Pathways > Signaling by Insulin receptor
Page last updated: 2024-10-06
Signaling by Insulin receptor
Proteins (15)
| Protein | Synonyms | Taxonomy |
|---|
| 3-phosphoinositide-dependent protein kinase 1 | hPDK1; EC 2.7.11.1 | Homo sapiens (human) |
| Insulin receptor | IR; EC 2.7.10.1 | Homo sapiens (human) |
| RAC-beta serine/threonine-protein kinase | EC 2.7.11.1; Protein kinase Akt-2; Protein kinase B beta; PKB beta; RAC-PK-beta | Homo sapiens (human) |
| Cathepsin D | EC 3.4.23.5 | Homo sapiens (human) |
| Phosphatidylinositol 3-kinase regulatory subunit alpha | PI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; PI3-kinase subunit p85-alpha; PtdIns-3-kinase regulatory subunit p85-alpha | Homo sapiens (human) |
| SHC-transforming protein 1 | SHC-transforming protein 3; SHC-transforming protein A; Src homology 2 domain-containing-transforming protein C1; SH2 domain protein C1 | Homo sapiens (human) |
| cGMP-inhibited 3',5'-cyclic phosphodiesterase B | EC 3.1.4.17; CGIPDE1; CGIP1; Cyclic GMP-inhibited phosphodiesterase B; CGI-PDE B | Homo sapiens (human) |
| Growth factor receptor-bound protein 10 | GRB10 adapter protein; Insulin receptor-binding protein Grb-IR | Homo sapiens (human) |
| Insulin | | Homo sapiens (human) |
| Son of sevenless homolog 1 | SOS-1 | Homo sapiens (human) |
| V-type proton ATPase subunit S1 | V-ATPase subunit S1; Protein XAP-3; V-ATPase Ac45 subunit; V-ATPase S1 accessory protein; Vacuolar proton pump subunit S1 | Homo sapiens (human) |
| V-type proton ATPase subunit F | V-ATPase subunit F; V-ATPase 14 kDa subunit; Vacuolar proton pump subunit F | Homo sapiens (human) |
| V-type proton ATPase 21 kDa proteolipid subunit | V-ATPase 21 kDa proteolipid subunit; Vacuolar proton pump 21 kDa proteolipid subunit; hATPL | Homo sapiens (human) |
| V-type proton ATPase subunit H | V-ATPase subunit H; Nef-binding protein 1; NBP1; Protein VMA13 homolog; V-ATPase 50/57 kDa subunits; Vacuolar proton pump subunit H; Vacuolar proton pump subunit SFD | Homo sapiens (human) |
| V-type proton ATPase subunit D | V-ATPase subunit D; V-ATPase 28 kDa accessory protein; Vacuolar proton pump subunit D | Homo sapiens (human) |
Compounds (9)
| Compound | Description |
|---|
| hydronium ion | |
| Orthophosphate | |
| adenosine diphosphate | Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position. |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| Guanosine Monophosphate | A guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature. |
| Guanosine Diphosphate | A guanine nucleotide containing two phosphate groups esterified to the sugar moiety. |
| adenosine monophosphate | Adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position. |
| adenosine triphosphate | An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter. |
| cyclic amp | An adenine nucleotide containing one phosphate group which is esterified to both the 3'- and 5'-positions of the sugar moiety. It is a second messenger and a key intracellular regulator, functioning as a mediator of activity for a number of hormones, including epinephrine, glucagon, and ACTH. |