Page last updated: 2024-10-06

Signaling by NOTCH1

Proteins (26)

ProteinSynonymsTaxonomy
E3 ubiquitin-protein ligase RBX1EC 2.3.2.27; EC 2.3.2.32; E3 ubiquitin-protein transferase RBX1; Protein ZYP; RING finger protein 75; RING-box protein 1; Rbx1; Regulator of cullins 1; ROC1Homo sapiens (human)
Recombining binding protein suppressor of hairlessCBF-1; J kappa-recombination signal-binding protein; RBP-J kappa; RBP-J; RBP-JK; Renal carcinoma antigen NY-REN-30Homo sapiens (human)
Hypoxia-inducible factor 1-alphaHIF-1-alpha; HIF1-alpha; ARNT-interacting protein; Basic-helix-loop-helix-PAS protein MOP1; Class E basic helix-loop-helix protein 78; bHLHe78; Member of PAS protein 1; PAS domain-containing protein 8Homo sapiens (human)
NicastrinHomo sapiens (human)
Protein delta homolog 1DLK-1; pG2Homo sapiens (human)
Histone acetyltransferase p300p300 HAT; EC 2.3.1.48; E1A-associated protein p300; Histone butyryltransferase p300; 2.3.1.-; Histone crotonyltransferase p300; 2.3.1.-; Protein 2-hydroxyisobutyryltransferase p300; 2.3.1.-; Protein propionyltransferase p300; 2.3.1.-Homo sapiens (human)
Gamma-secretase subunit PEN-2Presenilin enhancer protein 2Homo sapiens (human)
Cullin-1CUL-1Homo sapiens (human)
E3 ubiquitin-protein ligase Itchy homologItch; EC 2.3.2.26; Atrophin-1-interacting protein 4; AIP4; HECT-type E3 ubiquitin transferase Itchy homolog; NFE2-associated polypeptide 1; NAPP1Homo sapiens (human)
Cyclin-CSRB11 homolog; hSRB11Homo sapiens (human)
Protein jagged-2Jagged2; hJ2Homo sapiens (human)
Myc proto-oncogene proteinClass E basic helix-loop-helix protein 39; bHLHe39; Proto-oncogene c-Myc; Transcription factor p64Homo sapiens (human)
Cyclin-dependent kinase 8EC 2.7.11.22; EC 2.7.11.23; Cell division protein kinase 8; Mediator complex subunit CDK8; Mediator of RNA polymerase II transcription subunit CDK8; Protein kinase K35Homo sapiens (human)
CREB-binding proteinHistone lysine acetyltransferase CREBBP; 2.3.1.48; Protein-lysine acetyltransferase CREBBP; 2.3.1.-Homo sapiens (human)
Protein jagged-1Jagged1; hJ1Homo sapiens (human)
Neurogenic locus notch homolog protein 1Notch 1; hN1; Translocation-associated notch protein TAN-1Homo sapiens (human)
S-phase kinase-associated protein 1Cyclin-A/CDK2-associated protein p19; p19A; Organ of Corti protein 2; OCP-2; Organ of Corti protein II; OCP-II; RNA polymerase II elongation factor-like protein; SIII; Transcription elongation factor B polypeptide 1-like; p19skp1Homo sapiens (human)
Transcription factor HES-1Class B basic helix-loop-helix protein 39; bHLHb39; Hairy and enhancer of split 1; Hairy homolog; Hairy-like protein; hHLHomo sapiens (human)
Delta and Notch-like epidermal growth factor-related receptorHomo sapiens (human)
Protein numb homologh-Numb; Protein S171Homo sapiens (human)
Delta-like protein 1Drosophila Delta homolog 1; Delta1; H-Delta-1Homo sapiens (human)
Contactin-1Glycoprotein gp135; Neural cell surface protein F3Homo sapiens (human)
SNW domain-containing protein 1Nuclear protein SkiP; Nuclear receptor coactivator NCoA-62; Ski-interacting proteinHomo sapiens (human)
Transcription factor HES-5Class B basic helix-loop-helix protein 38; bHLHb38; Hairy and enhancer of split 5Homo sapiens (human)
NeurobeachinLysosomal-trafficking regulator 2; Protein BCL8BHomo sapiens (human)
Delta-like protein 4Drosophila Delta homolog 4; Delta4Homo sapiens (human)

Compounds (3)

CompoundDescription
ZincA metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn.
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.