Page last updated: 2024-10-06
SLC transporter disorders
Proteins (42)
| Protein | Synonyms | Taxonomy |
|---|---|---|
| Basigin | 5F7; Collagenase stimulatory factor; Extracellular matrix metalloproteinase inducer; EMMPRIN; Hepatoma-associated antigen; HAb18G; Leukocyte activation antigen M6; OK blood group antigen; Tumor cell-derived collagenase stimulatory factor; TCSF | Homo sapiens (human) |
| Sodium-dependent noradrenaline transporter | Norepinephrine transporter; NET; Solute carrier family 6 member 2 | Homo sapiens (human) |
| Vasopressin V2 receptor | V2R; AVPR V2; Antidiuretic hormone receptor; Renal-type arginine vasopressin receptor | Homo sapiens (human) |
| Hexokinase-4 | HK4; EC 2.7.1.1; Glucokinase; Hexokinase type IV; HK IV; Hexokinase-D | Homo sapiens (human) |
| Glucokinase regulatory protein | GKRP; Glucokinase regulator | Homo sapiens (human) |
| High affinity choline transporter 1 | Hemicholinium-3-sensitive choline transporter; CHT; Solute carrier family 5 member 7 | Homo sapiens (human) |
| Solute carrier organic anion transporter family member 1B3 | Liver-specific organic anion transporter 2; LST-2; Organic anion transporter 8; Organic anion-transporting polypeptide 8; OATP-8; Solute carrier family 21 member 8 | Homo sapiens (human) |
| E3 SUMO-protein ligase RanBP2 | EC 2.3.2.-; 358 kDa nucleoporin; Nuclear pore complex protein Nup358; Nucleoporin Nup358; Ran-binding protein 2; RanBP2; p270 | Homo sapiens (human) |
| Solute carrier family 40 member 1 | Ferroportin-1; Iron-regulated transporter 1 | Homo sapiens (human) |
| Nuclear pore complex protein Nup155 | 155 kDa nucleoporin; Nucleoporin Nup155 | Homo sapiens (human) |
| Ceruloplasmin | EC 1.16.3.1; Ferroxidase | Homo sapiens (human) |
| Nuclear pore complex protein Nup88 | 88 kDa nucleoporin; Nucleoporin Nup88 | Homo sapiens (human) |
| mRNA export factor | Rae1 protein homolog; mRNA-associated protein mrnp 41 | Homo sapiens (human) |
| Nuclear pore membrane glycoprotein 210 | Nuclear pore protein gp210; Nuclear envelope pore membrane protein POM 210; POM210; Nucleoporin Nup210; Pore membrane protein of 210 kDa | Homo sapiens (human) |
| Nucleoporin NUP42 | NLP-1; NUP42 homolog; Nucleoporin hCG1; Nucleoporin-42; Nucleoporin-like protein 2 | Homo sapiens (human) |
| Sodium/potassium/calcium exchanger 1 | Na(+)/K(+)/Ca(2+)-exchange protein 1; Retinal rod Na-Ca+K exchanger; Solute carrier family 24 member 1 | Homo sapiens (human) |
| 4F2 cell-surface antigen heavy chain | 4F2hc; 4F2 heavy chain antigen; Lymphocyte activation antigen 4F2 large subunit; Solute carrier family 3 member 2 | Homo sapiens (human) |
| Nuclear pore complex protein Nup214 | 214 kDa nucleoporin; Nucleoporin Nup214; Protein CAN | Homo sapiens (human) |
| Nuclear pore glycoprotein p62 | 62 kDa nucleoporin; Nucleoporin Nup62 | Homo sapiens (human) |
| Nuclear pore complex protein Nup153 | 153 kDa nucleoporin; Nucleoporin Nup153 | Homo sapiens (human) |
| Protein SEC13 homolog | GATOR complex protein SEC13; SEC13-like protein 1; SEC13-related protein | Homo sapiens (human) |
| Nuclear pore complex protein Nup107 | 107 kDa nucleoporin; Nucleoporin Nup107 | Homo sapiens (human) |
| CMP-sialic acid transporter | CMP-SA-Tr; CMP-Sia-Tr; Solute carrier family 35 member A1 | Homo sapiens (human) |
| b(0,+)-type amino acid transporter 1 | b(0,+)AT1; Glycoprotein-associated amino acid transporter b0,+AT1; Solute carrier family 7 member 9 | Homo sapiens (human) |
| Neutral and basic amino acid transport protein rBAT | NBAT; D2h; Solute carrier family 3 member 1; b(0,+)-type amino acid transport protein | Homo sapiens (human) |
| Nuclear pore complex protein Nup160 | 160 kDa nucleoporin; Nucleoporin Nup160 | Homo sapiens (human) |
| Nucleoporin NUP188 | hNup188 | Homo sapiens (human) |
| Nucleoporin p54 | 54 kDa nucleoporin | Homo sapiens (human) |
| Sodium/hydrogen exchanger 9 | Na(+)/H(+) exchanger 9; NHE-9; Solute carrier family 9 member 9 | Homo sapiens (human) |
| Nuclear pore complex protein Nup93 | 93 kDa nucleoporin; Nucleoporin Nup93 | Homo sapiens (human) |
| Vesicular glutamate transporter 3 | VGluT3; Solute carrier family 17 member 8 | Homo sapiens (human) |
