Page last updated: 2024-10-06

Threonine Biosynthesis

Proteins (11)

ProteinSynonymsTaxonomy
Bifunctional aspartokinase/homoserine dehydrogenase 1Aspartokinase I/homoserine dehydrogenase I; AKI-HDIEscherichia coli K-12
Homoserine kinaseHK; HSK; EC 2.7.1.39Escherichia coli K-12
Aspartate aminotransferaseAspAT; EC 2.6.1.1; Transaminase AEscherichia coli K-12
Lysine-sensitive aspartokinase 3EC 2.7.2.4; Aspartate kinase III; AKIII; Lysine-sensitive aspartokinase IIIEscherichia coli K-12
L-threonine 3-dehydrogenaseTDH; EC 1.1.1.103; L-threonine dehydrogenaseEscherichia coli K-12
Threonine synthaseTS; EC 4.2.3.1Escherichia coli K-12
2-amino-3-ketobutyrate coenzyme A ligaseAKB ligase; EC 2.3.1.29; Glycine acetyltransferaseEscherichia coli K-12
Bifunctional aspartokinase/homoserine dehydrogenase 2Aspartokinase II/homoserine dehydrogenase II; AKII-HDIIEscherichia coli K-12
Aspartate-semialdehyde dehydrogenaseASA dehydrogenase; ASADH; EC 1.2.1.11; Aspartate-beta-semialdehyde dehydrogenaseEscherichia coli K-12
Stress response kinase AEC 2.7.11.1; Serine/threonine protein kinase YihE; Serine/threonine-protein kinase SrkAEscherichia coli K-12
Threonine/serine transporter TdcCH(+)/threonine-serine symporterEscherichia coli str. K-12 substr. DH10B

Compounds (19)

CompoundDescription
hydronium ion
Orthophosphate
glutamic acidA non-essential amino acid naturally occurring in the L-form. Glutamic acid is the most common excitatory neurotransmitter in the CENTRAL NERVOUS SYSTEM.
NADH
Adenosine TriphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
threonineAn essential amino acid occurring naturally in the L-form, which is the active form. It is found in eggs, milk, gelatin, and other proteins.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Coenzyme A
aminomalonic acidaspartase-ammonia ligase inhibitor
homoserine
o-phosphohomoserineRN given refers to L-isomer
aspartic semialdehydeRN given refers to cpd without isomeric designation
2-amino-3-ketobutyrateunstable intermediate in threonine dehydrogenase-initiated pathway for threonine utilization; structure given in first source
alpha-ketoglutaric acid
NADA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
oxaloacetic acidA dicarboxylic acid ketone that is an important metabolic intermediate of the CITRIC ACID CYCLE. It can be converted to ASPARTIC ACID by ASPARTATE TRANSAMINASE.
acetyl coenzyme aAcetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.
creolinfrom refined coal tar oils