Page last updated: 2024-10-06

Secondary Metabolites: Ubiquinol Biosynthesis

Proteins (9)

ProteinSynonymsTaxonomy
Octaprenyl diphosphate synthaseEC 2.5.1.90; All-trans-octaprenyl-diphosphate synthase; Octaprenyl pyrophosphate synthase; OPP synthaseEscherichia coli K-12
Chorismate pyruvate-lyaseCL; CPL; EC 4.1.3.40Escherichia coli K-12
3-octaprenyl-4-hydroxybenzoate carboxy-lyaseEC 4.1.1.98; Polyprenyl p-hydroxybenzoate decarboxylaseEscherichia coli K-12
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiEEC 2.1.1.163; EC 2.1.1.201; 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase; Demethylmenaquinone methyltransferaseEscherichia coli K-12
4-hydroxybenzoate octaprenyltransferaseEC 2.5.1.39; 4-HB polyprenyltransferase; PHB octaprenyl transferaseEscherichia coli K-12
Ubiquinone biosynthesis O-methyltransferase2-octaprenyl-6-hydroxyphenol methylase; 2.1.1.222; 3-demethylubiquinone-8 3-O-methyltransferase; 2.1.1.64Escherichia coli K-12
2-octaprenyl-6-methoxyphenol hydroxylaseEC 1.14.13.-Escherichia coli K-12
2-octaprenylphenol hydroxylaseEC 1.14.13.240; 2-polyprenylphenol 6-hydroxylaseEscherichia coli K-12
3-demethoxyubiquinol 3-hydroxylaseEC 1.14.99.60; 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylaseEscherichia coli K-12

Compounds (13)

CompoundDescription
hydronium ion
pyruvic acidAn intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
OxygenAn element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
isopentenyl pyrophosphatesubstrate for isopentenyl pyrophosphate isomerase; RN given refers to unlabeled cpd; a nonpeptide mycobacterial antigen that stimulates gamma delta T cells
chorismic acidA cyclohexadiene carboxylic acid derived from SHIKIMIC ACID and a precursor for the biosynthesis of UBIQUINONE and the AROMATIC AMINO ACIDS.
4-hydroxybenzoic acid
farnesyl pyrophosphatea sesquiterpene that dimerizes to SQUALENE; RN given refers to cpd without isomeric designation
2-octaprenyl phenolbiosynthetic precursor of ubiquinone-8
s-adenosylmethioninePhysiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed)
creolinfrom refined coal tar oils
pyrophosphate