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Synthesis of IP2, IP, and Ins in the cytosol

Proteins (5)

ProteinSynonymsTaxonomy
Inositol oxygenaseEC 1.13.99.1; Aldehyde reductase-like 6; Kidney-specific protein 32; Myo-inositol oxygenase; MI oxygenase; Renal-specific oxidoreductaseHomo sapiens (human)
Myotubularin-related protein 7Inositol 1,3-bisphosphate phosphatase; 3.1.3.-; Phosphatidylinositol-3-phosphate phosphatase; 3.1.3.64Homo sapiens (human)
Inositol polyphosphate 1-phosphataseIPP; IPPase; EC 3.1.3.57Homo sapiens (human)
Myotubularin-related protein 9Inactive phosphatidylinositol 3-phosphatase 9Homo sapiens (human)
Inositol-3-phosphate synthase 1IPS 1; EC 5.5.1.4; Myo-inositol 1-phosphate synthase; MI-1-P synthase; MIP synthase; hIPS; Myo-inositol 1-phosphate synthase A1; hINO1Homo sapiens (human)

Compounds (16)

CompoundDescription
hydronium ion
inositol 1-phosphate
ironA metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN.
Orthophosphate
MagnesiumA metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION.
inositolAn isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
OxygenAn element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
nadA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
inositol 1,4-bis(phosphate)induced in human platelets by thrombin; RN given refers to cpd without isomeric designation
inositol 4-phosphateRN given refers to (DL-myo)-isomer
inositol 3-phosphateRN given refers to (myo)-isomer
inositol 3,4-bisphosphateRN given for (D)-isomer
Glucose-6-PhosphateAn ester of glucose with phosphoric acid, made in the course of glucose metabolism by mammalian and other cells. It is a normal constituent of resting muscle and probably is in constant equilibrium with fructose-6-phosphate. (Stedman, 26th ed)
inositol 1,3-bisphosphate
inositol 1,3,4-trisphosphate