Page last updated: 2024-10-06

Signaling by NTRK1 (TRKA)

Proteins (63)

ProteinSynonymsTaxonomy
Myocyte-specific enhancer factor 2DHomo sapiens (human)
Serine/threonine-protein kinase Sgk1EC 2.7.11.1; Serum/glucocorticoid-regulated kinase 1Homo sapiens (human)
Ribosomal protein S6 kinase alpha-5S6K-alpha-5; EC 2.7.11.1; 90 kDa ribosomal protein S6 kinase 5; Nuclear mitogen- and stress-activated protein kinase 1; RSK-like protein kinase; RSKLHomo sapiens (human)
High affinity nerve growth factor receptorEC 2.7.10.1; Neurotrophic tyrosine kinase receptor type 1; TRK1-transforming tyrosine kinase protein; Tropomyosin-related kinase A; Tyrosine kinase receptor; Tyrosine kinase receptor A; Trk-A; gp140trk; p140-TrkAHomo sapiens (human)
Serine/threonine-protein kinase B-rafEC 2.7.11.1; Proto-oncogene B-Raf; p94; v-Raf murine sarcoma viral oncogene homolog B1Homo sapiens (human)
Mitogen-activated protein kinase 3 MAP kinase 3; MAPK 3; EC 2.7.11.24; ERT2; Extracellular signal-regulated kinase 1; ERK-1; Insulin-stimulated MAP2 kinase; MAP kinase isoform p44; p44-MAPK; Microtubule-associated protein 2 kinase; p44-ERK1Homo sapiens (human)
Mitogen-activated protein kinase 1MAP kinase 1; MAPK 1; EC 2.7.11.24; ERT1; Extracellular signal-regulated kinase 2; ERK-2; MAP kinase isoform p42; p42-MAPK; Mitogen-activated protein kinase 2; MAP kinase 2; MAPK 2Homo sapiens (human)
Adenosine receptor A2aHomo sapiens (human)
Dual specificity mitogen-activated protein kinase kinase 2MAP kinase kinase 2; MAPKK 2; EC 2.7.12.2; ERK activator kinase 2; MAPK/ERK kinase 2; MEK 2Homo sapiens (human)
MAP kinase-activated protein kinase 2MAPK-activated protein kinase 2; MAPKAP kinase 2; MAPKAP-K2; MAPKAPK-2; MK-2; MK2; EC 2.7.11.1Homo sapiens (human)
Cyclin-dependent-like kinase 5 EC 2.7.11.1; Cell division protein kinase 5; Serine/threonine-protein kinase PSSALRE; Tau protein kinase II catalytic subunit; TPKII catalytic subunitHomo sapiens (human)
Dual specificity mitogen-activated protein kinase kinase 1MAP kinase kinase 1; MAPKK 1; MKK1; EC 2.7.12.2; ERK activator kinase 1; MAPK/ERK kinase 1; MEK 1Homo sapiens (human)
Tribbles homolog 1TRB-1; G-protein-coupled receptor-induced gene 2 protein; GIG-2; SKIP1Homo sapiens (human)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1EC 3.1.4.11; PLC-148; Phosphoinositide phospholipase C-gamma-1; Phospholipase C-II; PLC-II; Phospholipase C-gamma-1; PLC-gamma-1Homo sapiens (human)
Signal transducer and activator of transcription 3Acute-phase response factorHomo sapiens (human)
Histone acetyltransferase p300p300 HAT; EC 2.3.1.48; E1A-associated protein p300; Histone butyryltransferase p300; 2.3.1.-; Histone crotonyltransferase p300; 2.3.1.-; Protein 2-hydroxyisobutyryltransferase p300; 2.3.1.-; Protein propionyltransferase p300; 2.3.1.-Homo sapiens (human)
Dual specificity mitogen-activated protein kinase kinase 5MAP kinase kinase 5; MAPKK 5; EC 2.7.12.2; MAPK/ERK kinase 5; MEK 5Homo sapiens (human)
Mitogen-activated protein kinase 7MAP kinase 7; MAPK 7; EC 2.7.11.24; Big MAP kinase 1; BMK-1; Extracellular signal-regulated kinase 5; ERK-5Homo sapiens (human)
Cyclin-dependent kinase 5 activator 1CDK5 activator 1; Cyclin-dependent kinase 5 regulatory subunit 1; TPKII regulatory subunitHomo sapiens (human)
Early growth response protein 1EGR-1; AT225; Nerve growth factor-induced protein A; NGFI-A; Transcription factor ETR103; Transcription factor Zif268; Zinc finger protein 225; Zinc finger protein Krox-24Homo sapiens (human)
Chromodomain-helicase-DNA-binding protein 4CHD-4; EC 3.6.4.12; ATP-dependent helicase CHD4; Mi-2 autoantigen 218 kDa protein; Mi2-betaHomo sapiens (human)
Cyclic AMP-dependent transcription factor ATF-1cAMP-dependent transcription factor ATF-1; Activating transcription factor 1; Protein TREB36Homo sapiens (human)
Cyclic AMP-responsive element-binding protein 1CREB-1; cAMP-responsive element-binding protein 1Homo sapiens (human)
Tryptophan 5-hydroxylase 1EC 1.14.16.4; Tryptophan 5-monooxygenase 1Homo sapiens (human)
Pituitary adenylate cyclase-activating polypeptide type I receptorPACAP type I receptor; PACAP-R-1; PACAP-R1Homo sapiens (human)
Adapter molecule crkProto-oncogene c-Crk; p38Homo sapiens (human)
Dynamin-2EC 3.6.5.5Homo sapiens (human)
Beta-nerve growth factorBeta-NGFHomo sapiens (human)
Son of sevenless homolog 1SOS-1Homo sapiens (human)
Serum response factorSRFHomo sapiens (human)
Rap guanine nucleotide exchange factor 1CRK SH3-binding GNRP; Guanine nucleotide-releasing factor 2; Protein C3GHomo sapiens (human)
Tissue factorTF; Coagulation factor III; ThromboplastinHomo sapiens (human)
