Page last updated: 2024-10-06
Terpenoid Backbone Biosynthesis
Proteins (13)
| Protein | Synonyms | Taxonomy |
|---|---|---|
| Dehydrodolichyl diphosphate synthase complex subunit RER2 | DEDOL-PP synthase; EC 2.5.1.87; Ditrans,polycis-polyprenyl diphosphate synthase ((2E,6E)-farnesyl diphosphate specific) | Saccharomyces cerevisiae S288C |
| Dehydrodolichyl diphosphate synthase complex subunit SRT1 | EC 2.5.1.87; Ditrans,polycis-polyprenyl diphosphate synthase ((2E,6E)-farnesyl diphosphate specific) | Saccharomyces cerevisiae S288C |
| Dehydrodolichyl diphosphate synthase complex subunit NUS1 | EC 2.5.1.87; Nuclear undecaprenyl pyrophosphate synthase 1 | Saccharomyces cerevisiae S288C |
| Hydroxymethylglutaryl-CoA synthase | HMG-CoA synthase; EC 2.3.3.10; 3-hydroxy-3-methylglutaryl coenzyme A synthase | Saccharomyces cerevisiae S288C |
| Farnesyl pyrophosphate synthase | FPP synthase; FPS; EC 2.5.1.10; (2E,6E)-farnesyl diphosphate synthase; Dimethylallyltranstransferase; 2.5.1.1; Farnesyl diphosphate synthase; Geranyltranstransferase | Saccharomyces cerevisiae S288C |
| Mevalonate kinase | MK; MvK; EC 2.7.1.36; Ergosterol biosynthesis protein 12; Regulation of autonomous replication protein 1 | Saccharomyces cerevisiae S288C |
| Isopentenyl-diphosphate Delta-isomerase | EC 5.3.3.2; Isopentenyl pyrophosphate isomerase; IPP isomerase | Saccharomyces cerevisiae S288C |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1 | HMG-CoA reductase 1; EC 1.1.1.34 | Saccharomyces cerevisiae S288C |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase 2 | HMG-CoA reductase 2; EC 1.1.1.34 | Saccharomyces cerevisiae S288C |
| Hexaprenyl pyrophosphate synthase, mitochondrial | HPS; EC 2.5.1.- | Saccharomyces cerevisiae S288C |
| Phosphomevalonate kinase | EC 2.7.4.2 | Saccharomyces cerevisiae S288C |
| 3-ketoacyl-CoA thiolase, peroxisomal | EC 2.3.1.16; Acetyl-CoA acyltransferase; Beta-ketothiolase; Peroxisomal 3-oxoacyl-CoA thiolase | Saccharomyces cerevisiae S288C |
| Diphosphomevalonate decarboxylase | EC 4.1.1.33; Ergosterol biosynthesis protein 19; Mevalonate pyrophosphate decarboxylase; Mevalonate-5-diphosphate decarboxylase; MDD; MDDase | Saccharomyces cerevisiae S288C |
Compounds (17)
| Compound | Description |
|---|---|
| Orthophosphate | |
| Carbon Dioxide | A colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals. |
| Adenosine Triphosphate | An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter. |
| adenosine diphosphate | Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position. |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| Coenzyme A | |
| isopentenyl pyrophosphate | substrate for isopentenyl pyrophosphate isomerase; RN given refers to unlabeled cpd; a nonpeptide mycobacterial antigen that stimulates gamma delta T cells |
| 5-diphosphomevalonic acid | RN given refers to ion(1-) |
| farnesyl pyrophosphate | a sesquiterpene that dimerizes to SQUALENE; RN given refers to cpd without isomeric designation |
| geranyl pyrophosphate | RN given refers to (E)-isomer |
| Mevalonic Acid | A dihydroxy monocarboxylic acid and precursor in the biosynthetic pathway known as the mevalonate pathway, which produces terpenes and steroids that are vital for diverse cellular functions. |
| phosphomevalonate | |
| acetyl coenzyme a | Acetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent. |
| geranylgeranyl pyrophosphate | RN given refers to (E,E,E)-isomer |
| creolin | from refined coal tar oils |
| pyrophosphate | |
| 3,3-dimethylallyl pyrophosphate | isomeric with isopentenyl pyrophosphate |