Page last updated: 2024-10-06

SLC transporter disorders

Proteins (42)

ProteinSynonymsTaxonomy
Basigin5F7; Collagenase stimulatory factor; Extracellular matrix metalloproteinase inducer; EMMPRIN; Hepatoma-associated antigen; HAb18G; Leukocyte activation antigen M6; OK blood group antigen; Tumor cell-derived collagenase stimulatory factor; TCSFHomo sapiens (human)
Sodium-dependent noradrenaline transporter Norepinephrine transporter; NET; Solute carrier family 6 member 2Homo sapiens (human)
Vasopressin V2 receptorV2R; AVPR V2; Antidiuretic hormone receptor; Renal-type arginine vasopressin receptorHomo sapiens (human)
Hexokinase-4HK4; EC 2.7.1.1; Glucokinase; Hexokinase type IV; HK IV; Hexokinase-DHomo sapiens (human)
Glucokinase regulatory proteinGKRP; Glucokinase regulatorHomo sapiens (human)
High affinity choline transporter 1Hemicholinium-3-sensitive choline transporter; CHT; Solute carrier family 5 member 7Homo sapiens (human)
Solute carrier organic anion transporter family member 1B3Liver-specific organic anion transporter 2; LST-2; Organic anion transporter 8; Organic anion-transporting polypeptide 8; OATP-8; Solute carrier family 21 member 8Homo sapiens (human)
E3 SUMO-protein ligase RanBP2EC 2.3.2.-; 358 kDa nucleoporin; Nuclear pore complex protein Nup358; Nucleoporin Nup358; Ran-binding protein 2; RanBP2; p270Homo sapiens (human)
Solute carrier family 40 member 1Ferroportin-1; Iron-regulated transporter 1Homo sapiens (human)
Nuclear pore complex protein Nup155155 kDa nucleoporin; Nucleoporin Nup155Homo sapiens (human)
CeruloplasminEC 1.16.3.1; FerroxidaseHomo sapiens (human)
Nuclear pore complex protein Nup8888 kDa nucleoporin; Nucleoporin Nup88Homo sapiens (human)
mRNA export factorRae1 protein homolog; mRNA-associated protein mrnp 41Homo sapiens (human)
Nuclear pore membrane glycoprotein 210Nuclear pore protein gp210; Nuclear envelope pore membrane protein POM 210; POM210; Nucleoporin Nup210; Pore membrane protein of 210 kDaHomo sapiens (human)
Nucleoporin NUP42NLP-1; NUP42 homolog; Nucleoporin hCG1; Nucleoporin-42; Nucleoporin-like protein 2Homo sapiens (human)
Sodium/potassium/calcium exchanger 1Na(+)/K(+)/Ca(2+)-exchange protein 1; Retinal rod Na-Ca+K exchanger; Solute carrier family 24 member 1Homo sapiens (human)
4F2 cell-surface antigen heavy chain4F2hc; 4F2 heavy chain antigen; Lymphocyte activation antigen 4F2 large subunit; Solute carrier family 3 member 2Homo sapiens (human)
Nuclear pore complex protein Nup214214 kDa nucleoporin; Nucleoporin Nup214; Protein CANHomo sapiens (human)
Nuclear pore glycoprotein p6262 kDa nucleoporin; Nucleoporin Nup62Homo sapiens (human)
Nuclear pore complex protein Nup153153 kDa nucleoporin; Nucleoporin Nup153Homo sapiens (human)
Protein SEC13 homologGATOR complex protein SEC13; SEC13-like protein 1; SEC13-related proteinHomo sapiens (human)
Nuclear pore complex protein Nup107107 kDa nucleoporin; Nucleoporin Nup107Homo sapiens (human)
CMP-sialic acid transporterCMP-SA-Tr; CMP-Sia-Tr; Solute carrier family 35 member A1Homo sapiens (human)
b(0,+)-type amino acid transporter 1b(0,+)AT1; Glycoprotein-associated amino acid transporter b0,+AT1; Solute carrier family 7 member 9Homo sapiens (human)
Neutral and basic amino acid transport protein rBATNBAT; D2h; Solute carrier family 3 member 1; b(0,+)-type amino acid transport proteinHomo sapiens (human)
Nuclear pore complex protein Nup160160 kDa nucleoporin; Nucleoporin Nup160Homo sapiens (human)
Nucleoporin NUP188hNup188Homo sapiens (human)
Nucleoporin p5454 kDa nucleoporinHomo sapiens (human)
Sodium/hydrogen exchanger 9Na(+)/H(+) exchanger 9; NHE-9; Solute carrier family 9 member 9Homo sapiens (human)
Nuclear pore complex protein Nup9393 kDa nucleoporin; Nucleoporin Nup93Homo sapiens (human)
Vesicular glutamate transporter 3VGluT3; Solute carrier family 17 member 8Homo sapiens (human)
Nucleoporin Nup43Nup107-160 subcomplex subunit Nup43; p42Homo sapiens (human)
Nucleoporin Nup37p37; Nup107-160 subcomplex subunit Nup37Homo sapiens (human)
Nucleoporin NUP3535 kDa nucleoporin; Mitotic phosphoprotein 44; MP-44; Nuclear pore complex protein Nup53; Nucleoporin NUP53Homo sapiens (human)
Nuclear pore complex protein Nup133133 kDa nucleoporin; Nucleoporin Nup133Homo sapiens (human)
Nuclear pore complex protein Nup205205 kDa nucleoporin; Nucleoporin Nup205Homo sapiens (human)
HephaestinEC 1.-.-.-Homo sapiens (human)
Nucleoporin NDC1hNDC1; Transmembrane protein 48Homo sapiens (human)
Nuclear pore complex protein Nup8585 kDa nucleoporin; FROUNT; Nucleoporin Nup75; Nucleoporin Nup85; Pericentrin-1Homo sapiens (human)
Sodium- and chloride-dependent transporter XTRP3Sodium/imino-acid transporter 1; Solute carrier family 6 member 20; Transporter rB21A homologHomo sapiens (human)
AladinAdracalinHomo sapiens (human)
Nuclear pore complex protein Nup5050 kDa nucleoporin; Nuclear pore-associated protein 60 kDa-like; Nucleoporin Nup50Homo sapiens (human)

