Page last updated: 2024-10-06

TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)

Proteins (12)

ProteinSynonymsTaxonomy
E3 ubiquitin-protein ligase SMURF1hSMURF1; EC 2.3.2.26; HECT-type E3 ubiquitin transferase SMURF1; SMAD ubiquitination regulatory factor 1; SMAD-specific E3 ubiquitin-protein ligase 1Homo sapiens (human)
Protein kinase C zeta typeEC 2.7.11.13; nPKC-zetaHomo sapiens (human)
TGF-beta receptor type-1TGFR-1; EC 2.7.11.30; Activin A receptor type II-like protein kinase of 53kD; Activin receptor-like kinase 5; ALK-5; ALK5; Serine/threonine-protein kinase receptor R4; SKR4; TGF-beta type I receptor; Transforming growth factor-beta receptor type I; TGF-beHomo sapiens (human)
TGF-beta receptor type-2TGFR-2; EC 2.7.11.30; TGF-beta type II receptor; Transforming growth factor-beta receptor type II; TGF-beta receptor type II; TbetaR-IIHomo sapiens (human)
Transforming protein RhoAEC 3.6.5.2; Rho cDNA clone 12; h12Homo sapiens (human)
Peptidyl-prolyl cis-trans isomerase FKBP1APPIase FKBP1A; EC 5.2.1.8; 12 kDa FK506-binding protein; 12 kDa FKBP; FKBP-12; Calstabin-1; FK506-binding protein 1A; FKBP-1A; Immunophilin FKBP12; RotamaseHomo sapiens (human)
Partitioning defective 6 homolog alphaPAR-6; PAR-6 alpha; PAR-6A; PAR6C; Tax interaction protein 40; TIP-40Homo sapiens (human)
Junctional adhesion molecule AJAM-A; Junctional adhesion molecule 1; JAM-1; Platelet F11 receptor; Platelet adhesion molecule 1; PAM-1Homo sapiens (human)
Transforming growth factor beta-1 proproteinHomo sapiens (human)
Partitioning defective 3 homologPAR-3; PARD-3; Atypical PKC isotype-specific-interacting protein; ASIP; CTCL tumor antigen se2-5; PAR3-alphaHomo sapiens (human)
Rho guanine nucleotide exchange factor 18114 kDa Rho-specific guanine nucleotide exchange factor; p114-Rho-GEF; p114RhoGEF; Septin-associated RhoGEF; SA-RhoGEFHomo sapiens (human)
CingulinHomo sapiens (human)

Compounds (3)

CompoundDescription
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
Guanosine MonophosphateA guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature.
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.