Page last updated: 2024-10-06

Signaling events regulated by Ret tyrosine kinase

Proteins (38)

ProteinSynonymsTaxonomy
Insulin receptor substrate 1IRS-1Homo sapiens (human)
Proto-oncogene tyrosine-protein kinase receptor RetEC 2.7.10.1; Cadherin family member 12; Proto-oncogene c-RetHomo sapiens (human)
Proto-oncogene tyrosine-protein kinase SrcEC 2.7.10.2; Proto-oncogene c-Src; pp60c-src; p60-SrcHomo sapiens (human)
Protein kinase C alpha typePKC-A; PKC-alpha; EC 2.7.11.13Homo sapiens (human)
Mitogen-activated protein kinase 3 MAP kinase 3; MAPK 3; EC 2.7.11.24; ERT2; Extracellular signal-regulated kinase 1; ERK-1; Insulin-stimulated MAP2 kinase; MAP kinase isoform p44; p44-MAPK; Microtubule-associated protein 2 kinase; p44-ERK1Homo sapiens (human)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformPI3-kinase subunit alpha; PI3K-alpha; PI3Kalpha; PtdIns-3-kinase subunit alpha; EC 2.7.1.137; EC 2.7.1.153; Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha; PtdIns-3-kinase subunit p110-alpha; p110alpha; Phosphoinositide 3-kHomo sapiens (human)
Focal adhesion kinase 1FADK 1; EC 2.7.10.2; Focal adhesion kinase-related nonkinase; FRNK; Protein phosphatase 1 regulatory subunit 71; PPP1R71; Protein-tyrosine kinase 2; p125FAK; pp125FAKHomo sapiens (human)
Tyrosine-protein phosphatase non-receptor type 11EC 3.1.3.48; Protein-tyrosine phosphatase 1D; PTP-1D; Protein-tyrosine phosphatase 2C; PTP-2C; SH-PTP2; SHP-2; Shp2; SH-PTP3Homo sapiens (human)
PaxillinHomo sapiens (human)
Transcription factor AP-1Activator protein 1; AP1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog; p39Homo sapiens (human)
cAMP-dependent protein kinase catalytic subunit alphaPKA C-alpha; EC 2.7.11.11Homo sapiens (human)
Phosphatidylinositol 3-kinase regulatory subunit alphaPI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; PI3-kinase subunit p85-alpha; PtdIns-3-kinase regulatory subunit p85-alphaHomo sapiens (human)
SHC-transforming protein 1SHC-transforming protein 3; SHC-transforming protein A; Src homology 2 domain-containing-transforming protein C1; SH2 domain protein C1Homo sapiens (human)
Mitogen-activated protein kinase 8MAP kinase 8; MAPK 8; EC 2.7.11.24; JNK-46; Stress-activated protein kinase 1c; SAPK1c; Stress-activated protein kinase JNK1; c-Jun N-terminal kinase 1Homo sapiens (human)
Growth factor receptor-bound protein 2Adapter protein GRB2; Protein Ash; SH2/SH3 adapter GRB2Homo sapiens (human)
Growth factor receptor-bound protein 10GRB10 adapter protein; Insulin receptor-binding protein Grb-IRHomo sapiens (human)
Cytoplasmic protein NCK1NCK adaptor protein 1; Nck-1; SH2/SH3 adaptor protein NCK-alphaHomo sapiens (human)
Cyclic AMP-responsive element-binding protein 1CREB-1; cAMP-responsive element-binding protein 1Homo sapiens (human)
Adapter molecule crkProto-oncogene c-Crk; p38Homo sapiens (human)
Ras-related C3 botulinum toxin substrate 1EC 3.6.5.2; Cell migration-inducing gene 5 protein; Ras-like protein TC25; p21-Rac1Homo sapiens (human)
Growth factor receptor-bound protein 7B47; Epidermal growth factor receptor GRB-7; GRB7 adapter proteinHomo sapiens (human)
Son of sevenless homolog 1SOS-1Homo sapiens (human)
GRB2-associated-binding protein 1GRB2-associated binder 1; Growth factor receptor bound protein 2-associated protein 1Homo sapiens (human)
GTPase HRasEC 3.6.5.2; H-Ras-1; Ha-Ras; Transforming protein p21; c-H-ras; p21rasHomo sapiens (human)
Transforming protein RhoAEC 3.6.5.2; Rho cDNA clone 12; h12Homo sapiens (human)
Ras-related protein Rap-1AEC 3.6.5.2; C21KG; G-22K; GTP-binding protein smg p21A; Ras-related protein Krev-1Homo sapiens (human)
Glial cell line-derived neurotrophic factorhGDNF; Astrocyte-derived trophic factor; ATFHomo sapiens (human)
PDZ and LIM domain protein 7LIM mineralization protein; LMP; Protein enigmaHomo sapiens (human)
Breast cancer anti-estrogen resistance protein 1CRK-associated substrate; Cas scaffolding protein family member 1; p130casHomo sapiens (human)
SH3 and multiple ankyrin repeat domains protein 3Shank3; Proline-rich synapse-associated protein 2; ProSAP2Homo sapiens (human)
Ras GTPase-activating protein 1GAP; GTPase-activating protein; RasGAP; Ras p21 protein activator; p120GAPHomo sapiens (human)
GDNF family receptor alpha-1GDNF receptor alpha-1; GDNFR-alpha-1; GFR-alpha-1; RET ligand 1; TGF-beta-related neurotrophic factor receptor 1Homo sapiens (human)
Docking protein 6Downstream of tyrosine kinase 6Homo sapiens (human)
Docking protein 4Downstream of tyrosine kinase 4; Insulin receptor substrate 5; IRS-5; IRS5Homo sapiens (human)
Fibroblast growth factor receptor substrate 2FGFR substrate 2; FGFR-signaling adaptor SNT; Suc1-associated neurotrophic factor target 1; SNT-1Homo sapiens (human)
Docking protein 1Downstream of tyrosine kinase 1; p62(dok); pp62Homo sapiens (human)
Docking protein 5Downstream of tyrosine kinase 5; Insulin receptor substrate 6; IRS-6; IRS6Homo sapiens (human)
Insulin receptor substrate 2IRS-2Homo sapiens (human)

Compounds (0)

CompoundDescription