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Trans-sulfuration and one-carbon metabolism

Proteins (0)

Compounds (17)

CompoundDescription
GlutathioneA tripeptide with many roles in cells. It conjugates to drugs to make them more soluble for excretion, is a cofactor for some enzymes, is involved in protein disulfide bond rearrangement and reduces peroxides.
5-methyltetrahydrofolate
s-adenosylmethioninePhysiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed)
cysteineA thiol-containing non-essential amino acid that is oxidized to form CYSTINE.
methionineA sulfur-containing essential L-amino acid that is important in many body functions.
glycineA non-essential amino acid. It is found primarily in gelatin and silk fibroin and used therapeutically as a nutrient. It is also a fast inhibitory neurotransmitter.
dihydrofolateRN given refers to (L)-isomer
5,6,7,8-tetrahydrofolic acidRN given refers to (DL)-isomer
phosphohydroxypyruvic acid
CystathionineSulfur-containing amino acid formed as an intermediate in the conversion of METHIONINE to CYSTEINE.
serineA non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
3-phosphoglycerate
thymidine monophosphate5-Thymidylic acid. A thymine nucleotide containing one phosphate group esterified to the deoxyribose moiety.
s-adenosylhomocysteine5'-S-(3-Amino-3-carboxypropyl)-5'-thioadenosine. Formed from S-adenosylmethionine after transmethylation reactions.
2'-deoxyuridylic acidRN given refers to parent cpd
plasmenylserineRN given refers to (L)-isomer
homocysteineA thiol-containing amino acid formed by a demethylation of METHIONINE.