Page last updated: 2024-10-06

Secondary Metabolites: Cysteine Biosynthesis from Serine

Proteins (7)

ProteinSynonymsTaxonomy
D-3-phosphoglycerate dehydrogenasePGDH; EC 1.1.1.95; 2-oxoglutarate reductase; 1.1.1.399Escherichia coli K-12
Phosphoserine phosphatasePSP; PSPase; EC 3.1.3.3; O-phosphoserine phosphohydrolaseEscherichia coli K-12
Phosphoserine aminotransferaseEC 2.6.1.52; Phosphohydroxythreonine aminotransferase; PSATEscherichia coli K-12
Cysteine synthase ACSase A; EC 2.5.1.47; O-acetylserine (thiol)-lyase A; OAS-TL A; O-acetylserine sulfhydrylase A; S-carboxymethylcysteine synthase; 4.5.1.5; Sulfate starvation-induced protein 5; SSI5Escherichia coli K-12
Serine acetyltransferaseSAT; EC 2.3.1.30Escherichia coli K-12
Cysteine synthase BCSase B; EC 2.5.1.47; O-acetylserine (thiol)-lyase B; OAS-TL B; O-acetylserine sulfhydrylase BEscherichia coli K-12
NADP-dependent 3-hydroxy acid dehydrogenase YdfGL-allo-threonine dehydrogenase; 1.1.1.381; Malonic semialdehyde reductase; 1.1.1.298Escherichia coli K-12

Compounds (17)

CompoundDescription
hydronium ion
Orthophosphate
acetic acidProduct of the oxidation of ethanol and of the destructive distillation of wood. It is used locally, occasionally internally, as a counterirritant and also as a reagent. (Stedman, 26th ed)
glutamic acidA non-essential amino acid naturally occurring in the L-form. Glutamic acid is the most common excitatory neurotransmitter in the CENTRAL NERVOUS SYSTEM.
NADH
cysteineA thiol-containing non-essential amino acid that is oxidized to form CYSTINE.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Coenzyme A
phosphohydroxypyruvic acid
phosphoserineThe phosphoric acid ester of serine.
alpha-ketoglutaric acid
NADA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
serineA non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
3-phosphoglycerate
acetyl coenzyme aAcetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.
creolinfrom refined coal tar oils
Slc7a2 protein, mouseRefSeq NM_007514