| Nucleoporin Nup43 | Nup107-160 subcomplex subunit Nup43; p42 | Homo sapiens (human) |
| Nucleoporin Nup37 | p37; Nup107-160 subcomplex subunit Nup37 | Homo sapiens (human) |
| Nucleoporin NUP35 | 35 kDa nucleoporin; Mitotic phosphoprotein 44; MP-44; Nuclear pore complex protein Nup53; Nucleoporin NUP53 | Homo sapiens (human) |
| Nuclear pore complex protein Nup133 | 133 kDa nucleoporin; Nucleoporin Nup133 | Homo sapiens (human) |
| Nuclear pore complex protein Nup205 | 205 kDa nucleoporin; Nucleoporin Nup205 | Homo sapiens (human) |
| Hephaestin | EC 1.-.-.- | Homo sapiens (human) |
| Nucleoporin NDC1 | hNDC1; Transmembrane protein 48 | Homo sapiens (human) |
| Nuclear pore complex protein Nup85 | 85 kDa nucleoporin; FROUNT; Nucleoporin Nup75; Nucleoporin Nup85; Pericentrin-1 | Homo sapiens (human) |
| Sodium- and chloride-dependent transporter XTRP3 | Sodium/imino-acid transporter 1; Solute carrier family 6 member 20; Transporter rB21A homolog | Homo sapiens (human) |
| Aladin | Adracalin | Homo sapiens (human) |
| Nuclear pore complex protein Nup50 | 50 kDa nucleoporin; Nuclear pore-associated protein 60 kDa-like; Nucleoporin Nup50 | Homo sapiens (human) |
Compounds (29)
| Compound | Description |
|---|---|
| hydronium ion | |
| l-lactic acid | |
| Arginine | An essential amino acid that is physiologically active in the L-form. |
| Ammonium | |
| Copper | A heavy metal trace element with the atomic symbol Cu, atomic number 29, and atomic weight 63.55. |
| Copper | A heavy metal trace element with the atomic symbol Cu, atomic number 29, and atomic weight 63.55. |
| Calcium | A basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes. |
| iron | A metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN. |
| Iron | A metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN. |
| iodine | A nonmetallic element of the halogen group that is represented by the atomic symbol I, atomic number 53, and atomic weight of 126.90. It is a nutritionally essential element, especially important in thyroid hormone synthesis. In solution, it has anti-infective properties and is used topically. |
| choline | A basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism. |
| chlorine | An element with atomic symbol Cl, atomic number 17, and atomic weight 35, and member of the halogen family. |
| Zinc | A metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn. |
| Orthophosphate | |
| Dopamine Hydrochloride | |
| hydrogen carbonate | |
| potassium | An element in the alkali group of metals with an atomic symbol K, atomic number 19, and atomic weight 39.10. It is the chief cation in the intracellular fluid of muscle and other cells. Potassium ion is a strong electrolyte that plays a significant role in the regulation of fluid volume and maintenance of the WATER-ELECTROLYTE BALANCE. |
| Sodium | A member of the alkali group of metals. It has the atomic symbol Na, atomic number 11, and atomic weight 23. |
| Oxygen | An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration. |
| cytarabine | A pyrimidine nucleoside analog that is used mainly in the treatment of leukemia, especially acute non-lymphoblastic leukemia. Cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. Its actions are specific for the S phase of the cell cycle. It also has antiviral and immunosuppressant properties. (From Martindale, The Extra Pharmacopoeia, 30th ed, p472) |
| uric acid | An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN. |
| carnitine | A constituent of STRIATED MUSCLE and LIVER. It is an amino acid derivative and an essential cofactor for fatty acid metabolism. |
| glutamate | |
| adenosine triphosphate | An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter. |
| Cytidine Monophosphate | Cytidine (dihydrogen phosphate). A cytosine nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' position. |
| Bilirubin | A bile pigment that is a degradation product of HEME. |
| Uridine Monophosphate | 5'-Uridylic acid. A uracil nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' position. |
| Acetyl Coenzyme A | Acetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent. |
| glucose | A primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient replacement. |