Page last updated: 2024-10-06

Signaling by PDGF

Proteins (14)

ProteinSynonymsTaxonomy
Platelet-derived growth factor subunit BPDGF subunit B; PDGF-2; Platelet-derived growth factor B chain; Platelet-derived growth factor beta polypeptide; Proto-oncogene c-SisHomo sapiens (human)
Platelet-derived growth factor receptor betaPDGF-R-beta; PDGFR-beta; EC 2.7.10.1; Beta platelet-derived growth factor receptor; Beta-type platelet-derived growth factor receptor; CD140 antigen-like family member B; Platelet-derived growth factor receptor 1; PDGFR-1Homo sapiens (human)
Proto-oncogene tyrosine-protein kinase SrcEC 2.7.10.2; Proto-oncogene c-Src; pp60c-src; p60-SrcHomo sapiens (human)
Tyrosine-protein phosphatase non-receptor type 11EC 3.1.3.48; Protein-tyrosine phosphatase 1D; PTP-1D; Protein-tyrosine phosphatase 2C; PTP-2C; SH-PTP2; SHP-2; Shp2; SH-PTP3Homo sapiens (human)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1EC 3.1.4.11; PLC-148; Phosphoinositide phospholipase C-gamma-1; Phospholipase C-II; PLC-II; Phospholipase C-gamma-1; PLC-gamma-1Homo sapiens (human)
FurinEC 3.4.21.75; Dibasic-processing enzyme; Paired basic amino acid residue-cleaving enzyme; PACEHomo sapiens (human)
Platelet-derived growth factor receptor alphaPDGF-R-alpha; PDGFR-alpha; EC 2.7.10.1; Alpha platelet-derived growth factor receptor; Alpha-type platelet-derived growth factor receptor; CD140 antigen-like family member A; CD140a antigen; Platelet-derived growth factor alpha receptor; Platelet-derived Homo sapiens (human)
Growth factor receptor-bound protein 7B47; Epidermal growth factor receptor GRB-7; GRB7 adapter proteinHomo sapiens (human)
Son of sevenless homolog 1SOS-1Homo sapiens (human)
Rap guanine nucleotide exchange factor 1CRK SH3-binding GNRP; Guanine nucleotide-releasing factor 2; Protein C3GHomo sapiens (human)
Tyrosine-protein phosphatase non-receptor type 12EC 3.1.3.48; PTP-PEST; Protein-tyrosine phosphatase G1; PTPG1Homo sapiens (human)
Breast cancer anti-estrogen resistance protein 1CRK-associated substrate; Cas scaffolding protein family member 1; p130casHomo sapiens (human)
Ras GTPase-activating protein 1GAP; GTPase-activating protein; RasGAP; Ras p21 protein activator; p120GAPHomo sapiens (human)
Platelet-derived growth factor DPDGF-D; Iris-expressed growth factor; Spinal cord-derived growth factor B; SCDGF-BHomo sapiens (human)

Compounds (6)

CompoundDescription
Orthophosphate
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Guanosine MonophosphateA guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature.
Guanosine DiphosphateA guanine nucleotide containing two phosphate groups esterified to the sugar moiety.
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.