Compounds (29)

CompoundDescription
hydronium ion
l-lactic acid
ArginineAn essential amino acid that is physiologically active in the L-form.
Ammonium
CopperA heavy metal trace element with the atomic symbol Cu, atomic number 29, and atomic weight 63.55.
CopperA heavy metal trace element with the atomic symbol Cu, atomic number 29, and atomic weight 63.55.
CalciumA basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
ironA metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN.
IronA metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN.
iodineA nonmetallic element of the halogen group that is represented by the atomic symbol I, atomic number 53, and atomic weight of 126.90. It is a nutritionally essential element, especially important in thyroid hormone synthesis. In solution, it has anti-infective properties and is used topically.
cholineA basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism.
chlorineAn element with atomic symbol Cl, atomic number 17, and atomic weight 35, and member of the halogen family.
ZincA metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn.
Orthophosphate
Dopamine Hydrochloride
hydrogen carbonate
potassiumAn element in the alkali group of metals with an atomic symbol K, atomic number 19, and atomic weight 39.10. It is the chief cation in the intracellular fluid of muscle and other cells. Potassium ion is a strong electrolyte that plays a significant role in the regulation of fluid volume and maintenance of the WATER-ELECTROLYTE BALANCE.
SodiumA member of the alkali group of metals. It has the atomic symbol Na, atomic number 11, and atomic weight 23.
OxygenAn element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
cytarabineA pyrimidine nucleoside analog that is used mainly in the treatment of leukemia, especially acute non-lymphoblastic leukemia. Cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. Its actions are specific for the S phase of the cell cycle. It also has antiviral and immunosuppressant properties. (From Martindale, The Extra Pharmacopoeia, 30th ed, p472)
uric acidAn oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
carnitineA constituent of STRIATED MUSCLE and LIVER. It is an amino acid derivative and an essential cofactor for fatty acid metabolism.
glutamate
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
Cytidine MonophosphateCytidine (dihydrogen phosphate). A cytosine nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' position.
BilirubinA bile pigment that is a degradation product of HEME.
Uridine Monophosphate5'-Uridylic acid. A uracil nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' position.
Acetyl Coenzyme AAcetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.
glucoseA primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient replacement.