Page last updated: 2024-10-06

SHP2 signaling

Proteins (55)

ProteinSynonymsTaxonomy
Platelet-derived growth factor subunit BPDGF subunit B; PDGF-2; Platelet-derived growth factor B chain; Platelet-derived growth factor beta polypeptide; Proto-oncogene c-SisHomo sapiens (human)
Insulin receptor substrate 1IRS-1Homo sapiens (human)
Tyrosine-protein kinase JAK2EC 2.7.10.2; Janus kinase 2; JAK-2Homo sapiens (human)
Epidermal growth factor receptorEC 2.7.10.1; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1Homo sapiens (human)
RAF proto-oncogene serine/threonine-protein kinaseEC 2.7.11.1; Proto-oncogene c-RAF; cRaf; Raf-1Homo sapiens (human)
High affinity nerve growth factor receptorEC 2.7.10.1; Neurotrophic tyrosine kinase receptor type 1; TRK1-transforming tyrosine kinase protein; Tropomyosin-related kinase A; Tyrosine kinase receptor; Tyrosine kinase receptor A; Trk-A; gp140trk; p140-TrkAHomo sapiens (human)
Tyrosine-protein kinase LckEC 2.7.10.2; Leukocyte C-terminal Src kinase; LSK; Lymphocyte cell-specific protein-tyrosine kinase; Protein YT16; Proto-oncogene Lck; T cell-specific protein-tyrosine kinase; p56-LCKHomo sapiens (human)
Insulin-like growth factor 1 receptorEC 2.7.10.1; Insulin-like growth factor I receptor; IGF-I receptorHomo sapiens (human)
Platelet-derived growth factor receptor betaPDGF-R-beta; PDGFR-beta; EC 2.7.10.1; Beta platelet-derived growth factor receptor; Beta-type platelet-derived growth factor receptor; CD140 antigen-like family member B; Platelet-derived growth factor receptor 1; PDGFR-1Homo sapiens (human)
Fibroblast growth factor receptor 3FGFR-3; EC 2.7.10.1Homo sapiens (human)
Vascular endothelial growth factor receptor 2VEGFR-2; EC 2.7.10.1; Fetal liver kinase 1; FLK-1; Kinase insert domain receptor; KDR; Protein-tyrosine kinase receptor flk-1Homo sapiens (human)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformPI3-kinase subunit alpha; PI3K-alpha; PI3Kalpha; PtdIns-3-kinase subunit alpha; EC 2.7.1.137; EC 2.7.1.153; Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha; PtdIns-3-kinase subunit p110-alpha; p110alpha; Phosphoinositide 3-kHomo sapiens (human)
Tyrosine-protein kinase JAK3EC 2.7.10.2; Janus kinase 3; JAK-3; Leukocyte janus kinase; L-JAKHomo sapiens (human)
Dual specificity mitogen-activated protein kinase kinase 1MAP kinase kinase 1; MAPKK 1; MKK1; EC 2.7.12.2; ERK activator kinase 1; MAPK/ERK kinase 1; MEK 1Homo sapiens (human)
Angiopoietin-1 receptorEC 2.7.10.1; Endothelial tyrosine kinase; Tunica interna endothelial cell kinase; Tyrosine kinase with Ig and EGF homology domains-2; Tyrosine-protein kinase receptor TEK; Tyrosine-protein kinase receptor TIE-2; hTIE2; p140 TEKHomo sapiens (human)
Tyrosine-protein phosphatase non-receptor type 11EC 3.1.3.48; Protein-tyrosine phosphatase 1D; PTP-1D; Protein-tyrosine phosphatase 2C; PTP-2C; SH-PTP2; SHP-2; Shp2; SH-PTP3Homo sapiens (human)
NT-3 growth factor receptorEC 2.7.10.1; GP145-TrkC; Trk-C; Neurotrophic tyrosine kinase receptor type 3; TrkC tyrosine kinaseHomo sapiens (human)
Interferon gamma receptor 1IFN-gamma receptor 1; IFN-gamma-R1; CDw119; Interferon gamma receptor alpha-chain; IFN-gamma-R-alphaHomo sapiens (human)
Rho GTPase-activating protein 35Glucocorticoid receptor DNA-binding factor 1; Glucocorticoid receptor repression factor 1; GRF-1; Rho GAP p190A; p190-AHomo sapiens (human)
cAMP-dependent protein kinase catalytic subunit alphaPKA C-alpha; EC 2.7.11.11Homo sapiens (human)
Fibroblast growth factor receptor 2FGFR-2; EC 2.7.10.1; K-sam; KGFR; Keratinocyte growth factor receptorHomo sapiens (human)
Tyrosine-protein kinase JAK1EC 2.7.10.2; Janus kinase 1; JAK-1Homo sapiens (human)
Phosphatidylinositol 3-kinase regulatory subunit alphaPI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; PI3-kinase subunit p85-alpha; PtdIns-3-kinase regulatory subunit p85-alphaHomo sapiens (human)
