Page last updated: 2024-10-06

Signaling downstream of RAS mutants

Proteins (11)

ProteinSynonymsTaxonomy
RAF proto-oncogene serine/threonine-protein kinaseEC 2.7.11.1; Proto-oncogene c-RAF; cRaf; Raf-1Homo sapiens (human)
Serine/threonine-protein kinase B-rafEC 2.7.11.1; Proto-oncogene B-Raf; p94; v-Raf murine sarcoma viral oncogene homolog B1Homo sapiens (human)
MAP/microtubule affinity-regulating kinase 3EC 2.7.11.1; C-TAK1; cTAK1; Cdc25C-associated protein kinase 1; ELKL motif kinase 2; EMK-2; Protein kinase STK10; Ser/Thr protein kinase PAR-1; Par-1a; Serine/threonine-protein kinase p78Homo sapiens (human)
Dual specificity mitogen-activated protein kinase kinase 2MAP kinase kinase 2; MAPKK 2; EC 2.7.12.2; ERK activator kinase 2; MAPK/ERK kinase 2; MEK 2Homo sapiens (human)
Dual specificity mitogen-activated protein kinase kinase 1MAP kinase kinase 1; MAPKK 1; MKK1; EC 2.7.12.2; ERK activator kinase 1; MAPK/ERK kinase 1; MEK 1Homo sapiens (human)
Mitogen-activated protein kinase kinase kinase 11EC 2.7.11.25; Mixed lineage kinase 3; Src-homology 3 domain-containing proline-rich kinaseHomo sapiens (human)
Kinase suppressor of Ras 1EC 2.7.11.1Homo sapiens (human)
ProhibitinHomo sapiens (human)
Phosphatidylethanolamine-binding protein 1PEBP-1; HCNPpp; Neuropolypeptide h3; Prostatic-binding protein; Raf kinase inhibitor protein; RKIPHomo sapiens (human)
14-3-3 protein beta/alphaProtein 1054; Protein kinase C inhibitor protein 1; KCIP-1Homo sapiens (human)
BRCA1-associated proteinEC 2.3.2.27; BRAP2; Impedes mitogenic signal propagation; IMP; RING finger protein 52; RING-type E3 ubiquitin transferase BRAP2; Renal carcinoma antigen NY-REN-63Homo sapiens (human)

Compounds (3)

CompoundDescription
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
Guanosine MonophosphateA guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature.
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.