Page last updated: 2024-10-06

Tetrahydrofolate Biosynthesis

Proteins (8)

ProteinSynonymsTaxonomy
Aminodeoxychorismate synthaseADC synthase; EC 2.6.1.85; P-aminobenzoic acid synthase; PABA synthase; Para-aminobenzoate synthaseSaccharomyces cerevisiae S288C
Dihydrofolate reductaseEC 1.5.1.3Saccharomyces cerevisiae S288C
Phosphoribosylglycinamide formyltransferaseEC 2.1.2.2; 5'-phosphoribosylglycinamide transformylase; GAR transformylase; GARTSaccharomyces cerevisiae S288C
GTP cyclohydrolase 1EC 3.5.4.16; GTP cyclohydrolase I; GTP-CH-ISaccharomyces cerevisiae S288C
Dihydrofolate synthetaseDHFS; EC 6.3.2.12Saccharomyces cerevisiae S288C
Aminodeoxychorismate lyaseEC 4.1.3.38; 4-amino-4-deoxychorismate lyase; ADC lyase; ADCLSaccharomyces cerevisiae S288C
C-1-tetrahydrofolate synthase, mitochondrialC1-THF synthaseSaccharomyces cerevisiae S288C
Folic acid synthesis protein FOL1Saccharomyces cerevisiae S288C

Compounds (15)

CompoundDescription
hydronium ion
pyruvic acidAn intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
Orthophosphate
glutamic acidA non-essential amino acid naturally occurring in the L-form. Glutamic acid is the most common excitatory neurotransmitter in the CENTRAL NERVOUS SYSTEM.
Adenosine TriphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
glutamineA non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes. It is synthesized from GLUTAMIC ACID and AMMONIA. It is the principal carrier of NITROGEN in the body and is an important energy source for many cells.
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
adenosine monophosphateAdenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
6-hydroxymethyl-7,8-dihydropterin
phosphoribosyl-N-formylglycineamide
chorismic acidA cyclohexadiene carboxylic acid derived from SHIKIMIC ACID and a precursor for the biosynthesis of UBIQUINONE and the AROMATIC AMINO ACIDS.
glycolaldehydestructure
creolinfrom refined coal tar oils
pyrophosphate