Page last updated: 2024-10-06

TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)

Proteins (12)

ProteinSynonymsTaxonomy
Isocitrate lyaseICL; EC 4.1.3.1; Isocitrase; IsocitrataseMycobacterium tuberculosis H37Rv
Aconitate hydratase AACN; Aconitase; EC 4.2.1.3; (2R,3S)-2-methylisocitrate dehydratase; (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate dehydratase; Iron-responsive protein-like; IRP-like; Probable 2-methyl-cis-aconitate hydratase; 4.2.1.99; RNA-binding proteinMycobacterium tuberculosis H37Rv
2-oxoglutarate oxidoreductase subunit KorBEC 1.2.7.3; Alpha-ketoglutarate oxidoreductase subunit beta; KG oxidoreductase subunit beta; KGO subunit beta; KOR subunit betaMycobacterium tuberculosis H37Rv
2-oxoglutarate oxidoreductase subunit KorAEC 1.2.7.3; Alpha-ketoglutarate oxidoreductase subunit alpha/gamma; KG oxidoreductase subunit alpha/gamma; KGO subunit alpha/gamma; KOR subunit alpha/gammaMycobacterium tuberculosis H37Rv
Fumarate hydratase class IIFumarase C; EC 4.2.1.2; Aerobic fumarase; Iron-independent fumaraseMycobacterium tuberculosis H37Rv
Malate dehydrogenaseEC 1.1.1.37Mycobacterium tuberculosis H37Rv
Succinate--CoA ligase [ADP-forming] subunit betaEC 6.2.1.5; Succinyl-CoA synthetase subunit beta; SCS-betaMycobacterium tuberculosis H37Rv
Succinate--CoA ligase [ADP-forming] subunit alphaEC 6.2.1.5; Succinyl-CoA synthetase subunit alpha; SCS-alphaMycobacterium tuberculosis H37Rv
Malate synthase GEC 2.3.3.9Mycobacterium tuberculosis H37Rv
Isocitrate dehydrogenase [NADP]IDH; EC 1.1.1.42; IDP; NADP(+)-specific ICDH; Oxalosuccinate decarboxylaseMycobacterium tuberculosis H37Rv
Citrate synthase 1EC 2.3.3.16Mycobacterium tuberculosis H37Rv
Succinate dehydrogenase flavoprotein subunit Mycobacterium tuberculosis H37Rv

Compounds (27)

CompoundDescription
hydronium ion
Thiamine PyrophosphateThe coenzyme form of Vitamin B1 present in many animal tissues. It is a required intermediate in the PYRUVATE DEHYDROGENASE COMPLEX and the KETOGLUTARATE DEHYDROGENASE COMPLEX.
Succinate
NADH
ManganeseA trace element with atomic symbol Mn, atomic number 25, and atomic weight 54.94. It is concentrated in cell mitochondria, mostly in the pituitary gland, liver, pancreas, kidney, and bone, influences the synthesis of mucopolysaccharides, stimulates hepatic synthesis of cholesterol and fatty acids, and is a cofactor in many enzymes, including arginase and alkaline phosphatase in the liver. (From AMA Drug Evaluations Annual 1992, p2035)
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
serum p-componentclose relation to C reactive protein; may be ovosomucoid
ZincA metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn.
Orthophosphate
fumaratesCompounds based on fumaric acid.
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
MagnesiumA metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
succinyl-coenzyme A
nadA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
alpha-Ketoglutarate
OxaloacetateAn anionic form of oxaloacetic acid.
glyoxylate
itaconate
glutamate
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
3-nitropropionate
bromopyruvate
Coenzyme A
Acetyl Coenzyme AAcetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.