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Secondary Metabolites: Threonine Biosynthesis from Aspartate

Proteins (7)

ProteinSynonymsTaxonomy
Bifunctional aspartokinase/homoserine dehydrogenase 1Aspartokinase I/homoserine dehydrogenase I; AKI-HDIEscherichia coli K-12
Homoserine kinaseHK; HSK; EC 2.7.1.39Escherichia coli K-12
4-hydroxy-tetrahydrodipicolinate synthaseHTPA synthase; EC 4.3.3.7Escherichia coli K-12
Lysine-sensitive aspartokinase 3EC 2.7.2.4; Aspartate kinase III; AKIII; Lysine-sensitive aspartokinase IIIEscherichia coli K-12
Threonine synthaseTS; EC 4.2.3.1Escherichia coli K-12
Bifunctional aspartokinase/homoserine dehydrogenase 2Aspartokinase II/homoserine dehydrogenase II; AKII-HDIIEscherichia coli K-12
Aspartate-semialdehyde dehydrogenaseASA dehydrogenase; ASADH; EC 1.2.1.11; Aspartate-beta-semialdehyde dehydrogenaseEscherichia coli K-12

Compounds (11)

CompoundDescription
hydronium ion
pyruvic acidAn intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
Orthophosphate
Adenosine TriphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
threonineAn essential amino acid occurring naturally in the L-form, which is the active form. It is found in eggs, milk, gelatin, and other proteins.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
homoserine
o-phosphohomoserineRN given refers to L-isomer
aspartic semialdehydeRN given refers to cpd without isomeric designation
creolinfrom refined coal tar oils