Page last updated: 2024-10-06
Sulfur compound metabolism
Proteins (19)
| Protein | Synonyms | Taxonomy |
|---|---|---|
| O-acetylserine sulfhydrylase | OAS sulfhydrylase; OASS; EC 2.5.1.47; Cysteine synthase A; CSase A; O-acetylserine (thiol)-lyase A; OAS-TL A; O-acetylserine-specific cysteine synthase; Sulfide-dependent cysteine synthase | Mycobacterium tuberculosis H37Rv |
| 3'-phosphoadenosine 5'-phosphate phosphatase | PAP phosphatase; EC 3.1.3.7; 3'(2'),5'-bisphosphate nucleotidase; 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; D-fructose-1,6-bisphosphate 1-phosphohydrolase; DPNPase; Fructose-1,6-bisphosphatase; FBPase; 3.1.3.11; Inositol-1-monophosphatase; I- | Mycobacterium tuberculosis H37Rv |
| Thioredoxin | Trx; MPT46 | Mycobacterium tuberculosis H37Rv |
| Cystathionine gamma-synthase | CGS; EC 2.5.1.48; O-succinylhomoserine (thiol)-lyase | Mycobacterium tuberculosis H37Rv |
| Probable phosphoadenosine phosphosulfate reductase | EC 1.8.4.8; 3'-phosphoadenylylsulfate reductase; PAPS reductase, thioredoxin dependent; PAPS sulfotransferase; PAdoPS reductase | Mycobacterium tuberculosis H37Rv |
| S-sulfocysteine synthase | EC 2.8.5.1; O-phospho-L-serine-dependent S-sulfocysteine synthase; OPS-dependent S-sulfocysteine synthase; O-phosphoserine sulfhydrylase; 2.5.1.65 | Mycobacterium tuberculosis H37Rv |
| Serine acetyltransferase | SAT; EC 2.3.1.30 | Mycobacterium tuberculosis H37Rv |
| CysO-cysteine peptidase | EC 3.13.1.6; Metallocarboxypeptidase Mec | Mycobacterium tuberculosis H37Rv |
| Sulfate adenylyltransferase subunit 2 | EC 2.7.7.4; ATP-sulfurylase small subunit; Sulfate adenylate transferase; SAT | Mycobacterium tuberculosis H37Rv |
| Sulfite reductase [ferredoxin] | EC 1.8.7.1 | Mycobacterium tuberculosis H37Rv |
| Probable adenylyltransferase/sulfurtransferase MoeZ | Mycobacterium tuberculosis H37Rv | |
| O-phosphoserine sulfhydrylase | OPS sulfhydrylase; EC 2.5.1.113; CysO-thiocarboxylate-dependent cysteine synthase; Cysteine synthase B; CSase B; O-phosphoserine-specific cysteine synthase; [CysO sulfur-carrier protein]-thiocarboxylate-dependent cysteine synthase | Mycobacterium tuberculosis H37Rv |
| Sulfate/thiosulfate import ATP-binding protein CysA | EC 7.3.2.3; Sulfate-transporting ATPase | Mycobacterium tuberculosis H37Rv |
| Probable sulfate-transport integral membrane protein ABC transporter CysW | Mycobacterium tuberculosis H37Rv | |
| Probable sulfate-binding lipoprotein SubI | Mycobacterium tuberculosis H37Rv | |
| Bifunctional enzyme CysN/CysC | Mycobacterium tuberculosis H37Rv | |
| Ferredoxin | Mycobacterium tuberculosis H37Rv | |
| Sulfur carrier protein CysO | 9.5 kDa culture filtrate antigen cfp10A | Mycobacterium tuberculosis H37Rv |
| Sulfate transport system permease protein CysT | Mycobacterium tuberculosis H37Rv |
Compounds (24)
| Compound | Description |
|---|---|
| diphosphoric acid | |
| hydronium ion | |
| pyridoxal phosphate | This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE). |
| Orthophosphate | |
| acetic acid | Product of the oxidation of ethanol and of the destructive distillation of wood. It is used locally, occasionally internally, as a counterirritant and also as a reagent. (Stedman, 26th ed) |
| ammonium hydroxide | The hydroxy salt of ammonium ion. It is formed when AMMONIA reacts with water molecules in solution. |
| Sulfur | An element that is a member of the chalcogen family. It has an atomic symbol S, atomic number 16, and atomic weight [32.059; 32.076]. It is found in the amino acids cysteine and methionine. |
| Zinc | A metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn. |
| Adenosine Triphosphate | An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter. |
| adenosine diphosphate | Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position. |
| adenosine monophosphate | Adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position. |
| Magnesium | A metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION. |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| guanosine diphosphate | A guanine nucleotide containing two phosphate groups esterified to the sugar moiety. |
| guanosine triphosphate | Guanosine 5'-(tetrahydrogen triphosphate). A guanine nucleotide containing three phosphate groups esterified to the sugar moiety. |
| siroheme | the heme prosthetic group of the hemoprotein of E coli NADPH-sulfite reductase; reduces sulfite to sulfide or nitrite to ammonia; structure |
| alpha-ketobutyric acid | RN given refers to parent cpd; structure |
| Cysteine | A thiol-containing non-essential amino acid that is oxidized to form CYSTINE. |
| poly-o-acetylserine | |
| phosphoadenosine phosphosulfate | 3'-Phosphoadenosine-5'-phosphosulfate. Key intermediate in the formation by living cells of sulfate esters of phenols, alcohols, steroids, sulfated polysaccharides, and simple esters, such as choline sulfate. It is formed from sulfate ion and ATP in a two-step process. This compound also is an important step in the process of sulfur fixation in plants and microorganisms. |
| adenosine phosphosulfate | 5'-Adenylic acid, monoanhydride with sulfuric acid. The initial compound formed by the action of ATP sulfurylase on sulfate ions after sulfate uptake. Synonyms: adenosine sulfatophosphate; APS. |
| acetyl coenzyme a | Acetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent. |
| plasmenylserine | RN given refers to (L)-isomer |
| coenzyme a |