Page last updated: 2024-10-06

Secondary Metabolites: Methylerythritol Phosphate and Polyisoprenoid Biosynthesis

Proteins (11)

ProteinSynonymsTaxonomy
Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)EC 2.5.1.31; Ditrans,polycis-undecaprenylcistransferase; Undecaprenyl diphosphate synthase; UDS; Undecaprenyl pyrophosphate synthase; UPP synthaseEscherichia coli K-12
4-hydroxy-3-methylbut-2-enyl diphosphate reductaseHMBPP reductase; EC 1.17.7.4; 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductaseEscherichia coli K-12
Farnesyl diphosphate synthaseFPP synthase; EC 2.5.1.10; (2E,6E)-farnesyl diphosphate synthase; GeranyltranstransferaseEscherichia coli K-12
1-deoxy-D-xylulose 5-phosphate reductoisomeraseDXP reductoisomerase; EC 1.1.1.267; 1-deoxyxylulose-5-phosphate reductoisomerase; 2-C-methyl-D-erythritol 4-phosphate synthaseEscherichia coli K-12
Octaprenyl diphosphate synthaseEC 2.5.1.90; All-trans-octaprenyl-diphosphate synthase; Octaprenyl pyrophosphate synthase; OPP synthaseEscherichia coli K-12
4-diphosphocytidyl-2-C-methyl-D-erythritol kinaseCMK; EC 2.7.1.148; 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinaseEscherichia coli K-12
1-deoxy-D-xylulose-5-phosphate synthaseEC 2.2.1.7; 1-deoxyxylulose-5-phosphate synthase; DXP synthase; DXPSEscherichia coli K-12
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthaseMECDP-synthase; MECPP-synthase; MECPS; EC 4.6.1.12Escherichia coli K-12
Isopentenyl-diphosphate Delta-isomeraseIPP isomerase; EC 5.3.3.2; IPP:DMAPP isomerase; Isopentenyl pyrophosphate isomeraseEscherichia coli K-12
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin)EC 1.17.7.3; 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Protein GcpE; Protein EEscherichia coli K-12
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferaseEC 2.7.7.60; 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; CDP-ME synthase; MEP cytidylyltransferase; MCTEscherichia coli K-12

Compounds (18)

CompoundDescription
hydronium ion
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
Adenosine TriphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
isopentenyl pyrophosphatesubstrate for isopentenyl pyrophosphate isomerase; RN given refers to unlabeled cpd; a nonpeptide mycobacterial antigen that stimulates gamma delta T cells
farnesyl pyrophosphatea sesquiterpene that dimerizes to SQUALENE; RN given refers to cpd without isomeric designation
geranyl pyrophosphateRN given refers to (E)-isomer
cytidine monophosphateCytidine (dihydrogen phosphate). A cytosine nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' position.
cytidine triphosphateCytidine 5'-(tetrahydrogen triphosphate). A cytosine nucleotide containing three phosphate groups esterified to the sugar moiety.
Glyceraldehyde 3-PhosphateAn aldotriose which is an important intermediate in glycolysis and in tryptophan biosynthesis.
4-hydroxy-3-methylbut-2-enyl pyrophosphatestructure in first source
2-C-methyl-D-erythritol 2,4-cyclodiphosphate
4-diphosphocytidyl-2-c-methylerythritolstructure in first source
1-deoxy-d-xylulose 5-phosphate
creolinfrom refined coal tar oils
pyrophosphate
3,3-dimethylallyl pyrophosphateisomeric with isopentenyl pyrophosphate