Pathways > Signaling events mediated by Stem cell factor receptor (c-Kit)
Page last updated: 2024-10-06

Signaling events mediated by Stem cell factor receptor (c-Kit)

Proteins (53)

ProteinSynonymsTaxonomy
SH2B adapter protein 2Adapter protein with pleckstrin homology and Src homology 2 domains; SH2 and PH domain-containing adapter protein APSHomo sapiens (human)
3-phosphoinositide-dependent protein kinase 1hPDK1; EC 2.7.11.1Homo sapiens (human)
Tyrosine-protein kinase JAK2EC 2.7.10.2; Janus kinase 2; JAK-2Homo sapiens (human)
RAF proto-oncogene serine/threonine-protein kinaseEC 2.7.11.1; Proto-oncogene c-RAF; cRaf; Raf-1Homo sapiens (human)
Tyrosine-protein kinase LynEC 2.7.10.2; Lck/Yes-related novel protein tyrosine kinase; V-yes-1 Yamaguchi sarcoma viral related oncogene homolog; p53Lyn; p56LynHomo sapiens (human)
Mast/stem cell growth factor receptor KitSCFR; EC 2.7.10.1; Piebald trait protein; PBT; Proto-oncogene c-Kit; Tyrosine-protein kinase Kit; p145 c-kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homologHomo sapiens (human)
Mitogen-activated protein kinase 3 MAP kinase 3; MAPK 3; EC 2.7.11.24; ERT2; Extracellular signal-regulated kinase 1; ERK-1; Insulin-stimulated MAP2 kinase; MAP kinase isoform p44; p44-MAPK; Microtubule-associated protein 2 kinase; p44-ERK1Homo sapiens (human)
RAC-alpha serine/threonine-protein kinaseEC 2.7.11.1; Protein kinase B; PKB; Protein kinase B alpha; PKB alpha; Proto-oncogene c-Akt; RAC-PK-alphaHomo sapiens (human)
Dual specificity mitogen-activated protein kinase kinase 2MAP kinase kinase 2; MAPKK 2; EC 2.7.12.2; ERK activator kinase 2; MAPK/ERK kinase 2; MEK 2Homo sapiens (human)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformPI3-kinase subunit alpha; PI3K-alpha; PI3Kalpha; PtdIns-3-kinase subunit alpha; EC 2.7.1.137; EC 2.7.1.153; Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha; PtdIns-3-kinase subunit p110-alpha; p110alpha; Phosphoinositide 3-kHomo sapiens (human)
Glycogen synthase kinase-3 betaGSK-3 beta; EC 2.7.11.26; Serine/threonine-protein kinase GSK3B; 2.7.11.1Homo sapiens (human)
Dual specificity mitogen-activated protein kinase kinase 1MAP kinase kinase 1; MAPKK 1; MKK1; EC 2.7.12.2; ERK activator kinase 1; MAPK/ERK kinase 1; MEK 1Homo sapiens (human)
Tyrosine-protein phosphatase non-receptor type 11EC 3.1.3.48; Protein-tyrosine phosphatase 1D; PTP-1D; Protein-tyrosine phosphatase 2C; PTP-2C; SH-PTP2; SHP-2; Shp2; SH-PTP3Homo sapiens (human)
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit betaPI3K-C2-beta; PtdIns-3-kinase C2 subunit beta; EC 2.7.1.137; EC 2.7.1.154; C2-PI3K; Phosphoinositide 3-kinase-C2-betaHomo sapiens (human)
Apoptosis regulator Bcl-2Homo sapiens (human)
Tyrosine-protein kinase FerEC 2.7.10.2; Feline encephalitis virus-related kinase FER; Fujinami poultry sarcoma/Feline sarcoma-related protein Fer; Proto-oncogene c-Fer; Tyrosine kinase 3; p94-FerHomo sapiens (human)
Ribosomal protein S6 kinase beta-1S6K-beta-1; S6K1; EC 2.7.11.1; 70 kDa ribosomal protein S6 kinase 1; P70S6K1; p70-S6K 1; Ribosomal protein S6 kinase I; Serine/threonine-protein kinase 14A; p70 ribosomal S6 kinase alpha; p70 S6 kinase alpha; p70 S6K-alpha; p70 S6KAHomo sapiens (human)
Phosphatidylinositol 3-kinase regulatory subunit alphaPI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; PI3-kinase subunit p85-alpha; PtdIns-3-kinase regulatory subunit p85-alphaHomo sapiens (human)
SHC-transforming protein 1SHC-transforming protein 3; SHC-transforming protein A; Src homology 2 domain-containing-transforming protein C1; SH2 domain protein C1Homo sapiens (human)
Signal transducer and activator of transcription 3Acute-phase response factorHomo sapiens (human)
Signal transducer and activator of transcription 5AHomo sapiens (human)
Megakaryocyte-associated tyrosine-protein kinaseEC 2.7.10.2; CSK homologous kinase; CHK; Hematopoietic consensus tyrosine-lacking kinase; Protein kinase HYL; Tyrosine-protein kinase CTKHomo sapiens (human)
