Page last updated: 2024-10-06

TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain

Proteins (11)

ProteinSynonymsTaxonomy
Rab proteins geranylgeranyltransferase component A 1Choroideremia protein; Rab escort protein 1; REP-1; TCD proteinHomo sapiens (human)
Cellular tumor antigen p53Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53Homo sapiens (human)
B-cell lymphoma 6 proteinBCL-6; B-cell lymphoma 5 protein; BCL-5; Protein LAZ-3; Zinc finger and BTB domain-containing protein 27; Zinc finger protein 51Homo sapiens (human)
Geranylgeranyl transferase type-2 subunit alphaEC 2.5.1.60; Geranylgeranyl transferase type II subunit alpha; Rab geranyl-geranyltransferase subunit alpha; Rab GG transferase alpha; Rab GGTase alpha; Rab geranylgeranyltransferase subunit alphaHomo sapiens (human)
Geranylgeranyl transferase type-2 subunit betaEC 2.5.1.60; Geranylgeranyl transferase type II subunit beta; GGTase-II-beta; Rab geranyl-geranyltransferase subunit beta; Rab GG transferase beta; Rab GGTase beta; Rab geranylgeranyltransferase subunit beta; Type II protein geranyl-geranyltransferase subHomo sapiens (human)
Baculoviral IAP repeat-containing protein 5Apoptosis inhibitor 4; Apoptosis inhibitor survivinHomo sapiens (human)
Tumor protein 63p63; Chronic ulcerative stomatitis protein; CUSP; Keratinocyte transcription factor KET; Transformation-related protein 63; TP63; Tumor protein p73-like; p73L; p40; p51Homo sapiens (human)
Protein NDRG1Differentiation-related gene 1 protein; DRG-1; N-myc downstream-regulated gene 1 protein; Nickel-specific induction protein Cap43; Reducing agents and tunicamycin-responsive protein; RTP; Rit42Homo sapiens (human)
Apoptosis facilitator Bcl-2-like protein 14Bcl2-L-14; Apoptosis regulator Bcl-GHomo sapiens (human)
Quinone oxidoreductase PIG3EC 1.-.-.-; Tumor protein p53-inducible protein 3; p53-induced gene 3 proteinHomo sapiens (human)
p53 apoptosis effector related to PMP-22Keratinocyte-associated protein 1; KCP-1; P53-induced protein PIGPC1; Transmembrane protein THWHomo sapiens (human)

Compounds (6)

CompoundDescription
hydronium ion
SuperoxidesHighly reactive compounds produced when oxygen is reduced by a single electron. In biological systems, they may be generated during the normal catalytic function of a number of enzymes and during the oxidation of hemoglobin to METHEMOGLOBIN. In living organisms, SUPEROXIDE DISMUTASE protects the cell from the deleterious effects of superoxides.
OxygenAn element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
1,2-naphthoquinone
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)