Pathways > Sphingolipid metabolism overview
Page last updated: 2024-10-06
Sphingolipid metabolism overview
Proteins (4)
| Protein | Synonyms | Taxonomy |
|---|
| Sphingomyelin phosphodiesterase | EC 3.1.4.12; Acid sphingomyelinase; aSMase | Homo sapiens (human) |
| Ceramide glucosyltransferase | EC 2.4.1.80; GLCT-1; Glucosylceramide synthase; GCS; UDP-glucose ceramide glucosyltransferase; UDP-glucose:N-acylsphingosine D-glucosyltransferase | Homo sapiens (human) |
| Phosphatidylcholine:ceramide cholinephosphotransferase 2 | EC 2.7.8.27; Sphingomyelin synthase 2 | Homo sapiens (human) |
| 3-ketodihydrosphingosine reductase | KDS reductase; EC 1.1.1.102; 3-dehydrosphinganine reductase; Follicular variant translocation protein 1; FVT-1; Short chain dehydrogenase/reductase family 35C member 1 | Homo sapiens (human) |
Compounds (15)
| Compound | Description |
|---|
| adenosine diphosphate | Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position. |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| phosphorylethanolamine | RN given refers to parent cpd; structure |
| arachidoyl-coenzyme a | |
| ketodihydrosphingosine | RN given refers to cpd without isomeric designation |
| sphingosine | An amino alcohol with a long unsaturated hydrocarbon chain. Sphingosine and its derivative sphinganine are the major bases of the sphingolipids in mammals. (Dorland, 28th ed) |
| 2-hexadecenal | |
| sphingosine 1-phosphate | RN given refers to (R-(R*,S*-(E)))-isomer; RN for cpd without isomeric designation not available 8/89 |
| adenosine triphosphate | An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter. |
| serine | A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids. |
| hexadecanal | |
| palmitoyl coenzyme a | A fatty acid coenzyme derivative which plays a key role in fatty acid oxidation and biosynthesis. |
| dihydrosphingosine 1-phosphate | RN given refers to (R-(R*,S*))-isomer |
| mephentermine | A sympathomimetic agent with specificity for alpha-1 adrenergic receptors. It is used to maintain BLOOD PRESSURE in hypotensive states such as following SPINAL ANESTHESIA. |
| stearoyl-coenzyme a | |