Sphingolipid metabolism in senescence

Proteins (9)

Protein	Synonyms	Taxonomy
Protein kinase C beta type	PKC-B; PKC-beta; EC 2.7.11.13	Homo sapiens (human)
Protein kinase C alpha type	PKC-A; PKC-alpha; EC 2.7.11.13	Homo sapiens (human)
Serine palmitoyltransferase 1	EC 2.3.1.50; Long chain base biosynthesis protein 1; LCB 1; Serine-palmitoyl-CoA transferase 1; SPT 1; SPT1	Homo sapiens (human)
Telomerase reverse transcriptase	EC 2.7.7.49; HEST2; Telomerase catalytic subunit; Telomerase-associated protein 2; TP2	Homo sapiens (human)
Ceramide glucosyltransferase	EC 2.4.1.80; GLCT-1; Glucosylceramide synthase; GCS; UDP-glucose ceramide glucosyltransferase; UDP-glucose:N-acylsphingosine D-glucosyltransferase	Homo sapiens (human)
3-ketodihydrosphingosine reductase	KDS reductase; EC 1.1.1.102; 3-dehydrosphinganine reductase; Follicular variant translocation protein 1; FVT-1; Short chain dehydrogenase/reductase family 35C member 1	Homo sapiens (human)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase		Homo sapiens (human)
Cyclin-dependent kinase inhibitor 1A		Homo sapiens (human)
Glucosylceramidase		Homo sapiens (human)

Compound	Description
ketodihydrosphingosine	RN given refers to cpd without isomeric designation
sphingosine 1-phosphate	RN given refers to (R-(R,S-(E)))-isomer; RN for cpd without isomeric designation not available 8/89
Serine	A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
palmitoyl coenzyme a	A fatty acid coenzyme derivative which plays a key role in fatty acid oxidation and biosynthesis.
mephentermine	A sympathomimetic agent with specificity for alpha-1 adrenergic receptors. It is used to maintain BLOOD PRESSURE in hypotensive states such as following SPINAL ANESTHESIA.