Page last updated: 2024-10-06
Signaling downstream of RAS mutants
Proteins (11)
| Protein | Synonyms | Taxonomy |
|---|---|---|
| RAF proto-oncogene serine/threonine-protein kinase | EC 2.7.11.1; Proto-oncogene c-RAF; cRaf; Raf-1 | Homo sapiens (human) |
| Serine/threonine-protein kinase B-raf | EC 2.7.11.1; Proto-oncogene B-Raf; p94; v-Raf murine sarcoma viral oncogene homolog B1 | Homo sapiens (human) |
| MAP/microtubule affinity-regulating kinase 3 | EC 2.7.11.1; C-TAK1; cTAK1; Cdc25C-associated protein kinase 1; ELKL motif kinase 2; EMK-2; Protein kinase STK10; Ser/Thr protein kinase PAR-1; Par-1a; Serine/threonine-protein kinase p78 | Homo sapiens (human) |
| Dual specificity mitogen-activated protein kinase kinase 2 | MAP kinase kinase 2; MAPKK 2; EC 2.7.12.2; ERK activator kinase 2; MAPK/ERK kinase 2; MEK 2 | Homo sapiens (human) |
| Dual specificity mitogen-activated protein kinase kinase 1 | MAP kinase kinase 1; MAPKK 1; MKK1; EC 2.7.12.2; ERK activator kinase 1; MAPK/ERK kinase 1; MEK 1 | Homo sapiens (human) |
| Mitogen-activated protein kinase kinase kinase 11 | EC 2.7.11.25; Mixed lineage kinase 3; Src-homology 3 domain-containing proline-rich kinase | Homo sapiens (human) |
| Kinase suppressor of Ras 1 | EC 2.7.11.1 | Homo sapiens (human) |
| Prohibitin | Homo sapiens (human) | |
| Phosphatidylethanolamine-binding protein 1 | PEBP-1; HCNPpp; Neuropolypeptide h3; Prostatic-binding protein; Raf kinase inhibitor protein; RKIP | Homo sapiens (human) |
| 14-3-3 protein beta/alpha | Protein 1054; Protein kinase C inhibitor protein 1; KCIP-1 | Homo sapiens (human) |
| BRCA1-associated protein | EC 2.3.2.27; BRAP2; Impedes mitogenic signal propagation; IMP; RING finger protein 52; RING-type E3 ubiquitin transferase BRAP2; Renal carcinoma antigen NY-REN-63 | Homo sapiens (human) |
Compounds (3)
| Compound | Description |
|---|---|
| adenosine diphosphate | Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position. |
| Guanosine Monophosphate | A guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature. |
| adenosine triphosphate | An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter. |