Tyrosine-protein kinase TecEC 2.7.10.2Homo sapiens (human)
Mitogen-activated protein kinase 8MAP kinase 8; MAPK 8; EC 2.7.11.24; JNK-46; Stress-activated protein kinase 1c; SAPK1c; Stress-activated protein kinase JNK1; c-Jun N-terminal kinase 1Homo sapiens (human)
Growth factor receptor-bound protein 2Adapter protein GRB2; Protein Ash; SH2/SH3 adapter GRB2Homo sapiens (human)
Bcl2-associated agonist of cell death BAD; Bcl-2-binding component 6; Bcl-2-like protein 8; Bcl2-L-8; Bcl-xL/Bcl-2-associated death promoter; Bcl2 antagonist of cell deathHomo sapiens (human)
Growth factor receptor-bound protein 10GRB10 adapter protein; Insulin receptor-binding protein Grb-IRHomo sapiens (human)
Receptor-type tyrosine-protein phosphatase OR-PTP-O; EC 3.1.3.48; Glomerular epithelial protein 1; Protein tyrosine phosphatase U2; PTP-U2; PTPase U2Homo sapiens (human)
Forkhead box protein O3AF6q21 protein; Forkhead in rhabdomyosarcoma-like 1Homo sapiens (human)
ErythropoietinHomo sapiens (human)
Erythropoietin receptorEPO-RHomo sapiens (human)
Kit ligandMast cell growth factor; MGF; Stem cell factor; SCF; c-Kit ligandHomo sapiens (human)
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTENEC 3.1.3.16; EC 3.1.3.48; EC 3.1.3.67; Mutated in multiple advanced cancers 1; Phosphatase and tensin homologHomo sapiens (human)
Son of sevenless homolog 1SOS-1Homo sapiens (human)
GRB2-associated-binding protein 1GRB2-associated binder 1; Growth factor receptor bound protein 2-associated protein 1Homo sapiens (human)
GTPase HRasEC 3.6.5.2; H-Ras-1; Ha-Ras; Transforming protein p21; c-H-ras; p21rasHomo sapiens (human)
Tyrosine-protein phosphatase non-receptor type 6EC 3.1.3.48; Hematopoietic cell protein-tyrosine phosphatase; Protein-tyrosine phosphatase 1C; PTP-1C; Protein-tyrosine phosphatase SHP-1; SH-PTP1Homo sapiens (human)
Signal transducer and activator of transcription 1-alpha/betaTranscription factor ISGF-3 components p91/p84Homo sapiens (human)
CREB-binding proteinHistone lysine acetyltransferase CREBBP; 2.3.1.48; Protein-lysine acetyltransferase CREBBP; 2.3.1.-Homo sapiens (human)
Mitogen-activated protein kinase kinase kinase kinase 1EC 2.7.11.1; Hematopoietic progenitor kinase; MAPK/ERK kinase kinase kinase 1; MEK kinase kinase 1; MEKKK 1Homo sapiens (human)
Proto-oncogene vavHomo sapiens (human)
Crk-like proteinHomo sapiens (human)
Microphthalmia-associated transcription factorClass E basic helix-loop-helix protein 32; bHLHe32Homo sapiens (human)
Suppressor of cytokine signaling 1SOCS-1; JAK-binding protein; JAB; STAT-induced STAT inhibitor 1; SSI-1; Tec-interacting protein 3; TIP-3Homo sapiens (human)
SH2B adapter protein 3Lymphocyte adapter protein; Lymphocyte-specific adapter protein Lnk; Signal transduction protein LnkHomo sapiens (human)
Zinc finger protein SNAI2Neural crest transcription factor Slug; Protein snail homolog 2Homo sapiens (human)
Sprouty-related, EVH1 domain-containing protein 1Spred-1; hSpred1Homo sapiens (human)
E3 ubiquitin-protein ligase CBLEC 2.3.2.27; Casitas B-lineage lymphoma proto-oncogene; Proto-oncogene c-Cbl; RING finger protein 55; RING-type E3 ubiquitin transferase CBL; Signal transduction protein CBLHomo sapiens (human)
GRB2-related adapter protein 2Adapter protein GRID; GRB-2-like protein; GRB2L; GRBLG; GRBX; Grf40 adapter protein; Grf-40; Growth factor receptor-binding protein; Hematopoietic cell-associated adapter protein GrpL; P38; Protein GADS; SH3-SH2-SH3 adapter MonaHomo sapiens (human)
Sprouty-related, EVH1 domain-containing protein 2Spred-2Homo sapiens (human)
Proline-rich transmembrane protein 2Dispanin subfamily B member 3; DSPB3Homo sapiens (human)
Docking protein 1Downstream of tyrosine kinase 1; p62(dok); pp62Homo sapiens (human)
Signal-transducing adaptor protein 1STAP-1; BCR downstream-signaling protein 1; Docking protein BRDG1; Stem cell adaptor protein 1Homo sapiens (human)

Compounds (0)

CompoundDescription