Page last updated: 2024-10-06

Synthesis of Ketone Bodies

Proteins (8)

ProteinSynonymsTaxonomy
3-hydroxybutyrate dehydrogenase type 2EC 1.1.1.-; EC 1.1.1.30; Dehydrogenase/reductase SDR family member 6; Oxidoreductase UCPA; R-beta-hydroxybutyrate dehydrogenase; Short chain dehydrogenase/reductase family 15C member 1Homo sapiens (human)
Hydroxymethylglutaryl-CoA synthase, mitochondrialHMG-CoA synthase; EC 2.3.3.10; 3-hydroxy-3-methylglutaryl coenzyme A synthaseHomo sapiens (human)
Acetoacetyl-CoA synthetaseEC 6.2.1.16; Acyl-CoA synthetase family member 1; Protein sur-5 homologHomo sapiens (human)
Acetyl-CoA acetyltransferase, mitochondrialEC 2.3.1.9; Acetoacetyl-CoA thiolase; T2Homo sapiens (human)
Hydroxymethylglutaryl-CoA lyase, mitochondrialHL; HMG-CoA lyase; EC 4.1.3.4; 3-hydroxy-3-methylglutarate-CoA lyaseHomo sapiens (human)
D-beta-hydroxybutyrate dehydrogenase, mitochondrialEC 1.1.1.30; 3-hydroxybutyrate dehydrogenase; BDH; Short chain dehydrogenase/reductase family 9C member 1Homo sapiens (human)
3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmicEC 4.1.3.4; 3-hydroxy-3-methylglutaryl-CoA lyase-like protein 1; HMGCL-like 1; Endoplasmic reticulum 3-hydroxy-3-methylglutaryl-CoA lyase; er-cHLHomo sapiens (human)
Acyl-CoA synthetase short-chain family member 3, mitochondrialEC 6.2.1.1; Acetate--CoA ligase 3; Acyl-CoA synthetase short-chain family member 3; Propionate--CoA ligase; 6.2.1.17Homo sapiens (human)

Compounds (13)

CompoundDescription
hydronium ion
NADH
MagnesiumA metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION.
adenosine monophosphateAdenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position.
nadA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
3-hydroxy-3-methylglutaryl-coenzyme aRN given refers to cpd without isomeric designation
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
acetoacetate
3-hydroxybutyric acidBUTYRIC ACID substituted in the beta or 3 position. It is one of the ketone bodies produced in the liver.
acetoacetic acid
Coenzyme A
acetoacetyl CoA
Acetyl Coenzyme AAcetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.