| Protein | Synonyms | Taxonomy |
|---|
| Transcription factor ETV6 | ETS translocation variant 6; ETS-related protein Tel1; Tel | Homo sapiens (human) |
| Vascular endothelial growth factor receptor 2 | VEGFR-2; EC 2.7.10.1; Fetal liver kinase 1; FLK-1; Kinase insert domain receptor; KDR; Protein-tyrosine kinase receptor flk-1 | Homo sapiens (human) |
| Platelet-derived growth factor receptor alpha | PDGF-R-alpha; PDGFR-alpha; EC 2.7.10.1; Alpha platelet-derived growth factor receptor; Alpha-type platelet-derived growth factor receptor; CD140 antigen-like family member A; CD140a antigen; Platelet-derived growth factor alpha receptor; Platelet-derived | Homo sapiens (human) |
| Son of sevenless homolog 1 | SOS-1 | Homo sapiens (human) |
| WD repeat-containing protein 48 | USP1-associated factor 1; WD repeat endosomal protein; p80 | Homo sapiens (human) |
| Striatin | | Homo sapiens (human) |
| Golgin subfamily A member 4 | 256 kDa golgin; Golgin-245; Protein 72.1; Trans-Golgi p230 | Homo sapiens (human) |
| KN motif and ankyrin repeat domain-containing protein 1 | Ankyrin repeat domain-containing protein 15; Kidney ankyrin repeat-containing protein | Homo sapiens (human) |
| Pre-mRNA 3'-end-processing factor FIP1 | hFip1; FIP1-like 1 protein; Factor interacting with PAP; Rearranged in hypereosinophilia | Homo sapiens (human) |
| Bridging integrator 2 | Breast cancer-associated protein 1 | Homo sapiens (human) |
| Compound | Description |
|---|
| regorafenib | has both antiangiogenic and antineoplastic activities; structure in first source |
| sorafenib | A niacinamide and phenylurea derivative that inhibits multiple intracellular and cell surface kinases thought to be involved in ANGIOGENESIS, including RAF KINASES and VEGF RECEPTORS. It is used in the treatment of advanced RENAL CELL CARCINOMA and HEPATOCELLULAR CARCINOMA, and for treatment of THYROID CARCINOMA refractory to radioactive iodine therapy. |
| adenosine diphosphate | Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position. |
| Guanosine Monophosphate | A guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature. |
| Guanosine Diphosphate | A guanine nucleotide containing two phosphate groups esterified to the sugar moiety. |
| adenosine triphosphate | An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter. |