Page last updated: 2024-10-06

Signaling events mediated by focal adhesion kinase

Proteins (54)

ProteinSynonymsTaxonomy
Tyrosine-protein phosphatase non-receptor type 21EC 3.1.3.48; Protein-tyrosine phosphatase D1Homo sapiens (human)
Rho-associated protein kinase 2EC 2.7.11.1; Rho kinase 2; Rho-associated, coiled-coil-containing protein kinase 2; Rho-associated, coiled-coil-containing protein kinase II; ROCK-II; p164 ROCK-2Homo sapiens (human)
RAF proto-oncogene serine/threonine-protein kinaseEC 2.7.11.1; Proto-oncogene c-RAF; cRaf; Raf-1Homo sapiens (human)
Integrin beta-1Fibronectin receptor subunit beta; Glycoprotein IIa; GPIIA; VLA-4 subunit betaHomo sapiens (human)
Tyrosine-protein kinase LckEC 2.7.10.2; Leukocyte C-terminal Src kinase; LSK; Lymphocyte cell-specific protein-tyrosine kinase; Protein YT16; Proto-oncogene Lck; T cell-specific protein-tyrosine kinase; p56-LCKHomo sapiens (human)
Proto-oncogene tyrosine-protein kinase SrcEC 2.7.10.2; Proto-oncogene c-Src; pp60c-src; p60-SrcHomo sapiens (human)
Serine/threonine-protein kinase B-rafEC 2.7.11.1; Proto-oncogene B-Raf; p94; v-Raf murine sarcoma viral oncogene homolog B1Homo sapiens (human)
G1/S-specific cyclin-D1B-cell lymphoma 1 protein; BCL-1; BCL-1 oncogene; PRAD1 oncogeneHomo sapiens (human)
Mitogen-activated protein kinase 1MAP kinase 1; MAPK 1; EC 2.7.11.24; ERT1; Extracellular signal-regulated kinase 2; ERK-2; MAP kinase isoform p42; p42-MAPK; Mitogen-activated protein kinase 2; MAP kinase 2; MAPK 2Homo sapiens (human)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformPI3-kinase subunit alpha; PI3K-alpha; PI3Kalpha; PtdIns-3-kinase subunit alpha; EC 2.7.1.137; EC 2.7.1.153; Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha; PtdIns-3-kinase subunit p110-alpha; p110alpha; Phosphoinositide 3-kHomo sapiens (human)
Dual specificity mitogen-activated protein kinase kinase 1MAP kinase kinase 1; MAPKK 1; MKK1; EC 2.7.12.2; ERK activator kinase 1; MAPK/ERK kinase 1; MEK 1Homo sapiens (human)
Focal adhesion kinase 1FADK 1; EC 2.7.10.2; Focal adhesion kinase-related nonkinase; FRNK; Protein phosphatase 1 regulatory subunit 71; PPP1R71; Protein-tyrosine kinase 2; p125FAK; pp125FAKHomo sapiens (human)
Serine/threonine-protein kinase PAK 1EC 2.7.11.1; Alpha-PAK; p21-activated kinase 1; PAK-1; p65-PAKHomo sapiens (human)
Myosin light chain kinase, smooth muscleMLCK; smMLCK; EC 2.7.11.18; Kinase-related protein; KRP; TelokinHomo sapiens (human)
Rho guanine nucleotide exchange factor 11PDZ-RhoGEFHomo sapiens (human)
Dedicator of cytokinesis protein 1180 kDa protein downstream of CRK; DOCK180Homo sapiens (human)
Rho GTPase-activating protein 35Glucocorticoid receptor DNA-binding factor 1; Glucocorticoid receptor repression factor 1; GRF-1; Rho GAP p190A; p190-AHomo sapiens (human)
PaxillinHomo sapiens (human)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1EC 3.1.4.11; PLC-148; Phosphoinositide phospholipase C-gamma-1; Phospholipase C-II; PLC-II; Phospholipase C-gamma-1; PLC-gamma-1Homo sapiens (human)
Transcription factor AP-1Activator protein 1; AP1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog; p39Homo sapiens (human)
Integrin alpha-V Vitronectin receptor; Vitronectin receptor subunit alphaHomo sapiens (human)
Integrin beta-5Homo sapiens (human)
Phosphatidylinositol 3-kinase regulatory subunit alphaPI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; PI3-kinase subunit p85-alpha; PtdIns-3-kinase regulatory subunit p85-alphaHomo sapiens (human)
Mitogen-activated protein kinase 8MAP kinase 8; MAPK 8; EC 2.7.11.24; JNK-46; Stress-activated protein kinase 1c; SAPK1c; Stress-activated protein kinase JNK1; c-Jun N-terminal kinase 1Homo sapiens (human)
