| Protein | Synonyms | Taxonomy |
|---|
| Myosin light chain kinase, smooth muscle | MLCK; smMLCK; EC 2.7.11.18; Kinase-related protein; KRP; Telokin | Homo sapiens (human) |
| Paxillin | | Homo sapiens (human) |
| cGMP-specific 3',5'-cyclic phosphodiesterase | EC 3.1.4.35; cGMP-binding cGMP-specific phosphodiesterase; CGB-PDE | Homo sapiens (human) |
| Integrin beta-5 | | Homo sapiens (human) |
| Aldehyde dehydrogenase, mitochondrial | EC 1.2.1.3; ALDH class 2; ALDH-E2; ALDHI | Homo sapiens (human) |
| Annexin A2 | Annexin II; Annexin-2; Calpactin I heavy chain; Calpactin-1 heavy chain; Chromobindin-8; Lipocortin II; Placental anticoagulant protein IV; PAP-IV; Protein I; p36 | Homo sapiens (human) |
| Integrin alpha-1 | CD49 antigen-like family member A; Laminin and collagen receptor; VLA-1 | Homo sapiens (human) |
| Calmodulin-1 | | Homo sapiens (human) |
| Annexin A1 | Annexin I; Annexin-1; Calpactin II; Calpactin-2; Chromobindin-9; Lipocortin I; Phospholipase A2 inhibitory protein; p35 | Homo sapiens (human) |
| Leiomodin-1 | 64 kDa autoantigen 1D; 64 kDa autoantigen 1D3; 64 kDa autoantigen D1; Leiomodin, muscle form; Smooth muscle leiomodin; SM-Lmod; Thyroid-associated ophthalmopathy autoantigen | Homo sapiens (human) |
| Sorbin and SH3 domain-containing protein 1 | Ponsin; SH3 domain protein 5; SH3P12; c-Cbl-associated protein; CAP | Homo sapiens (human) |
| Vinculin | Metavinculin; MV | Homo sapiens (human) |
| Dysferlin | Dystrophy-associated fer-1-like protein; Fer-1-like protein 1 | Homo sapiens (human) |
| Caldesmon | CDM | Homo sapiens (human) |
| Annexin A6 | 67 kDa calelectrin; Annexin VI; Annexin-6; Calphobindin-II; CPB-II; Chromobindin-20; Lipocortin VI; Protein III; p68; p70 | Homo sapiens (human) |
| Caveolin-3 | M-caveolin | Homo sapiens (human) |
| Vinexin | SH3-containing adapter molecule 1; SCAM-1; Sorbin and SH3 domain-containing protein 3 | Homo sapiens (human) |
| Myosin-11 | Myosin heavy chain 11; Myosin heavy chain, smooth muscle isoform; SMMHC | Homo sapiens (human) |
| Tripartite motif-containing protein 72 | Mitsugumin-53; Mg53 | Homo sapiens (human) |
| Talin-1 | | Homo sapiens (human) |
| Compound | Description |
|---|
| hydronium ion | |
| Nitric Oxide | A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP. |
| Calcium | A basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes. |
| carbon monoxide | Carbon monoxide (CO). A poisonous colorless, odorless, tasteless gas. It combines with hemoglobin to form carboxyhemoglobin, which has no oxygen carrying capacity. The resultant oxygen deprivation causes headache, dizziness, decreased pulse and respiratory rates, unconsciousness, and death. (From Merck Index, 11th ed) |
| Orthophosphate | |
| nitroglycerin | A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives. |
| adenosine diphosphate | Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position. |
| Magnesium | A metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION. |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| Guanosine Monophosphate | A guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature. |
| cyclic gmp | Guanosine cyclic 3',5'-(hydrogen phosphate). A guanine nucleotide containing one phosphate group which is esterified to the sugar moiety in both the 3'- and 5'-positions. It is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones, including acetylcholine, insulin, and oxytocin and it has been found to activate specific protein kinases. (From Merck Index, 11th ed) |
| adenosine triphosphate | An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter. |
| glyceryl 1,2-dinitrate | |
| bay 58-2667 | activates guanylyl cyclase; structure in first source |