Page last updated: 2024-10-06

TNFR1 signaling pathway ( TNFR1 signaling pathway )

Proteins (25)

ProteinSynonymsTaxonomy
Inhibitor of nuclear factor kappa-B kinase subunit alphaI-kappa-B kinase alpha; IKK-A; IKK-alpha; IkBKA; IkappaB kinase; EC 2.7.11.10; Conserved helix-loop-helix ubiquitous kinase; I-kappa-B kinase 1; IKK1; Nuclear factor NF-kappa-B inhibitor kinase alpha; NFKBIKA; Transcription factor 16; TCF-16Homo sapiens (human)
Transcription factor p65 Nuclear factor NF-kappa-B p65 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3Mus musculus (house mouse)
Mitogen-activated protein kinase 8MAP kinase 8; MAPK 8; EC 2.7.11.24; SAPK gamma; Stress-activated protein kinase JNK1; c-Jun N-terminal kinase 1; p54 gammaRattus norvegicus (Norway rat)
Caspase-9CASP-9; EC 3.4.22.62; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; APAF-3; ICE-like apoptotic protease 6; ICE-LAP6Homo sapiens (human)
BH3-interacting domain death agonistp22 BID; BIDHomo sapiens (human)
Apoptosis regulator BAX Bcl-2-like protein 4; Bcl2-L-4Homo sapiens (human)
E3 ubiquitin-protein ligase Itchy homologItch; EC 2.3.2.26; Atrophin-1-interacting protein 4; AIP4; HECT-type E3 ubiquitin transferase Itchy homolog; NFE2-associated polypeptide 1; NAPP1Homo sapiens (human)
Caspase-3 CASP-3; EC 3.4.22.56; Apopain; Cysteine protease CPP32; CPP-32; IRP; LICE; Protein Yama; SREBP cleavage activity 1; SCA-1Rattus norvegicus (Norway rat)
Mitogen-activated protein kinase kinase kinase 5EC 2.7.11.25; Apoptosis signal-regulating kinase 1; ASK-1; MAPK/ERK kinase kinase 5; MEK kinase 5; MEKK 5Mus musculus (house mouse)
Dual specificity mitogen-activated protein kinase kinase 7 MAP kinase kinase 7; MAPKK 7; EC 2.7.12.2; JNK-activating kinase 2; MAPK/ERK kinase 7; MEK 7; c-Jun N-terminal kinase kinase 2; JNK kinase 2; JNKK 2Mus musculus (house mouse)
Inhibitor of nuclear factor kappa-B kinase subunit betaI-kappa-B-kinase beta; IKK-B; IKK-beta; IkBKB; EC 2.7.11.10; I-kappa-B kinase 2; IKK2; Nuclear factor NF-kappa-B inhibitor kinase beta; NFKBIKB; Serine/threonine protein kinase IKBKB; 2.7.11.1Rattus norvegicus (Norway rat)
Transcription factor AP-1Activator protein 1; AP1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homologRattus norvegicus (Norway rat)
Fas-associated death domain proteinDeath domain-containing adapter protein BG4; FAS-associating death domain-containing protein; dFADDDrosophila melanogaster (fruit fly)
Nuclear factor NF-kappa-B p105 subunit DNA-binding factor KBF1; EBP-1; NF-kappa-B1 p84/NF-kappa-B1 p98; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1Mus musculus (house mouse)
Apoptotic protease-activating factor 1APAF-1Rattus norvegicus (Norway rat)
CASP8 and FADD-like apoptosis regulator Caspase homolog; CASH; Caspase-eight-related protein; Casper; Caspase-like apoptosis regulatory protein; CLARP; Cellular FLICE-like inhibitory protein; c-FLIP; FADD-like antiapoptotic molecule 1; FLAME-1; Inhibitor of FLICE; I-FLICE; MACH-related inducer Mus musculus (house mouse)
Tumor necrosis factor Cachectin; TNF-alpha; Tumor necrosis factor ligand superfamily member 2; TNF-aRattus norvegicus (Norway rat)
Tumor necrosis factor receptor superfamily member 1A Tumor necrosis factor receptor 1; TNF-R1; Tumor necrosis factor receptor type I; TNF-RI; TNFR-I; p55; p60Rattus norvegicus (Norway rat)
TNF receptor-associated factor 2 EC 2.3.2.27; E3 ubiquitin-protein ligase TRAF2; RING-type E3 ubiquitin transferase TRAF2Mus musculus (house mouse)
Cytochrome c, somaticRattus norvegicus (Norway rat)
Tumor necrosis factor receptor type 1-associated DEATH domain proteinTNFR1-associated DEATH domain protein; TNFRSF1A-associated via death domainHomo sapiens (human)
NF-kappa-B inhibitor alpha I-kappa-B-alpha; IkB-alpha; IkappaBalpha; RL/IF-1Rattus norvegicus (Norway rat)
Caspase-8EC 3.4.22.61; Death-related ced-3/NEDD2-like proteinDrosophila melanogaster (fruit fly)
NF-kappa-B essential modulatorInhibitor of nuclear factor kappa B kinase subunit gamma; DmIKKgamma; NEMO homologDrosophila melanogaster (fruit fly)
Receptor-interacting serine/threonine-protein kinase 3 EC 2.7.11.1; Homocysteine respondent protein HCYP2; RIP-like protein kinase 3; Receptor-interacting protein 3; RIP-3Rattus norvegicus (Norway rat)

Compounds (0)

CompoundDescription