Cytoplasmic tyrosine-protein kinase BMXEC 2.7.10.2; Bone marrow tyrosine kinase gene in chromosome X protein; Epithelial and endothelial tyrosine kinase; ETK; NTK38Homo sapiens (human)
Growth factor receptor-bound protein 2Adapter protein GRB2; Protein Ash; SH2/SH3 adapter GRB2Homo sapiens (human)
Cytoplasmic protein NCK1NCK adaptor protein 1; Nck-1; SH2/SH3 adaptor protein NCK-alphaHomo sapiens (human)
Adapter molecule crkProto-oncogene c-Crk; p38Homo sapiens (human)
Ras-related C3 botulinum toxin substrate 1EC 3.6.5.2; Cell migration-inducing gene 5 protein; Ras-like protein TC25; p21-Rac1Homo sapiens (human)
Growth factor receptor-bound protein 7B47; Epidermal growth factor receptor GRB-7; GRB7 adapter proteinHomo sapiens (human)
Son of sevenless homolog 1SOS-1Homo sapiens (human)
Rap guanine nucleotide exchange factor 1CRK SH3-binding GNRP; Guanine nucleotide-releasing factor 2; Protein C3GHomo sapiens (human)
Integrin alpha-5CD49 antigen-like family member E; Fibronectin receptor subunit alpha; Integrin alpha-F; VLA-5Homo sapiens (human)
Calpain-2 catalytic subunitEC 3.4.22.53; Calcium-activated neutral proteinase 2; CANP 2; Calpain M-type; Calpain large polypeptide L2; Calpain-2 large subunit; Millimolar-calpain; M-calpainHomo sapiens (human)
Dual specificity mitogen-activated protein kinase kinase 4MAP kinase kinase 4; MAPKK 4; EC 2.7.12.2; JNK-activating kinase 1; MAPK/ERK kinase 4; MEK 4; SAPK/ERK kinase 1; SEK1; Stress-activated protein kinase kinase 1; SAPK kinase 1; SAPKK-1; SAPKK1; c-Jun N-terminal kinase kinase 1; JNKKHomo sapiens (human)
Transforming protein RhoAEC 3.6.5.2; Rho cDNA clone 12; h12Homo sapiens (human)
VinculinMetavinculin; MVHomo sapiens (human)
Breast cancer anti-estrogen resistance protein 1CRK-associated substrate; Cas scaffolding protein family member 1; p130casHomo sapiens (human)
Ras GTPase-activating protein 1GAP; GTPase-activating protein; RasGAP; Ras p21 protein activator; p120GAPHomo sapiens (human)
Neural Wiskott-Aldrich syndrome proteinN-WASPHomo sapiens (human)
Krueppel-like factor 8Basic krueppel-like factor 3; Zinc finger protein 741Homo sapiens (human)
Ras-related protein R-RasEC 3.6.5.-; p23Homo sapiens (human)
Alpha-actinin-1Alpha-actinin cytoskeletal isoform; F-actin cross-linking protein; Non-muscle alpha-actinin-1Homo sapiens (human)
Protein C-ets-1p54Homo sapiens (human)
Actin, alpha skeletal muscleAlpha-actin-1Homo sapiens (human)
Rho guanine nucleotide exchange factor 7Beta-Pix; COOL-1; PAK-interacting exchange factor beta; p85Homo sapiens (human)
ARF GTPase-activating protein GIT2ARF GAP GIT2; Cool-interacting tyrosine-phosphorylated protein 2; CAT-2; CAT2; G protein-coupled receptor kinase-interactor 2; GRK-interacting protein 2Homo sapiens (human)
Rho guanine nucleotide exchange factor 28190 kDa guanine nucleotide exchange factor; p190-RhoGEF; p190RhoGEF; Rho guanine nucleotide exchange factorHomo sapiens (human)
Engulfment and cell motility protein 1Protein ced-12 homologHomo sapiens (human)
Endophilin-A2EEN fusion partner of MLL; Endophilin-2; Extra eleven-nineteen leukemia fusion gene protein; EEN; SH3 domain protein 2B; SH3 domain-containing GRB2-like protein 1Homo sapiens (human)
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein; ADP-ribosylation factor-directed GTPase-activating protein 1; ARF GTPase-activating protein 1; Development and differentiation-enhancing factor 1; DEF-1; DifferentiatiHomo sapiens (human)
Rho GTPase-activating protein 26GTPase regulator associated with focal adhesion kinase; Oligophrenin-1-like protein; Rho-type GTPase-activating protein 26Homo sapiens (human)
C-Jun-amino-terminal kinase-interacting protein 3JIP-3; JNK-interacting protein 3; JNK MAP kinase scaffold protein 3; Mitogen-activated protein kinase 8-interacting protein 3Homo sapiens (human)
Talin-1Homo sapiens (human)

Compounds (0)

CompoundDescription