Page last updated: 2024-10-06

Sphingolipid catabolism

Proteins (7)

ProteinSynonymsTaxonomy
Alkaline ceramidase 2AlkCDase 2; Alkaline CDase 2; haCER2; EC 3.5.1.-; EC 3.5.1.23; Acylsphingosine deacylase 3-like; N-acylsphingosine amidohydrolase 3-likeHomo sapiens (human)
Sphingosine-1-phosphate lyase 1S1PL; SP-lyase 1; SPL 1; hSPL; EC 4.1.2.27; Sphingosine-1-phosphate aldolaseHomo sapiens (human)
Alkaline ceramidase 1AlkCDase 1; Alkaline CDase 1; EC 3.5.1.-; EC 3.5.1.23; Acylsphingosine deacylase 3; N-acylsphingosine amidohydrolase 3Homo sapiens (human)
Aldehyde dehydrogenase family 3 member B2EC 1.2.1.3; Aldehyde dehydrogenase 8Homo sapiens (human)
Aldehyde dehydrogenase family 3 member B1EC 1.2.1.28; EC 1.2.1.5; EC 1.2.1.7; Aldehyde dehydrogenase 7Homo sapiens (human)
Phospholipid phosphatase 1EC 3.1.3.-; EC 3.1.3.106; EC 3.1.3.4; EC 3.1.3.81; Lipid phosphate phosphohydrolase 1; PAP2-alpha; Phosphatidate phosphohydrolase type 2a; Phosphatidic acid phosphatase 2a; PAP-2a; PAP2aHomo sapiens (human)
Alkaline ceramidase 3AlkCDase 3; Alkaline CDase 3; EC 3.5.1.-; EC 3.5.1.23; Alkaline dihydroceramidase SB89; Alkaline phytoceramidase; aPHCHomo sapiens (human)

Compounds (14)

CompoundDescription
hydronium ion
NADH
CalciumA basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
ZincA metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn.
Orthophosphate
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
palmitic acidA common saturated fatty acid found in fats and waxes including olive oil, palm oil, and body lipids.
phytosphingosinediffer with an additional hydroxyl at C-4 & no double bond between C-4 & C-5
phosphorylethanolamineRN given refers to parent cpd; structure
nadA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
2-hexadecenal
hexadecanal
SphingosineAn amino alcohol with a long unsaturated hydrocarbon chain. Sphingosine and its derivative sphinganine are the major bases of the sphingolipids in mammals. (Dorland, 28th ed)
sphingosine 1-phosphateRN given refers to (R-(R*,S*-(E)))-isomer; RN for cpd without isomeric designation not available 8/89