Page last updated: 2024-10-06

Signaling by CSF1 (M-CSF) in myeloid cells

Proteins (23)

ProteinSynonymsTaxonomy
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2EC 3.1.3.86; Inositol polyphosphate phosphatase-like protein 1; INPPL-1; Protein 51C; SH2 domain-containing inositol 5'-phosphatase 2; SH2 domain-containing inositol phosphatase 2; SHIP-2Homo sapiens (human)
Tyrosine-protein kinase FynEC 2.7.10.2; Proto-oncogene Syn; Proto-oncogene c-Fyn; Src-like kinase; SLK; p59-FynHomo sapiens (human)
Tyrosine-protein kinase LynEC 2.7.10.2; Lck/Yes-related novel protein tyrosine kinase; V-yes-1 Yamaguchi sarcoma viral related oncogene homolog; p53Lyn; p56LynHomo sapiens (human)
Proto-oncogene tyrosine-protein kinase SrcEC 2.7.10.2; Proto-oncogene c-Src; pp60c-src; p60-SrcHomo sapiens (human)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformPI3-kinase subunit alpha; PI3K-alpha; PI3Kalpha; PtdIns-3-kinase subunit alpha; EC 2.7.1.137; EC 2.7.1.153; Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha; PtdIns-3-kinase subunit p110-alpha; p110alpha; Phosphoinositide 3-kHomo sapiens (human)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform PI3-kinase subunit gamma; PI3K-gamma; PI3Kgamma; PtdIns-3-kinase subunit gamma; EC 2.7.1.137; EC 2.7.1.153; EC 2.7.1.154; Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma; PtdIns-3-kinase subunit p110-gamma; p110gamma; PhosphHomo sapiens (human)
Tyrosine-protein phosphatase non-receptor type 11EC 3.1.3.48; Protein-tyrosine phosphatase 1D; PTP-1D; Protein-tyrosine phosphatase 2C; PTP-2C; SH-PTP2; SHP-2; Shp2; SH-PTP3Homo sapiens (human)
Macrophage colony-stimulating factor 1 receptorCSF-1 receptor; CSF-1-R; CSF-1R; M-CSF-R; 2.7.10.1; Proto-oncogene c-FmsHomo sapiens (human)
Tyrosine-protein kinase YesEC 2.7.10.2; Proto-oncogene c-Yes; p61-YesHomo sapiens (human)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2EC 3.1.4.11; Phosphoinositide phospholipase C-gamma-2; Phospholipase C-IV; PLC-IV; Phospholipase C-gamma-2; PLC-gamma-2Homo sapiens (human)
Phosphatidylinositol 3-kinase regulatory subunit alphaPI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; PI3-kinase subunit p85-alpha; PtdIns-3-kinase regulatory subunit p85-alphaHomo sapiens (human)
SHC-transforming protein 1SHC-transforming protein 3; SHC-transforming protein A; Src homology 2 domain-containing-transforming protein C1; SH2 domain protein C1Homo sapiens (human)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoformPI3-kinase subunit beta; PI3K-beta; PI3Kbeta; PtdIns-3-kinase subunit beta; EC 2.7.1.153; Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta; PtdIns-3-kinase subunit p110-beta; p110betaHomo sapiens (human)
Son of sevenless homolog 1SOS-1Homo sapiens (human)
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 EC 3.1.3.86; Inositol polyphosphate-5-phosphatase D; 3.1.3.56; Inositol polyphosphate-5-phosphatase of 145 kDa; SIP-145; Phosphatidylinositol 4,5-bisphosphate 5-phosphatase; 3.1.3.36; SH2 domain-containing inositol 5'-phosphatase 1; SH2 domain-containing Homo sapiens (human)
GTPase KRasEC 3.6.5.2; K-Ras 2; Ki-Ras; c-K-ras; c-Ki-rasHomo sapiens (human)
Macrophage colony-stimulating factor 1CSF-1; M-CSF; MCSF; LanimostimHomo sapiens (human)
GRB2-associated-binding protein 2GRB2-associated binder 2; Growth factor receptor bound protein 2-associated protein 2; pp100Homo sapiens (human)
E3 ubiquitin-protein ligase CBLEC 2.3.2.27; Casitas B-lineage lymphoma proto-oncogene; Proto-oncogene c-Cbl; RING finger protein 55; RING-type E3 ubiquitin transferase CBL; Signal transduction protein CBLHomo sapiens (human)
GRB2-related adapter protein 2Adapter protein GRID; GRB-2-like protein; GRB2L; GRBLG; GRBX; Grf40 adapter protein; Grf-40; Growth factor receptor-binding protein; Hematopoietic cell-associated adapter protein GrpL; P38; Protein GADS; SH3-SH2-SH3 adapter MonaHomo sapiens (human)
THO complex subunit 5 homologFunctional spliceosome-associated protein 79; fSAP79; NF2/meningioma region protein pK1.3; Placental protein 39.2; PP39.2; hTREX90Homo sapiens (human)
Interleukin-34IL-34Homo sapiens (human)
GRB2-associated-binding protein 3GRB2-associated binder 3; Growth factor receptor bound protein 2-associated protein 3Homo sapiens (human)

Compounds (6)

CompoundDescription
phosphorylcholineCalcium and magnesium salts used therapeutically in hepatobiliary dysfunction.
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Guanosine MonophosphateA guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature.
Guanosine DiphosphateA guanine nucleotide containing two phosphate groups esterified to the sugar moiety.
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.