Page last updated: 2024-10-06

Signaling by FGFR in disease

Proteins (24)

ProteinSynonymsTaxonomy
Fibroblast growth factor receptor 1FGFR-1; EC 2.7.10.1; Basic fibroblast growth factor receptor 1; BFGFR; bFGF-R-1; Fms-like tyrosine kinase 2; FLT-2; N-sam; Proto-oncogene c-FgrHomo sapiens (human)
Fibroblast growth factor receptor 3FGFR-3; EC 2.7.10.1Homo sapiens (human)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformPI3-kinase subunit alpha; PI3K-alpha; PI3Kalpha; PtdIns-3-kinase subunit alpha; EC 2.7.1.137; EC 2.7.1.153; Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha; PtdIns-3-kinase subunit p110-alpha; p110alpha; Phosphoinositide 3-kHomo sapiens (human)
Centrosomal protein 43FGFR1 oncogene partnerHomo sapiens (human)
Erlin-2Endoplasmic reticulum lipid raft-associated protein 2; Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2; SPFH domain-containing protein 2Homo sapiens (human)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1EC 3.1.4.11; PLC-148; Phosphoinositide phospholipase C-gamma-1; Phospholipase C-II; PLC-II; Phospholipase C-gamma-1; PLC-gamma-1Homo sapiens (human)
Fibroblast growth factor receptor 2FGFR-2; EC 2.7.10.1; K-sam; KGFR; Keratinocyte growth factor receptorHomo sapiens (human)
Fibroblast growth factor receptor 4FGFR-4; EC 2.7.10.1Homo sapiens (human)
Phosphatidylinositol 3-kinase regulatory subunit alphaPI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; PI3-kinase subunit p85-alpha; PtdIns-3-kinase regulatory subunit p85-alphaHomo sapiens (human)
Son of sevenless homolog 1SOS-1Homo sapiens (human)
GRB2-associated-binding protein 1GRB2-associated binder 1; Growth factor receptor bound protein 2-associated protein 1Homo sapiens (human)
Breakpoint cluster region proteinEC 2.7.11.1; Renal carcinoma antigen NY-REN-26Homo sapiens (human)
Leucine-rich repeat flightless-interacting protein 1LRR FLII-interacting protein 1; GC-binding factor 2; TAR RNA-interacting proteinHomo sapiens (human)
Homeobox protein cut-like 1CCAAT displacement protein; CDP; CDP/Cux p200; Homeobox protein cux-1Homo sapiens (human)
Transcription intermediary factor 1-alphaTIF1-alpha; EC 2.3.2.27; E3 ubiquitin-protein ligase TRIM24; RING finger protein 82; RING-type E3 ubiquitin transferase TIF1-alpha; Tripartite motif-containing protein 24Homo sapiens (human)
Cleavage and polyadenylation specificity factor subunit 6Cleavage and polyadenylation specificity factor 68 kDa subunit; CPSF 68 kDa subunit; Cleavage factor Im complex 68 kDa subunit; CFIm68; Pre-mRNA cleavage factor Im 68 kDa subunit; Protein HPBRII-4/7Homo sapiens (human)
Nuclear cap-binding protein subunit 220 kDa nuclear cap-binding protein; Cell proliferation-inducing gene 55 protein; NCBP 20 kDa subunit; CBP20; NCBP-interacting protein 1; NIP1Homo sapiens (human)
GRB2-associated-binding protein 2GRB2-associated binder 2; Growth factor receptor bound protein 2-associated protein 2; pp100Homo sapiens (human)
BAG family molecular chaperone regulator 4BAG-4; Bcl-2-associated athanogene 4; Silencer of death domainsHomo sapiens (human)
Nuclear cap-binding protein subunit 180 kDa nuclear cap-binding protein; CBP80; NCBP 80 kDa subunitHomo sapiens (human)
Fibroblast growth factor receptor substrate 2FGFR substrate 2; FGFR-signaling adaptor SNT; Suc1-associated neurotrophic factor target 1; SNT-1Homo sapiens (human)
Unconventional myosin-XVIIIaMolecule associated with JAK3 N-terminus; MAJN; Myosin containing a PDZ domain; Surfactant protein receptor SP-R210; SP-R210Homo sapiens (human)
FGFR1 oncogene partner 2Homo sapiens (human)
Zinc finger MYM-type protein 2Fused in myeloproliferative disorders protein; Rearranged in atypical myeloproliferative disorder protein; Zinc finger protein 198Homo sapiens (human)

Compounds (5)

CompoundDescription
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
Guanosine MonophosphateA guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature.
Guanosine DiphosphateA guanine nucleotide containing two phosphate groups esterified to the sugar moiety.
pd 173074has antineoplastic activity; a protein kinase inhibitor and angiogenesis inhibitor; structure in first source
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.