA200Homo sapiens (human)
ETS-related transcription factor Elf-2E74-like factor 2; New ETS-related factorHomo sapiens (human)
26S proteasome non-ATPase regulatory subunit 526S protease subunit S5 basic; 26S proteasome subunit S5BHomo sapiens (human)
Polycomb group RING finger protein 5RING finger protein 159Homo sapiens (human)
Zinc finger protein ZFPM1Friend of GATA protein 1; FOG-1; Friend of GATA 1; Zinc finger protein 89A; Zinc finger protein multitype 1Homo sapiens (human)
BTB/POZ domain-containing protein KCTD6KCASH3 protein; Potassium channel tetramerization domain-containing protein 6Homo sapiens (human)
SWI/SNF complex subunit SMARCC2BRG1-associated factor 170; BAF170; SWI/SNF complex 170 kDa subunit; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2Homo sapiens (human)
Autism susceptibility gene 2 proteinHomo sapiens (human)
Proteasome inhibitor PI31 subunithPI31Homo sapiens (human)
SWI/SNF complex subunit SMARCC1BRG1-associated factor 155; BAF155; SWI/SNF complex 155 kDa subunit; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1Homo sapiens (human)
R-spondin-3Protein with TSP type-1 repeat; hPWTSR; Roof plate-specific spondin-3; hRspo3; Thrombospondin type-1 domain-containing protein 2Homo sapiens (human)
Helicase MOV-10EC 3.6.4.13; Armitage homolog; Moloney leukemia virus 10 proteinHomo sapiens (human)
Serpin B13HaCaT UV-repressible serpin; Hurpin; Headpin; Peptidase inhibitor 13; PI-13; Proteinase inhibitor 13Homo sapiens (human)

Compounds (5)

CompoundDescription
Orthophosphate
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
s-adenosylmethioninePhysiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed)