Sensing of DNA Double Strand Breaks

Proteins (6)

Protein	Synonyms	Taxonomy
Nibrin	Cell cycle regulatory protein p95; Nijmegen breakage syndrome protein 1	Homo sapiens (human)
Double-strand break repair protein MRE11	EC 3.1.-.-; Double-strand break repair protein MRE11A; Meiotic recombination 11 homolog 1; MRE11 homolog 1; Meiotic recombination 11 homolog A; MRE11 homolog A	Homo sapiens (human)
Serine-protein kinase ATM	EC 2.7.11.1; Ataxia telangiectasia mutated; A-T mutated	Homo sapiens (human)
Histone acetyltransferase KAT5	EC 2.3.1.48; 60 kDa Tat-interactive protein; Tip60; Histone acetyltransferase HTATIP; HIV-1 Tat interactive protein; Lysine acetyltransferase 5; cPLA(2)-interacting protein	Homo sapiens (human)
Importin subunit alpha-1	Karyopherin subunit alpha-2; RAG cohort protein 1; SRP1-alpha	Homo sapiens (human)
DNA repair protein RAD50	hRAD50; EC 3.6.-.-	Homo sapiens (human)

Compound	Description
adenosine diphosphate	Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
adenosine triphosphate	An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
Coenzyme A
Acetyl Coenzyme A	Acetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.