| Protein | Synonyms | Taxonomy |
|---|
| NAD-dependent protein lipoamidase sirtuin-4, mitochondrial | EC 2.3.1.-; NAD-dependent ADP-ribosyltransferase sirtuin-4; 2.4.2.-; NAD-dependent protein deacetylase sirtuin-4; 2.3.1.286; Regulatory protein SIR2 homolog 4; SIR2-like protein 4 | Homo sapiens (human) |
| Histone deacetylase 3 | HD3; EC 3.5.1.98; RPD3-2; SMAP45 | Homo sapiens (human) |
| F-box-like/WD repeat-containing protein TBL1XR1 | Nuclear receptor corepressor/HDAC3 complex subunit TBLR1; TBL1-related protein 1; Transducin beta-like 1X-related protein 1 | Homo sapiens (human) |
| Peroxisome proliferator-activated receptor gamma coactivator 1-alpha | PGC-1-alpha; PPAR-gamma coactivator 1-alpha; PPARGC-1-alpha; Ligand effect modulator 6 | Homo sapiens (human) |
| Retinoic acid receptor RXR-alpha | Nuclear receptor subfamily 2 group B member 1; Retinoid X receptor alpha | Homo sapiens (human) |
| Calcium/calmodulin-dependent protein kinase type IV | CaMK IV; EC 2.7.11.17; CaM kinase-GR | Homo sapiens (human) |
| NAD-dependent protein deacetylase sirtuin-3, mitochondrial | hSIRT3; EC 2.3.1.286; Regulatory protein SIR2 homolog 3; SIR2-like protein 3 | Homo sapiens (human) |
| Cyclic AMP-responsive element-binding protein 1 | CREB-1; cAMP-responsive element-binding protein 1 | Homo sapiens (human) |
| Cytochrome c | | Homo sapiens (human) |
| Transcription factor A, mitochondrial | mtTFA; Mitochondrial transcription factor 1; MtTF1; Transcription factor 6; TCF-6; Transcription factor 6-like 2 | Homo sapiens (human) |
| Nuclear receptor corepressor 1 | N-CoR; N-CoR1 | Homo sapiens (human) |
| ATP synthase subunit beta, mitochondrial | EC 7.1.2.2; ATP synthase F1 subunit beta | Homo sapiens (human) |
| Calmodulin-1 | | Homo sapiens (human) |
| Steroid hormone receptor ERR1 | Estrogen receptor-like 1; Estrogen-related receptor alpha; ERR-alpha; Nuclear receptor subfamily 3 group B member 1 | Homo sapiens (human) |
| NAD-dependent protein deacylase sirtuin-5, mitochondrial | EC 2.3.1.-; Regulatory protein SIR2 homolog 5; SIR2-like protein 5 | Homo sapiens (human) |
| DNA-directed RNA polymerase, mitochondrial | MtRPOL; EC 2.7.7.6 | Homo sapiens (human) |
| Cyclic AMP-dependent transcription factor ATF-2 | cAMP-dependent transcription factor ATF-2; Activating transcription factor 2; Cyclic AMP-responsive element-binding protein 2; CREB-2; cAMP-responsive element-binding protein 2; HB16; cAMP response element-binding protein CRE-BP1 | Homo sapiens (human) |
| Host cell factor 1 | HCF; HCF-1; C1 factor; CFF; VCAF; VP16 accessory protein | Homo sapiens (human) |
| DNA polymerase subunit gamma-2, mitochondrial | DNA polymerase gamma accessory 55 kDa subunit; p55; Mitochondrial DNA polymerase accessory subunit; MtPolB; PolG-beta | Homo sapiens (human) |
| Transcription termination factor 1, mitochondrial | Mitochondrial transcription termination factor 1; mTERF; mTERF1 | Homo sapiens (human) |
| Peroxisome proliferator-activated receptor gamma coactivator 1-beta | PGC-1-beta; PPAR-gamma coactivator 1-beta; PPARGC-1-beta; PGC-1-related estrogen receptor alpha coactivator | Homo sapiens (human) |
| Peroxisome proliferator-activated receptor gamma coactivator-related protein 1 | PGC-1-related coactivator; PRC | Homo sapiens (human) |
| Nuclear respiratory factor 1 | NRF-1; Alpha palindromic-binding protein; Alpha-pal | Homo sapiens (human) |
| 5-aminolevulinate synthase, nonspecific, mitochondrial | ALAS-H; EC 2.3.1.37; 5-aminolevulinic acid synthase 1; Delta-ALA synthase 1; Delta-aminolevulinate synthase 1 | Homo sapiens (human) |
| F-box-like/WD repeat-containing protein TBL1X | SMAP55; Transducin beta-like protein 1X; Transducin-beta-like protein 1, X-linked | Homo sapiens (human) |
| Single-stranded DNA-binding protein, mitochondrial | Mt-SSB; MtSSB; PWP1-interacting protein 17 | Homo sapiens (human) |
| GA-binding protein alpha chain | GABP subunit alpha; Nuclear respiratory factor 2 subunit alpha; Transcription factor E4TF1-60 | Homo sapiens (human) |
| PGC-1 and ERR-induced regulator in muscle protein 1 | PPARGC1 and ESRR-induced regulator in muscle 1; Peroxisome proliferator-activated receptor gamma coactivator 1 and estrogen-related receptor-induced regulator in muscle 1 | Homo sapiens (human) |
| Dimethyladenosine transferase 1, mitochondrial | EC 2.1.1.-; Mitochondrial 12S rRNA dimethylase 1; Mitochondrial transcription factor B1; h-mtTFB; h-mtTFB1; hTFB1M; mtTFB1; S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 1 | Homo sapiens (human) |
| Twinkle protein, mitochondrial | EC 3.6.4.12; Progressive external ophthalmoplegia 1 protein; T7 gp4-like protein with intramitochondrial nucleoid localization; T7-like mitochondrial DNA helicase; Twinkle mtDNA helicase | Homo sapiens (human) |
| Dimethyladenosine transferase 2, mitochondrial | EC 2.1.1.-; Hepatitis C virus NS5A-transactivated protein 5; HCV NS5A-transactivated protein 5; Mitochondrial 12S rRNA dimethylase 2; Mitochondrial transcription factor B2; h-mtTFB; h-mtTFB2; hTFB2M; mtTFB2; S-adenosylmethionine-6-N', N'-adenosyl(rRNA) di | Homo sapiens (human) |
| Compound | Description |
|---|
| Calcium | A basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes. |
| Zinc | A metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn. |
| adenosine diphosphate | Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position. |
| niacinamide | An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and PELLAGRA. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake. |
| o-acetyl-adp-ribose | An acetyl ester of ADENOSINE DIPHOSPHATE RIBOSE formed during NAD-dependent deacetylation of proteins by SIRTUINS. The acetate group resides on the ribose ring where nicotinamide was cleaved from NAD during the reaction. Several isomers of O-acetyl-ADP-ribose have been isolated from the reaction. |
| nad | A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed) |
| adenosine triphosphate | An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter. |