Dual specificity protein phosphatase 3EC 3.1.3.16; EC 3.1.3.48; Dual specificity protein phosphatase VHR; Vaccinia H1-related phosphatase; VHRHomo sapiens (human)
Transforming protein RhoAEC 3.6.5.2; Rho cDNA clone 12; h12Homo sapiens (human)
Ras-related protein Rap-1AEC 3.6.5.2; C21KG; G-22K; GTP-binding protein smg p21A; Ras-related protein Krev-1Homo sapiens (human)
Clathrin heavy chain 1Clathrin heavy chain on chromosome 17; CLH-17Homo sapiens (human)
Ras-related protein Ral-BEC 3.6.5.2Homo sapiens (human)
14-3-3 protein beta/alphaProtein 1054; Protein kinase C inhibitor protein 1; KCIP-1Homo sapiens (human)
ETS domain-containing protein Elk-1Homo sapiens (human)
Clathrin light chain ALcaHomo sapiens (human)
Ras-related protein Ral-AEC 3.6.5.2Homo sapiens (human)
Crk-like proteinHomo sapiens (human)
NGFI-A-binding protein 2EGR-1-binding protein 2; Melanoma-associated delayed early response protein; Protein MADERHomo sapiens (human)
Inactive serine/threonine-protein kinase VRK3Serine/threonine-protein pseudokinase VRK3; Vaccinia-related kinase 3Homo sapiens (human)
RE1-silencing transcription factorNeural-restrictive silencer factor; X2 box repressorHomo sapiens (human)
Kinase D-interacting substrate of 220 kDaAnkyrin repeat-rich membrane-spanning proteinHomo sapiens (human)
AP-2 complex subunit sigmaAdaptor protein complex AP-2 subunit sigma; Adaptor-related protein complex 2 subunit sigma; Clathrin assembly protein 2 sigma small chain; Clathrin coat assembly protein AP17; Clathrin coat-associated protein AP17; HA2 17 kDa subunit; Plasma membrane adaHomo sapiens (human)
E3 SUMO-protein ligase EGR2EC 2.3.2.-; AT591; E3 SUMO-protein transferase ERG2; Early growth response protein 2; EGR-2; Zinc finger protein Krox-20Homo sapiens (human)
GTP-binding protein RADRAD1; Ras associated with diabetesHomo sapiens (human)
Ral guanine nucleotide dissociation stimulatorRalGDS; Ral guanine nucleotide exchange factor; RalGEFHomo sapiens (human)
Neurosecretory protein VGFHomo sapiens (human)
Achaete-scute homolog 1ASH-1; hASH1; Class A basic helix-loop-helix protein 46; bHLHa46Homo sapiens (human)
Dynein light chain 4, axonemalHomo sapiens (human)
Protein lyl-1Class A basic helix-loop-helix protein 18; bHLHa18; Lymphoblastic leukemia-derived sequence 1Homo sapiens (human)
Pituitary adenylate cyclase-activating polypeptidePACAPHomo sapiens (human)
AP-2 complex subunit betaAP105B; Adaptor protein complex AP-2 subunit beta; Adaptor-related protein complex 2 subunit beta; Beta-2-adaptin; Beta-adaptin; Clathrin assembly protein complex 2 beta large chain; Plasma membrane adaptor HA2/AP2 adaptin beta subunitHomo sapiens (human)
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoformPP2A B subunit isoform B'-delta; PP2A B subunit isoform B56-delta; PP2A B subunit isoform PR61-delta; PP2A B subunit isoform R5-deltaHomo sapiens (human)
Activity-regulated cytoskeleton-associated proteinhArc; Activity-regulated gene 3.1 protein homolog; ARC/ARG3.1; Arg3.1Homo sapiens (human)
Fibroblast growth factor receptor substrate 2FGFR substrate 2; FGFR-signaling adaptor SNT; Suc1-associated neurotrophic factor target 1; SNT-1Homo sapiens (human)
AP-2 complex subunit muAP-2 mu chain; Adaptin-mu2; Adaptor protein complex AP-2 subunit mu; Adaptor-related protein complex 2 subunit mu; Clathrin assembly protein complex 2 mu medium chain; Clathrin coat assembly protein AP50; Clathrin coat-associated protein AP50; HA2 50 kDa Homo sapiens (human)
Transcription factor 12TCF-12; Class B basic helix-loop-helix protein 20; bHLHb20; DNA-binding protein HTF4; E-box-binding protein; Transcription factor HTF-4Homo sapiens (human)
Endophilin-A1EEN-B1; Endophilin-1; SH3 domain protein 2A; SH3 domain-containing GRB2-like protein 2Homo sapiens (human)
Endophilin-A3EEN-B2; Endophilin-3; SH3 domain protein 2C; SH3 domain-containing GRB2-like protein 3Homo sapiens (human)

Compounds (9)

CompoundDescription
ZincA metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn.
Orthophosphate
adenosineA nucleoside that is composed of ADENINE and D-RIBOSE. Adenosine or adenosine derivatives play many important biological roles in addition to being components of DNA and RNA. Adenosine itself is a neurotransmitter.
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
MagnesiumA metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Guanosine MonophosphateA guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature.
Guanosine DiphosphateA guanine nucleotide containing two phosphate groups esterified to the sugar moiety.
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.