SHC-transforming protein 1SHC-transforming protein 3; SHC-transforming protein A; Src homology 2 domain-containing-transforming protein C1; SH2 domain protein C1Homo sapiens (human)
Growth factor receptor-bound protein 2Adapter protein GRB2; Protein Ash; SH2/SH3 adapter GRB2Homo sapiens (human)
BDNF/NT-3 growth factors receptorEC 2.7.10.1; GP145-TrkB; Trk-B; Neurotrophic tyrosine kinase receptor type 2; TrkB tyrosine kinase; Tropomyosin-related kinase BHomo sapiens (human)
Vascular endothelial growth factor AVEGF-A; Vascular permeability factor; VPFHomo sapiens (human)
Guanine nucleotide-binding protein G(i) subunit alpha-1Adenylate cyclase-inhibiting G alpha proteinHomo sapiens (human)
Beta-nerve growth factorBeta-NGFHomo sapiens (human)
Son of sevenless homolog 1SOS-1Homo sapiens (human)
Brain-derived neurotrophic factorBDNF; AbrineurinHomo sapiens (human)
Syndecan-2SYND2; Fibroglycan; Heparan sulfate proteoglycan core protein; HSPGHomo sapiens (human)
GRB2-associated-binding protein 1GRB2-associated binder 1; Growth factor receptor bound protein 2-associated protein 1Homo sapiens (human)
Pro-epidermal growth factorEGFHomo sapiens (human)
Interleukin-6IL-6; B-cell stimulatory factor 2; BSF-2; CTL differentiation factor; CDF; Hybridoma growth factor; Interferon beta-2; IFN-beta-2Homo sapiens (human)
Nitric oxide synthase, endothelialEC 1.14.13.39; Constitutive NOS; cNOS; EC-NOS; Endothelial NOS; eNOS; NOS type III; NOSIIIHomo sapiens (human)
Signal transducer and activator of transcription 1-alpha/betaTranscription factor ISGF-3 components p91/p84Homo sapiens (human)
Transforming protein RhoAEC 3.6.5.2; Rho cDNA clone 12; h12Homo sapiens (human)
Interferon gammaIFN-gamma; Immune interferonHomo sapiens (human)
Interleukin-2 receptor subunit alphaIL-2 receptor subunit alpha; IL-2-RA; IL-2R subunit alpha; IL2-RA; TAC antigen; p55Homo sapiens (human)
Guanine nucleotide-binding protein G(i) subunit alpha-3G(i) alpha-3Homo sapiens (human)
Neurotrophin-4NT-4; Neurotrophin-5; NT-5; Neutrophic factor 4Homo sapiens (human)
Interleukin-6 receptor subunit alphaIL-6 receptor subunit alpha; IL-6R subunit alpha; IL-6R-alpha; IL-6RA; IL-6R 1; Membrane glycoprotein 80; gp80Homo sapiens (human)
Interleukin-6 receptor subunit betaIL-6 receptor subunit beta; IL-6R subunit beta; IL-6R-beta; IL-6RB; CDw130; Interleukin-6 signal transducer; Membrane glycoprotein 130; gp130; Oncostatin-M receptor subunit alphaHomo sapiens (human)
Interleukin-2IL-2; T-cell growth factor; TCGFHomo sapiens (human)
Angiopoietin-1ANG-1Homo sapiens (human)
Interleukin-2 receptor subunit betaIL-2 receptor subunit beta; IL-2R subunit beta; IL-2RB; High affinity IL-2 receptor subunit beta; Interleukin-15 receptor subunit beta; p70-75; p75Homo sapiens (human)
AfadinALL1-fused gene from chromosome 6 protein; Protein AF-6; Afadin adherens junction formation factorHomo sapiens (human)
Neurotrophin-3NT-3; HDNF; Nerve growth factor 2; NGF-2; Neurotrophic factorHomo sapiens (human)
Cytokine receptor common subunit gammaInterleukin-2 receptor subunit gamma; IL-2 receptor subunit gamma; IL-2R subunit gamma; IL-2RG; gammaC; p64Homo sapiens (human)
GRB2-associated-binding protein 2GRB2-associated binder 2; Growth factor receptor bound protein 2-associated protein 2; pp100Homo sapiens (human)
Phosphoprotein associated with glycosphingolipid-enriched microdomains 1Csk-binding protein; Transmembrane adapter protein PAG; Transmembrane phosphoprotein CbpHomo sapiens (human)
LIM domain transcription factor LMO4Breast tumor autoantigen; LIM domain only protein 4; LMO-4Homo sapiens (human)
Fibroblast growth factor receptor substrate 2FGFR substrate 2; FGFR-signaling adaptor SNT; Suc1-associated neurotrophic factor target 1; SNT-1Homo sapiens (human)
RecName: Full=Insulin-like growth factor IA; Short=IGF-IA; AltName: Full=Somatomedin-C; AltName: Full=Mechano growth factor; Short=MGF; Flags: PrecursorHomo sapiens (human)

Compounds (0)

CompoundDescription