Signaling by CSF1 (M-CSF) in myeloid cells

Proteins (23)

Protein	Synonyms	Taxonomy
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2	EC 3.1.3.86; Inositol polyphosphate phosphatase-like protein 1; INPPL-1; Protein 51C; SH2 domain-containing inositol 5'-phosphatase 2; SH2 domain-containing inositol phosphatase 2; SHIP-2	Homo sapiens (human)
Tyrosine-protein kinase Fyn	EC 2.7.10.2; Proto-oncogene Syn; Proto-oncogene c-Fyn; Src-like kinase; SLK; p59-Fyn	Homo sapiens (human)
Tyrosine-protein kinase Lyn	EC 2.7.10.2; Lck/Yes-related novel protein tyrosine kinase; V-yes-1 Yamaguchi sarcoma viral related oncogene homolog; p53Lyn; p56Lyn	Homo sapiens (human)
Proto-oncogene tyrosine-protein kinase Src	EC 2.7.10.2; Proto-oncogene c-Src; pp60c-src; p60-Src	Homo sapiens (human)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	PI3-kinase subunit alpha; PI3K-alpha; PI3Kalpha; PtdIns-3-kinase subunit alpha; EC 2.7.1.137; EC 2.7.1.153; Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha; PtdIns-3-kinase subunit p110-alpha; p110alpha; Phosphoinositide 3-k	Homo sapiens (human)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	PI3-kinase subunit gamma; PI3K-gamma; PI3Kgamma; PtdIns-3-kinase subunit gamma; EC 2.7.1.137; EC 2.7.1.153; EC 2.7.1.154; Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma; PtdIns-3-kinase subunit p110-gamma; p110gamma; Phosph	Homo sapiens (human)
Tyrosine-protein phosphatase non-receptor type 11	EC 3.1.3.48; Protein-tyrosine phosphatase 1D; PTP-1D; Protein-tyrosine phosphatase 2C; PTP-2C; SH-PTP2; SHP-2; Shp2; SH-PTP3	Homo sapiens (human)
Macrophage colony-stimulating factor 1 receptor	CSF-1 receptor; CSF-1-R; CSF-1R; M-CSF-R; 2.7.10.1; Proto-oncogene c-Fms	Homo sapiens (human)
Tyrosine-protein kinase Yes	EC 2.7.10.2; Proto-oncogene c-Yes; p61-Yes	Homo sapiens (human)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2	EC 3.1.4.11; Phosphoinositide phospholipase C-gamma-2; Phospholipase C-IV; PLC-IV; Phospholipase C-gamma-2; PLC-gamma-2	Homo sapiens (human)
Phosphatidylinositol 3-kinase regulatory subunit alpha	PI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; PI3-kinase subunit p85-alpha; PtdIns-3-kinase regulatory subunit p85-alpha	Homo sapiens (human)
SHC-transforming protein 1	SHC-transforming protein 3; SHC-transforming protein A; Src homology 2 domain-containing-transforming protein C1; SH2 domain protein C1	Homo sapiens (human)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	PI3-kinase subunit beta; PI3K-beta; PI3Kbeta; PtdIns-3-kinase subunit beta; EC 2.7.1.153; Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta; PtdIns-3-kinase subunit p110-beta; p110beta	Homo sapiens (human)
Son of sevenless homolog 1	SOS-1	Homo sapiens (human)
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1	EC 3.1.3.86; Inositol polyphosphate-5-phosphatase D; 3.1.3.56; Inositol polyphosphate-5-phosphatase of 145 kDa; SIP-145; Phosphatidylinositol 4,5-bisphosphate 5-phosphatase; 3.1.3.36; SH2 domain-containing inositol 5'-phosphatase 1; SH2 domain-containing	Homo sapiens (human)
GTPase KRas	EC 3.6.5.2; K-Ras 2; Ki-Ras; c-K-ras; c-Ki-ras	Homo sapiens (human)
Macrophage colony-stimulating factor 1	CSF-1; M-CSF; MCSF; Lanimostim	Homo sapiens (human)
GRB2-associated-binding protein 2	GRB2-associated binder 2; Growth factor receptor bound protein 2-associated protein 2; pp100	Homo sapiens (human)
E3 ubiquitin-protein ligase CBL	EC 2.3.2.27; Casitas B-lineage lymphoma proto-oncogene; Proto-oncogene c-Cbl; RING finger protein 55; RING-type E3 ubiquitin transferase CBL; Signal transduction protein CBL	Homo sapiens (human)
GRB2-related adapter protein 2	Adapter protein GRID; GRB-2-like protein; GRB2L; GRBLG; GRBX; Grf40 adapter protein; Grf-40; Growth factor receptor-binding protein; Hematopoietic cell-associated adapter protein GrpL; P38; Protein GADS; SH3-SH2-SH3 adapter Mona	Homo sapiens (human)
THO complex subunit 5 homolog	Functional spliceosome-associated protein 79; fSAP79; NF2/meningioma region protein pK1.3; Placental protein 39.2; PP39.2; hTREX90	Homo sapiens (human)
Interleukin-34	IL-34	Homo sapiens (human)
GRB2-associated-binding protein 3	GRB2-associated binder 3; Growth factor receptor bound protein 2-associated protein 3	Homo sapiens (human)

Compounds (6)

Compound	Description
phosphorylcholine	Calcium and magnesium salts used therapeutically in hepatobiliary dysfunction.
adenosine diphosphate	Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
Water	A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Guanosine Monophosphate	A guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature.
Guanosine Diphosphate	A guanine nucleotide containing two phosphate groups esterified to the sugar moiety.
adenosine triphosphate	An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.