Pathways > Synthesis of IP3 and IP4 in the cytosol
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Synthesis of IP3 and IP4 in the cytosol

Proteins (20)

ProteinSynonymsTaxonomy
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1EC 3.1.4.11; Phosphoinositide phospholipase C-delta-1; Phospholipase C-III; PLC-III; Phospholipase C-delta-1; PLC-delta-1Homo sapiens (human)
Inositol-trisphosphate 3-kinase AEC 2.7.1.127; Inositol 1,4,5-trisphosphate 3-kinase A; IP3 3-kinase A; IP3K A; InsP 3-kinase AHomo sapiens (human)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1EC 3.1.4.11; PLC-148; Phosphoinositide phospholipase C-gamma-1; Phospholipase C-II; PLC-II; Phospholipase C-gamma-1; PLC-gamma-1Homo sapiens (human)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2EC 3.1.4.11; Phosphoinositide phospholipase C-gamma-2; Phospholipase C-IV; PLC-IV; Phospholipase C-gamma-2; PLC-gamma-2Homo sapiens (human)
Inositol-tetrakisphosphate 1-kinaseEC 2.7.1.134; Inositol 1,3,4-trisphosphate 5/6-kinase; Inositol-triphosphate 5/6-kinase; Ins(1,3,4)P(3) 5/6-kinase; 2.7.1.159Homo sapiens (human)
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTENEC 3.1.3.16; EC 3.1.3.48; EC 3.1.3.67; Mutated in multiple advanced cancers 1; Phosphatase and tensin homologHomo sapiens (human)
5'-3' exonuclease PLD4EC 3.1.16.1; Choline phosphatase 4; Phosphatidylcholine-hydrolyzing phospholipase D4; Phospholipase D family member 4; Phospholipase D4; PLD 4Homo sapiens (human)
Calmodulin-1Homo sapiens (human)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1EC 3.1.4.11; PLC-154; Phosphoinositide phospholipase C-beta-1; Phospholipase C-I; PLC-I; Phospholipase C-beta-1; PLC-beta-1Homo sapiens (human)
Inositol-trisphosphate 3-kinase BEC 2.7.1.127; Inositol 1,4,5-trisphosphate 3-kinase B; IP3 3-kinase B; IP3K B; InsP 3-kinase BHomo sapiens (human)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2EC 3.1.4.11; Phosphoinositide phospholipase C-beta-2; Phospholipase C-beta-2; PLC-beta-2Homo sapiens (human)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2EC 3.1.4.11; Phosphoinositide phospholipase C-eta-2; Phosphoinositide phospholipase C-like 4; PLC-L4; Phospholipase C-like protein 4; Phospholipase C-eta-2; PLC-eta2Homo sapiens (human)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4hPLCD4; EC 3.1.4.11; Phosphoinositide phospholipase C-delta-4; Phospholipase C-delta-4; PLC-delta-4Homo sapiens (human)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4EC 3.1.4.11; Phosphoinositide phospholipase C-beta-4; Phospholipase C-beta-4; PLC-beta-4Homo sapiens (human)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1EC 3.1.4.11; Pancreas-enriched phospholipase C; Phosphoinositide phospholipase C-epsilon-1; Phospholipase C-epsilon-1; PLC-epsilon-1Homo sapiens (human)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3EC 3.1.4.11; Phosphoinositide phospholipase C-beta-3; Phospholipase C-beta-3; PLC-beta-3Homo sapiens (human)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1EC 3.1.4.11; Phosphoinositide phospholipase C-eta-1; Phospholipase C-eta-1; PLC-eta-1; Phospholipase C-like protein 3; PLC-L3Homo sapiens (human)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1EC 3.1.4.11; Phosphoinositide phospholipase C-zeta-1; Phospholipase C-zeta-1; PLC-zeta-1; Testis-development protein NYD-SP27Homo sapiens (human)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3EC 3.1.4.11; Phosphoinositide phospholipase C-delta-3; Phospholipase C-delta-3; PLC-delta-3Homo sapiens (human)
Inositol-trisphosphate 3-kinase CEC 2.7.1.127; Inositol 1,4,5-trisphosphate 3-kinase C; IP3 3-kinase C; IP3K C; InsP 3-kinase CHomo sapiens (human)

Compounds (10)

CompoundDescription
CalciumA basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
Orthophosphate
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
MagnesiumA metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
inositol 1,4,6-trisphosphateinhibits (1,4,5)P3/(1,3,4,5)P4-polyphosphate 5-phosphatase; structure in first source
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
Nalidixic AcidA synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum. It is an inhibitor of the A subunit of bacterial DNA GYRASE.
inositol-1,3,4,6-tetrakisphosphatefor cpd without numerical locants of phosphate groups, index INOSITOL PHOSPHATES
inositol 1,3,4-trisphosphate