Pathways > TP53 Regulates Transcription of Cell Death Genes
Page last updated: 2024-10-06

TP53 Regulates Transcription of Cell Death Genes

Proteins (36)

ProteinSynonymsTaxonomy
Rab proteins geranylgeranyltransferase component A 1Choroideremia protein; Rab escort protein 1; REP-1; TCD proteinHomo sapiens (human)
Phorbol-12-myristate-13-acetate-induced protein 1PMA-induced protein 1; Immediate-early-response protein APR; Protein NoxaHomo sapiens (human)
NLR family CARD domain-containing protein 4CARD, LRR, and NACHT-containing protein; Clan protein; Caspase recruitment domain-containing protein 12; Ice protease-activating factor; IpafHomo sapiens (human)
Cellular tumor antigen p53Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53Homo sapiens (human)
Caspase-1CASP-1; EC 3.4.22.36; Interleukin-1 beta convertase; IL-1BC; Interleukin-1 beta-converting enzyme; ICE; IL-1 beta-converting enzyme; p45Homo sapiens (human)
Caspase-2CASP-2; EC 3.4.22.55; Neural precursor cell expressed developmentally down-regulated protein 2; NEDD-2; Protease ICH-1Homo sapiens (human)
Caspase-6CASP-6; EC 3.4.22.59; Apoptotic protease Mch-2Homo sapiens (human)
BH3-interacting domain death agonistp22 BID; BIDHomo sapiens (human)
Apoptosis regulator BAX Bcl-2-like protein 4; Bcl2-L-4Homo sapiens (human)
B-cell lymphoma 6 proteinBCL-6; B-cell lymphoma 5 protein; BCL-5; Protein LAZ-3; Zinc finger and BTB domain-containing protein 27; Zinc finger protein 51Homo sapiens (human)
Insulin-like growth factor-binding protein 3IBP-3; IGF-binding protein 3; IGFBP-3Homo sapiens (human)
Geranylgeranyl transferase type-2 subunit alphaEC 2.5.1.60; Geranylgeranyl transferase type II subunit alpha; Rab geranyl-geranyltransferase subunit alpha; Rab GG transferase alpha; Rab GGTase alpha; Rab geranylgeranyltransferase subunit alphaHomo sapiens (human)
Bcl-2-binding component 3, isoforms 1/2JFY-1; p53 up-regulated modulator of apoptosisHomo sapiens (human)
Tumor necrosis factor receptor superfamily member 6Apo-1 antigen; Apoptosis-mediating surface antigen FAS; FASLG receptorHomo sapiens (human)
Geranylgeranyl transferase type-2 subunit betaEC 2.5.1.60; Geranylgeranyl transferase type II subunit beta; GGTase-II-beta; Rab geranyl-geranyltransferase subunit beta; Rab GG transferase beta; Rab GGTase beta; Rab geranylgeranyltransferase subunit beta; Type II protein geranyl-geranyltransferase subHomo sapiens (human)
Apoptotic protease-activating factor 1APAF-1Homo sapiens (human)
Baculoviral IAP repeat-containing protein 5Apoptosis inhibitor 4; Apoptosis inhibitor survivinHomo sapiens (human)
Serine-protein kinase ATMEC 2.7.11.1; Ataxia telangiectasia mutated; A-T mutatedHomo sapiens (human)
CREB-binding proteinHistone lysine acetyltransferase CREBBP; 2.3.1.48; Protein-lysine acetyltransferase CREBBP; 2.3.1.-Homo sapiens (human)
Caspase-10CASP-10; EC 3.4.22.63; Apoptotic protease Mch-4; FAS-associated death domain protein interleukin-1B-converting enzyme 2; FLICE2; ICE-like apoptotic protease 4Homo sapiens (human)
Tumor protein 63p63; Chronic ulcerative stomatitis protein; CUSP; Keratinocyte transcription factor KET; Transformation-related protein 63; TP63; Tumor protein p73-like; p73L; p40; p51Homo sapiens (human)
Ferroptosis suppressor protein 1FSP1; EC 1.6.5.-; Apoptosis-inducing factor homologous mitochondrion-associated inducer of death; AMID; p53-responsive gene 3 proteinHomo sapiens (human)
Tumor protein p53-inducible nuclear protein 1Stress-induced protein; p53-dependent damage-inducible nuclear protein 1; p53DINP1Homo sapiens (human)
Protein NDRG1Differentiation-related gene 1 protein; DRG-1; N-myc downstream-regulated gene 1 protein; Nickel-specific induction protein Cap43; Reducing agents and tunicamycin-responsive protein; RTP; Rit42Homo sapiens (human)
Tumor protein p73p53-like transcription factor; p53-related proteinHomo sapiens (human)
p53-induced death domain-containing protein 1EC 3.4.21.-; Leucine-rich repeat and death domain-containing proteinHomo sapiens (human)
Apoptosis facilitator Bcl-2-like protein 14Bcl2-L-14; Apoptosis regulator Bcl-GHomo sapiens (human)
TP53-regulated inhibitor of apoptosis 1Protein 15E1.1; WF-1; p53-inducible cell-survival factor; p53CSVHomo sapiens (human)
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-likeAdenovirus E1B19K-binding protein B5; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A; NIP3-like protein X; NIP3LHomo sapiens (human)
Death domain-containing protein CRADDCaspase and RIP adapter with death domain; RIP-associated protein with a death domainHomo sapiens (human)
Quinone oxidoreductase PIG3EC 1.-.-.-; Tumor protein p53-inducible protein 3; p53-induced gene 3 proteinHomo sapiens (human)
Metalloreductase STEAP3EC 1.16.1.-; Dudulin-2; Six-transmembrane epithelial antigen of prostate 3; Tumor suppressor-activated pathway protein 6; hTSAP6; pHyde; hpHydeHomo sapiens (human)
Insulin-like growth factor-binding protein 3 receptorIGFBP-3R; Transmembrane protein 219Homo sapiens (human)
Zinc finger protein 420Homo sapiens (human)
p53 apoptosis effector related to PMP-22Keratinocyte-associated protein 1; KCP-1; P53-induced protein PIGPC1; Transmembrane protein THWHomo sapiens (human)
p53-regulated apoptosis-inducing protein 1p53AIP1Homo sapiens (human)

Compounds (8)

CompoundDescription
hydronium ion
SuperoxidesHighly reactive compounds produced when oxygen is reduced by a single electron. In biological systems, they may be generated during the normal catalytic function of a number of enzymes and during the oxidation of hemoglobin to METHEMOGLOBIN. In living organisms, SUPEROXIDE DISMUTASE protects the cell from the deleterious effects of superoxides.
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
OxygenAn element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
1,2-naphthoquinone
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.